Search Results - "Miao, Xiaokang"
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Study of WO3/Pt hydrogen sensitive film fabricated by Sol-Gel method
Published in Optik (Stuttgart) (01-12-2022)“…Pt-doped WO3 materials have good hydrogen-sensing properties, which are widely used in the field of hydrogen sensing. In this paper, Sol-Gel method is used to…”
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2
p53 as a double-edged sword in the progression of non-alcoholic fatty liver disease
Published in Life sciences (1973) (15-12-2018)“…Non-alcoholic fatty liver disease (NAFLD) derives from the accumulation of hepatic lipids, which leads to liver steatosis and then triggers non-alcoholic…”
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Novel Feleucin-K3-Derived Peptides Modified with Sulfono-γ-AA Building Blocks Targeting Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus Infections
Published in Journal of medicinal chemistry (26-01-2023)“…The prevalence of multidrug-resistant bacterial infections has led to dramatically increased morbidity and mortality. Antimicrobial peptides (AMPs) have great…”
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Site-Selective Polyfluoroaryl Modification and Unsymmetric Stapling of Unprotected Peptides
Published in Journal of the American Chemical Society (13-03-2024)“…Peptide stapling is recognized as an effective strategy for improving the proteolytic stability and cell permeability of peptides. In this study, we present a…”
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Novel antimicrobial peptides modified with fluorinated sulfono-γ-AA having high stability and targeting multidrug-resistant bacteria infections
Published in European journal of medicinal chemistry (15-01-2024)“…The emergence and increasing prevalence of multidrug-resistant (MDR) bacteria have posed an urgent demand for novel antibacterial drugs. Currently,…”
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The novel peptide DR4penA attenuates the bleomycin‐ and paraquat‐induced pulmonary fibrosis by suppressing the TGF‐β/Smad signaling pathway
Published in The FASEB journal (01-11-2023)“…Pulmonary fibrosis (PF), which is caused by continuous alveolar epithelial cell injury and abnormal repair, is referred to as a difficult disease of the lung…”
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The Peptide DH α -(4-pentenyl)-ANPQIR-NH 2 Exhibits Antifibrotic Activity in Multiple Pulmonary Fibrosis Models Induced by Particulate and Soluble Chemical Fibrogenic Agents
Published in The Journal of pharmacology and experimental therapeutics (01-02-2024)“…Interstitial lung diseases (ILDs) are a group of restrictive lung diseases characterized by interstitial inflammation and pulmonary fibrosis. The incidence of…”
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Enhanced cell selectivity of hybrid peptides with potential antimicrobial activity and immunomodulatory effect
Published in Biochimica et biophysica acta. General subjects (01-04-2020)“…Hybridization is a useful strategy to bond the advantages of different peptides into novel constructions. We designed a series of AMPs based on the structures…”
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Novel antimicrobial peptide CPF‐C1 analogs with superior stabilities and activities against multidrug‐resistant bacteria
Published in Chemical biology & drug design (01-11-2017)“…As numerous clinical isolates are resistant to most conventional antibiotics, infections caused by multidrug‐resistant bacteria are associated with a higher…”
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Neurokinin-1 receptor mediated breast cancer cell migration by increased expression of MMP-2 and MMP-14
Published in European journal of cell biology (01-10-2016)“…Breast cancer (BC) is a common reason of cancer-associated death in female. To develop novel strategy of therapeutics, it is crucial to comprehensively…”
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Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors
Published in Peptides (New York, N.Y. : 1980) (01-09-2016)“…•Human hemokinin-1 (hHK-1) induced breast cancer cells migration via NK1 receptor.•HHK-1 increased the expression level of MMP-2 and MMP-14 which were…”
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Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis
Published in ACS pharmacology & translational science (12-04-2024)“…Renal fibrosis is a complex pathological process that contributes to the development of chronic kidney disease due to various risk factors. Conservative…”
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