Search Results - "Mian, Yousaf A"

MicroRNAs in leukemias: emerging diagnostic tools and therapeutic targets by Mian, Yousaf A, Zeleznik-Le, Nancy J

“…MicroRNAs (miRNA) are small non-coding RNAs of approximately 22 nucleotides that regulate the translation and stability of mRNA to control different functions…”
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The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1 by Mian, Yousaf A, Zeleznik-Le, Nancy J

“…Graphical abstract…”
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The Mir-17-92 Cluster Contributes to MLL Leukemia through the Repression of PKNOX1, a MEIS1 Competitor by Mian, Yousaf A, Zeleznik-Le, Nancy J.

“…Leukemias which arise as a result of translocations between the MLL gene and one of more than 80 different partner genes have a relatively poor prognosis. As a…”
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Development of Cirmtuzumab Antibody-Drug Conjugates (ADCs) Targeting Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1) by Mian, Yousaf A., Widhopf II, George F., Vo, Thanh-Trang, Jessen, Katti, Rassenti, Laura Z., Kipps, Thomas J.

“…ROR1 is an onco-embryonic surface antigen expressed on chronic lymphocytic leukemia (CLL) and a variety of other cancers, but not on most normal adult tissues…”
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The miR-17 similar to 92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1 by Miana, Yousaf A, Zeleznik-Lea, Nancy J

“…Mixed lineage leukemias have a relatively poor prognosis and arise as a result of translocations between the MLL(KMT2A) gene and one of multiple partner genes…”
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