Search Results - "Miazga, Agnieszka"

Myristoylated Derivatives of 2′,3′-didehydro-2′,3′-dideoxythymidine (stavudine) bi-Functional Prodrugs with Potent Anti-HIV-1 Activity and Low Cytotoxicity by Singh, Ramendra K, Miazga, Agnieszka, Dąbrowska, Aleksandra, Lipniacki, Andrzej, Piasek, Andrzej, Kulikowski, Tadeusz, Shugar, David

“…Background: To improve in vitro antiviral activity and selectivity of stavudine (d4T), a range of its bi-functional prodrugs, 5′-O-myristoylated derivatives,…”
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A mild and efficient approach to the 6H-oxazolo[3,2-f]pyrimidine-5,7-dione scaffold via unexpected rearrangement of 2,3-dihydropyrimido[6,1-b][1,5,3]dioxazepine-7,9(5H,8H)-diones: synthesis, crystallographic studies, and cytotoxic activity screening by Mieczkowski, Adam, Bazlekowa, Milena, Bagiński, Maciej, Wójcik, Jacek, Winczura, Alicja, Miazga, Agnieszka, Shahmoradi Ghahe, Somayeh, Gajda, Roman, Woźniak, Krzysztof, Tudek, Barbara

“…[Display omitted] We report a mild and efficient approach to the optically pure 6H-oxazolo[3,2-f]pyrimidine-5,7-dione scaffold via the unexpected rearrangement…”
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Partial selective inhibition of HIV-1 reverse transcriptase and human DNA polymerases I[sup3 and b by thiated 3a super(2)-fluorothymidine analogue 5a super(2)-triphosphates by Winska, Patrycja, Miazga, Agnieszka, Poznanski, Jaroslaw, Kulikowski, Tadeusz

“…3a super(2)-Deoxy-3a super(2)-fluorothymidine (FLT, alovudineA+) belongs to the most potent agents inhibiting HIV-1 replication. Its 5a super(2)-triphosphate…”
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Partial selective inhibition of HIV-1 reverse transcriptase and human DNA polymerases γ and β by thiated 3′-fluorothymidine analogue 5′-triphosphates by Wińska, Patrycja, Miazga, Agnieszka, Poznański, Jarosław, Kulikowski, Tadeusz

“…3′-Deoxy-3′-fluorothymidine (FLT, alovudine ®) belongs to the most potent agents inhibiting HIV-1 replication. Its 5′-triphosphate (FLTTP) is a potent…”
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Thiated derivatives of 2′,3′-dideoxy-3′-fluorothymidine: Synthesis, in vitro anti-HIV-1 activity and interaction with recombinant drug resistant HIV-1 reverse transcriptase forms by Miazga, Agnieszka, Hamy, François, Louvel, Séverine, Klimkait, Thomas, Pietrusiewicz, Zofia, Kurzyńska-Kokorniak, Anna, Figlerowicz, Marek, Wińska, Patrycja, Kulikowski, Tadeusz

“…Various thiated analogues of thymine 2′,3′-dideoxy-3′-fluoronucleoside (FLT) and their 5′-monophosphates and 5′-triphosphates were prepared with the use of…”
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Synthesis and anti-HIV properties of novel 6-phenylselenenyl-5-propyluracils by Miazga, Agnieszka, Felczak, Krzysztof, Siwecka, Maria A, Lipniacki, Andrzej, Piasek, Andrzej, Kulikowski, Tadeusz

“…Novel 6-phenylselenenyl-5-propyluracils were synthesized from 5-propyluracil with the use of regioselective synthesis to give…”
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5-Substituted N 4-Hydroxy-2‘-deoxycytidines and Their 5‘-Monophosphates:  Synthesis, Conformation, Interaction with Tumor Thymidylate Synthase, and in Vitro Antitumor Activity by Felczak, Krzysztof, Miazga, Agnieszka, Poznański, Jarosław, Bretner, Maria, Kulikowski, Tadeusz, Dzik, Jolanta M, Gołos, Barbara, Zieliński, Zbigniew, Cieśla, Joanna, Rode, Wojciech

“…Convenient procedures are described for the synthesis of 5-substituted N 4-hydroxy-2‘-deoxycytidines 5a,b,d − h via transformation of the respective…”
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Thiated Analogues of 2′,3′-Dideoxy-3′-fluorothymidine and Their Phosphorylated and Phosphonylated Derivatives: Synthesis, Interaction with HIV Reverse Transcriptase, and In Vitro Anti-HIV Activity by Miazga, A., Felczak, K., Bretner, M., Siwecka, M. A., Piasek, A., Kulikowski, T.

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5-Substituted N4-Hydroxy-2‘-deoxycytidines and Their 5‘-Monophosphates:  Synthesis, Conformation, Interaction with Tumor Thymidylate Synthase, and in Vitro Antitumor Activity by FELCZAK, Krzysztof, MIAZGA, Agnieszka, POZNAńSKI, Jarosław, BRETNER, Maria, KULIKOWSKI, Tadeusz, DZIK, Jolanta M., GOłOS, Barbara, ZIELIńSKI, Zbigniew, CIEśLA, Joanna, RODE, Wojciech

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