Search Results - "Michael, K.E"

Current state of neuroprotective therapy using antibiotics in human traumatic brain injury and animal models by Ritter, Katharina, Somnuke, Pawit, Hu, Lingjiao, Griemert, Eva-Verena, Schäfer, Michael K E

“…TBI is a leading cause of death and disability in young people and older adults worldwide. There is no gold standard treatment for TBI besides surgical…”
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Low brain endocannabinoids associated with persistent non-goal directed nighttime hyperactivity after traumatic brain injury in mice by Vogel, Alexandra, Wilken-Schmitz, Annett, Hummel, Regina, Lang, Manuel, Gurke, Robert, Schreiber, Yannick, Schäfer, Michael K. E., Tegeder, Irmgard

“…Traumatic brain injury (TBI) is a frequent cause of chronic headache, fatigue, insomnia, hyperactivity, memory deficits, irritability and posttraumatic stress…”
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Sex-Dependent Regulation of Aromatase-Mediated Synaptic Plasticity in the Basolateral Amygdala by Bender, Roland A, Zhou, Lepu, Vierk, Ricardo, Brandt, Nicola, Keller, Alexander, Gee, Christine E, Schäfer, Michael K E, Rune, Gabriele M

“…The basolateral amygdala (BLA) integrates sensory input from cortical and subcortical regions, a function that requires marked synaptic plasticity. Here we…”
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Inhibition of spinal ferroptosis-like cell death alleviates hyperalgesia and spontaneous pain in a mouse model of bone cancer pain by Ding, Zhuofeng, Liang, Xiaoshen, Wang, Jian, Song, Zongbin, Guo, Qulian, Schäfer, Michael K.E., Huang, Changsheng

“…Bone cancer pain (BCP) impairs patients’ quality of life. However, the underlying mechanisms are still unclear. This study investigated the role of spinal…”
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NECAB family of neuronal calcium-binding proteins in health and disease by Bueno, Diones, Schäfer, Michael K E, Wang, Sudena, Schmeisser, Michael J, Methner, Axel

“…The N-terminal EF-hand calcium-binding proteins 1-3 (NECAB1-3) constitute a family of predominantly neuronal proteins characterized by the presence of at least…”
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Epileptiform activity interferes with proteolytic processing of Reelin required for dentate granule cell positioning by Tinnes, Stefanie, Schäfer, Michael K.E, Flubacher, Armin, Münzner, Gert, Frotscher, Michael, Haas, Carola A

“…The extracellular matrix protein Reelin is an essential regulator of neuronal migration and lamination in the developing and mature brain. Lack of Reelin…”
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Sortilin is dispensable for secondary injury processes following traumatic brain injury in mice by Staib-Lasarzik, Irina, Gölz, Christina, Bobkiewiecz, Wieslawa, Somnuke, Pawit, Sebastiani, Anne, Thal, Serge C., Schäfer, Michael K.E.

“…Traumatic brain injury (TBI) is characterized by complex secondary injury processes involving the p75 neurotrophin receptor (p75NTR), which has been proposed…”
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Role of L1CAM for axon sprouting and branching by Schäfer, Michael K. E., Frotscher, Michael

“…The central nervous system (CNS) has been traditionally considered as an organ that fails to regenerate in response to injury. Indeed, the lesioned CNS faces a…”
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L1 syndrome mutations impair neuronal L1 function at different levels by divergent mechanisms by Schäfer, Michael K.E, Nam, Yun-Chung, Moumen, Anice, Keglowich, Laura, Bouché, Elisabeth, Küffner, Mercedes, Bock, Hans H, Rathjen, Fritz G, Raoul, Cedric, Frotscher, Michael

“…Abstract Mutations in the human L1CAM gene cause neurodevelopmental disorders collectively referred to as L1 syndrome. Here, we investigated cellular…”
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The Charcot-Marie Tooth Disease Mutation R94Q in MFN2 Decreases ATP Production but Increases Mitochondrial Respiration under Conditions of Mild Oxidative Stress by Wolf, Christina, Zimmermann, Rahel, Thaher, Osamah, Bueno, Diones, Wüllner, Verena, Schäfer, Michael K E, Albrecht, Philipp, Methner, Axel

“…Charcot-Marie tooth disease is a hereditary polyneuropathy caused by mutations in Mitofusin-2 (MFN2), a GTPase in the outer mitochondrial membrane involved in…”
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Metareview of findings in Existing Literature reviews covering Behavioral Health-Physical Health Integration Studies by Keleti, D, Golinkoff, M, Weaver, K, Michael, K.E, Gelzer, A.D

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L1CAM ubiquitination facilitates its lysosomal degradation by Schäfer, Michael K.E., Schmitz, Brigitte, Diestel, Simone

“…The cell adhesion molecule L1 is implicated in several processes in the developing and adult nervous system. Intracellular trafficking of L1 is important for…”
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Multifaceted Interventions Improve Medication Adherence And Reduce Acute Hospitalization Rates In Medicaid Patients Prescribed Asthma Controllers by Gao, W, Keleti, D, Donia, T, Downey, T.W, Megargell, L, Kreitman, J, Michael, K.E, Gelzer, A.D

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Multifaceted Interventions Improve Medication Adherence In Medicaid Patients Prescribed Hypoglycemics, Statins, And/Or Antihypertensives by Gao, W, Keleti, D, Donia, T, Downey, T.W, Megargell, L, Kreitman, J, Michael, K.E, Gelzer, A.D

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The RGD integrin binding site in human L1-CAM is important for nuclear signaling by Gast, Daniela, Riedle, Svenja, Kiefel, Helena, Müerköster, Susanne Sebens, Schäfer, Heiner, Schäfer, Michael K.E., Altevogt, Peter

“…L1 cell adhesion molecule (L1-CAM) is a transmembrane cell adhesion molecule initially defined as a promigratory molecule in the developing nervous system. L1…”
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4 Your Kids Care: Reducing Non-Emergent Hospitalization In A Medicaid Pediatric Population Through Hands-On Training And Parent/Caregiver Education by Grant, M, Honeywell, A, Dinsmore, S, Keleti, D, Michael, K.E, Tan-Torres, S, Higgins, Y.L

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Moms2b: Improving Birth Outcomes Through Use Of Cell Phones, Texting, And Intensive Case Management by Grant, M, Stango, D.A, Anthony, D, Dinsmore, S, Keleti, D, Michael, K.E, Tan-Torres, S

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Drug Therapy Management Reduces Hospital Utilization And Costs In Patients With Diabetes Who Are High Medication Utilizers by Brophy, L, Williams, A, Keleti, D, Michael, K.E, Shepherd, M, Fox, S, Tan-Torres, S, Gelzer, A.D, Tegenu, M, Berman, E

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NG2/CSPG4 and progranulin in the posttraumatic glial scar by Schäfer, Michael K.E., Tegeder, Irmgard

“…Traumatic injury of the central nervous system is one of the leading causes of death and disability in young adults. Failure of regeneration is caused by…”
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Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice by Wang, Yong, Wernersbach, Isa, Strehle, Jenny, Li, Shuailong, Appel, Dominik, Klein, Matthias, Ritter, Katharina, Hummel, Regina, Tegeder, Irmgard, Schäfer, Michael K.E.

“…[Display omitted] •M/M attenuation does not affect early structural brain damage.•Early hematoma clearance is impaired by M/M attenuation.•IL-1β expression…”
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