Search Results - "Miazzi, Fabio"

Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors by Wicher, Dieter, Miazzi, Fabio

“…The majority of insect olfactory receptors belong to two distinct protein families, the ionotropic receptors (IRs), which are related to the ionotropic…”
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Targeting Insect Olfaction in vivo and in vitro Using Functional Imaging by Miazzi, Fabio, Jain, Kalpana, Kaltofen, Sabine, Bello, Jan E, Hansson, Bill S, Wicher, Dieter

“…Insects decode volatile chemical signals from its surrounding environment with the help of its olfactory system, in a fast and reliable manner for its…”
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The mouse receptor transporting protein RTP1S and the fly SNMP1 support the functional expression of the Drosophila odorant coreceptor Orco in mammalian culture cells by Halty-deLeon, Lorena, Miazzi, Fabio, Kaltofen, Sabine, Hansson, Bill S., Wicher, Dieter

“…•A new method enhances the expression of insect ORs in mammalian culture cells.•Drosophila Orco activity increases by coexpression with interacting…”
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Comparative toxicological assessment of cigarettes and new category products via an in vitro multiplex proteomics platform by Tsolakos, Nikos, Haswell, Linsey E., Miazzi, Fabio, Bishop, Emma, Antoranz, Asier, Pliaka, Vaia, Minia, Angeliki, Alexopoulos, Leonidas G., Gaca, Marianna, Breheny, Damien

“…Cigarette smoking is a risk factor for several diseases such as cancer, cardiovascular disease (CVD), and chronic obstructive pulmonary diseases (COPD),…”
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Evaluation of behavioural, chemical, toxicological and clinical studies of a tobacco heated product glo™ and the potential for bridging from a foundational dataset to new product iterations by Goodall, Sharon, Gale, Nathan, Thorne, David, Hadley, Simone, Prasad, Krishna, Gilmour, Ian, Miazzi, Fabio, Proctor, Christopher

“…Tobacco Heating Products (THPs) are tobacco products that heat rather than burn tobacco with temperatures less than 350 °C. Because of this operating…”
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Multi-endpoint in vitro toxicological assessment of snus and tobacco-free nicotine pouch extracts by Yu, Fan, Bishop, Emma, Miazzi, Fabio, Evans, Rhian, Smart, David, Breheny, Damien, Thorne, David

“…‘Modern’ oral tobacco-free nicotine pouches (NPs) are a nicotine containing product similar in appearance and concept to Swedish snus. A three-step approach…”
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Odor-induced cAMP production in Drosophila melanogaster olfactory sensory neurons by Miazzi, Fabio, Hansson, Bill S, Wicher, Dieter

“…Insect odorant receptors are seven transmembrane domain proteins that form cation channels, whose functional properties such as receptor sensitivity are…”
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Application of ToxTracker for the toxicological assessment of tobacco and nicotine delivery products by Smart, David E., Bozhilova, Stela, Miazzi, Fabio, Haswell, Linsey E., Gaca, Marianna D., Thorne, David, Breheny, Damien

“…[Display omitted] •ToxTracker enables quantification of toxicity across nicotine delivery product categories.•The biological response to extraction test matrix…”
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Optimization of Insect Odorant Receptor Trafficking and Functional Expression Via Transient Transfection in HEK293 Cells by Miazzi, Fabio, Hoyer, Carolin, Sachse, Silke, Knaden, Markus, Wicher, Dieter, Hansson, Bill S, Lavista-Llanos, Sofia

“…Insect odorant receptors (ORs) show a limited functional expression in various heterologous expression systems including insect and mammalian cells. This may…”
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Calmodulin modulates insect odorant receptor function by Mukunda, Latha, Miazzi, Fabio, Kaltofen, Sabine, Hansson, Bill S, Wicher, Dieter

“…Abstract Insect odorant receptors (ORs) are heteromeric complexes of an odor-specific receptor protein (OrX) and a ubiquitous co-receptor protein (Orco). The…”
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Low Ca2+ levels in the culture media support the heterologous expression of insect odorant receptor proteins in HEK cells by Miazzi, Fabio, Schulze, Hannes-Claudius, Zhang, Liwei, Kaltofen, Sabine, Hansson, Bill S., Wicher, Dieter

“…•Extracellular Ca2+ levels affect heterologous expression of insect ORs.•A reduced extracellular Ca2+ level increases the number of OR-expressing cells.•A low…”
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Calmodulin Affects Sensitization of Drosophila melanogaster Odorant Receptors by Mukunda, Latha, Miazzi, Fabio, Sargsyan, Vardanush, Hansson, Bill S, Wicher, Dieter

“…Flying insects have developed a remarkably sensitive olfactory system to detect faint and turbulent odor traces. This ability is linked to the olfactory…”
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Low Ca 2+ levels in the culture media support the heterologous expression of insect odorant receptor proteins in HEK cells by Miazzi, Fabio, Schulze, Hannes-Claudius, Zhang, Liwei, Kaltofen, Sabine, Hansson, Bill S, Wicher, Dieter

“…Heterologous expression of insect odorant receptors (ORs) in mammalian or insect cells is challenging due to the insufficient intracellular trafficking of ORs…”
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