Search Results - "Michael D. Hoos"
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1
Reduced Levels of Cerebrospinal Fluid/Plasma Aβ40 as an Early Biomarker for Cerebral Amyloid Angiopathy in RTg-DI Rats
Published in International journal of molecular sciences (01-01-2020)“…The accumulation of fibrillar amyloid β-protein (Aβ) in blood vessels of the brain, the condition known as cerebral amyloid angiopathy (CAA), is a common small…”
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2
A Novel Transgenic Rat Model of Robust Cerebral Microvascular Amyloid with Prominent Vasculopathy
Published in The American journal of pathology (01-12-2018)“…Accumulation of fibrillar amyloid β protein in blood vessels of the brain, a condition known as cerebral amyloid angiopathy (CAA), is a common pathology of…”
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3
Longitudinal Study of Differential Protein Expression in an Alzheimer’s Mouse Model Lacking Inducible Nitric Oxide Synthase
Published in Journal of proteome research (04-10-2013)“…Alzheimer’s disease (AD) is a complex neurodegenerative process that involves altered brain immune, neuronal and metabolic functions. Understanding the…”
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4
Fine Mapping of the Amyloid β‑Protein Binding Site on Myelin Basic Protein
Published in Biochemistry (Easton) (16-04-2013)“…The assembly and deposition of amyloid β-protein (Aβ) in brain is a key pathological feature of Alzheimer’s disease and related disorders. Factors have been…”
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5
The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment
Published in Molecular neurodegeneration (17-11-2014)“…Mouse models are used in the study of human disease. Despite well-known homologies, the difference in immune response between mice and humans impacts the…”
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N-terminal Domain of Myelin Basic Protein Inhibits Amyloid β-Protein Fibril Assembly
Published in The Journal of biological chemistry (12-11-2010)“…Accumulation of amyloid β-protein (Aβ) into brain parenchymal plaques and the cerebral vasculature is a pathological feature of Alzheimer disease and related…”
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7
Myelin Basic Protein Binds to and Inhibits the Fibrillar Assembly of Aβ42 in Vitro
Published in Biochemistry (Easton) (09-06-2009)“…The deposition of amyloid β-protein (Aβ) fibrils into plaques within the brain parenchyma and along cerebral blood vessels is a hallmark of Alzheimer’s…”
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Inhibition of Familial Cerebral Amyloid Angiopathy Mutant Amyloid β-Protein Fibril Assembly by Myelin Basic Protein
Published in The Journal of biological chemistry (30-03-2007)“…Deposition of fibrillar amyloid β-protein (Aβ) in the brain is a prominent pathological feature of Alzheimer disease and related disorders, including familial…”
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9
N-terminal Domain of Myelin Basic Protein Inhibits Amyloid b-Protein Fibril Assembly
Published in The Journal of biological chemistry (01-11-2010)“…Accumulation of amyloid b-protein (Ab) into brain parenchymal plaques and the cerebral vasculature is a pathological feature of Alzheimer disease and related…”
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Journal Article -
10
Myelin Basic Protein Binds to and Inhibits the Fibrillar Assembly of Ab42 in Vitro
Published in Biochemistry (Easton) (22-04-2009)“…The deposition of amyloid *b-protein (A*b) fibrils into plaques within the brain parenchyma and along cerebral blood vessels is a hallmark of Alzheimer's…”
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11
Inhibition of Familial Cerebral Amyloid Angiopathy Mutant Amyloid β-Protein Fibril Assembly by Myelin Basic Protein
Published in The Journal of biological chemistry (30-03-2007)“…Deposition of fibrillar amyloid β-protein (Aβ) in the brain is a prominent pathological feature of Alzheimer disease and related disorders, including…”
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Journal Article -
12
Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro
Published in Biochemistry (Easton) (09-06-2009)“…The deposition of amyloid beta-protein (Abeta) fibrils into plaques within the brain parenchyma and along cerebral blood vessels is a hallmark of Alzheimer's…”
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