Search Results - "Michael, N."

Decision Making and Sequential Sampling from Memory by Shadlen, Michael N., Shohamy, Daphna

“…Decisions take time, and as a rule more difficult decisions take more time. But this only raises the question of what consumes the time. For decisions informed…”
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Choice Certainty Is Informed by Both Evidence and Decision Time by Kiani, Roozbeh, Corthell, Leah, Shadlen, Michael N.

“…“Degree of certainty” refers to the subjective belief, prior to feedback, that a decision is correct. A reliable estimate of certainty is essential for…”
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mTOR signalling and cellular metabolism are mutual determinants in cancer by Mossmann, Dirk, Park, Sujin, Hall, Michael N.

“…Oncogenic signalling and metabolic alterations are interrelated in cancer cells. mTOR, which is frequently activated in cancer, controls cell growth and…”
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Nutrient sensing and TOR signaling in yeast and mammals by González, Asier, Hall, Michael N

“…Coordinating cell growth with nutrient availability is critical for cell survival. The evolutionarily conserved TOR (target of rapamycin) controls cell growth…”
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A Neural Mechanism for Sensing and Reproducing a Time Interval by Jazayeri, Mehrdad, Shadlen, Michael N.

“…Timing plays a crucial role in sensorimotor function. However, the neural mechanisms that enable the brain to flexibly measure and reproduce time intervals are…”
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Role of the small intestine, colon and microbiota in determining the metabolic fate of polyphenols by Williamson, Gary, Clifford, Michael N.

“…[Display omitted] (Poly)phenols are a large group of compounds, found in food, beverages, dietary supplements and herbal medicines. Owing to interest in their…”
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Investigating metformin for cancer prevention and treatment: the end of the beginning by Pollak, Michael N

“…Laboratory research and pharmacoepidemiology are providing converging evidence that the widely used antidiabetic drug metformin has antineoplastic activity,…”
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Making new contacts: the mTOR network in metabolism and signalling crosstalk by Shimobayashi, Mitsugu, Hall, Michael N.

“…Our understanding of the downstream effectors and upstream regulators of target of rapamycin (TOR) signalling continues to grow. In particular, recent global…”
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Molecular Pathways: Adiponectin and Leptin Signaling in Cancer by VANSAUN, Michael N

“…The increasing percentage of obese individuals in the population and its independent association of increased risk for the development of cancer have…”
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Insight into the confusion over surfactant co-formulants in glyphosate-based herbicides by Mesnage, Robin, Benbrook, Charles, Antoniou, Michael N.

“…Glyphosate is the active ingredient in glyphosate-based herbicides (GBHs). Other chemicals in GBHs are presumed as inert by regulatory authorities and are…”
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Decision Making as a Window on Cognition by Shadlen, Michael N., Kiani, Roozbeh

“…A decision is a commitment to a proposition or plan of action based on information and values associated with the possible outcomes. The process operates in a…”
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Integrating Data On Social Determinants Of Health Into Electronic Health Records by Cantor, Michael N, Thorpe, Lorna

“…As population health becomes more of a focus of health care, providers are realizing that data outside of traditional clinical findings can provide a broader…”
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Target of rapamycin (TOR) in nutrient signaling and growth control by Loewith, Robbie, Hall, Michael N

“…TOR (Target Of Rapamycin) is a highly conserved protein kinase that is important in both fundamental and clinical biology. In fundamental biology, TOR is a…”
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mTOR substrate phosphorylation in growth control by Battaglioni, Stefania, Benjamin, Don, Wälchli, Matthias, Maier, Timm, Hall, Michael N.

“…The target of rapamycin (TOR), discovered 30 years ago, is a highly conserved serine/threonine protein kinase that plays a central role in regulating cell…”
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A Neural Implementation of Wald’s Sequential Probability Ratio Test by Kira, Shinichiro, Yang, Tianming, Shadlen, Michael N.

“…Difficult decisions often require evaluation of samples of evidence acquired sequentially. A sensible strategy is to accumulate evidence, weighted by its…”
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Where is mTOR and what is it doing there? by Betz, Charles, Hall, Michael N

“…Target of rapamycin (TOR) forms two conserved, structurally distinct kinase complexes termed TOR complex 1 (TORC1) and TORC2. Each complex phosphorylates a…”
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Glutaminolysis Activates Rag-mTORC1 Signaling by Durán, Raúl V., Oppliger, Wolfgang, Robitaille, Aaron M., Heiserich, Lisa, Skendaj, Roswitha, Gottlieb, Eyal, Hall, Michael N.

“…Amino acids control cell growth via activation of the highly conserved kinase TORC1. Glutamine is a particularly important amino acid in cell growth control…”
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Activation of mTORC2 by Association with the Ribosome by Zinzalla, Vittoria, Stracka, Daniele, Oppliger, Wolfgang, Hall, Michael N.

“…The target of rapamycin (TOR) is a highly conserved protein kinase and a central controller of growth. Mammalian TOR complex 2 (mTORC2) regulates AGC kinase…”
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AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control by González, Asier, Hall, Michael N., Lin, Sheng-Cai, Hardie, D. Grahame

“…The AMPK (AMP-activated protein kinase) and TOR (target-of-rapamycin) pathways are interlinked, opposing signaling pathways involved in sensing availability of…”
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mTOR signaling in cellular and organismal energetics by Albert, Verena, Hall, Michael N

“…Mammalian TOR (mTOR) signaling controls growth, metabolism and energy homeostasis in a cell autonomous manner. Recent findings indicate that mTOR signaling in…”
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