Search Results - "Miao, Chensi"

Systematically investigating the key features of the DNase deactivated Cpf1 for tunable transcription regulation in prokaryotic cells by Miao, Chensi, Zhao, Huiwei, Qian, Long, Lou, Chunbo

“…With a unique crRNA processing capability, the CRISPR associated Cpf1 protein holds great potential for multiplex gene regulation. Unlike the well-studied Cas9…”
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Protein language models-assisted optimization of a uracil-N-glycosylase variant enables programmable T-to-G and T-to-C base editing by He, Yan, Zhou, Xibin, Chang, Chong, Chen, Ge, Liu, Weikuan, Li, Geng, Fan, Xiaoqi, Sun, Mingsun, Miao, Chensi, Huang, Qianyue, Ma, Yunqing, Yuan, Fajie, Chang, Xing

“…Current base editors (BEs) use DNA deaminases, including cytidine deaminase in cytidine BE (CBE) or adenine deaminase in adenine BE (ABE), to facilitate…”
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Engineering the Ultrasensitive Transcription Factors by Fusing a Modular Oligomerization Domain by Hou, Junran, Zeng, Weiqian, Zong, Yeqing, Chen, Zehua, Miao, Chensi, Wang, Baojun, Lou, Chunbo

“…The dimerization and high-order oligomerization of transcription factors has endowed them with cooperative regulatory capabilities that play important roles in…”
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Abstract 4999: Characterization of myeloid derived suppressor cells after capecitabine and nivolumab combination treatment by Lin, Qing, Wang, Tienan, Yan, Wenjun, Wu, Ranran, Nie, Lun, Miao, Chensi, Wang, Xing, Wang, Feng, Zhang, Jie, Shi, Weilin, Yuan, Yanping, Shi, Tingting, Li, Ao, Dong, Wei, Chen, Xu, Sun, Jingying, Ji, Qunsheng

“…Abstract Capecitabine, a widely used oral chemotherapeutic agent, only functions in its active form, 5-FU. The metabolism of capecitabine to 5-FU frequently…”
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Engineering Translational Activators with CRISPR-Cas System by Du, Pei, Miao, Chensi, Lou, Qiuli, Wang, Zefeng, Lou, Chunbo

“…RNA parts often serve as critical components in genetic engineering. Here we report a design of translational activators which is composed of an RNA…”
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为有效防控新冠病毒肺炎争取时间——抗疫假期政策对疫情传播的影响 by 陈思邈, 陈秋实, 杨维中, 薛澜, 刘远立, 杨俊涛, 王辰, TillB?rnighausen

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