Search Results - "Mian, Muhammad Oneeb Rehman"
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Long-Term Impact of Preterm Birth: Neurodevelopmental and Physical Health Outcomes
Published in Clinics in perinatology (01-06-2017)“…Preterm birth severely disrupts the normal developmental maturation of organ systems, resulting in lasting adverse effects. High blood pressure, cardiac…”
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Endothelin-1 Overexpression Exacerbates Atherosclerosis and Induces Aortic Aneurysms in Apolipoprotein E Knockout Mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2013)“…OBJECTIVE—Endothelin (ET)-1 plays a role in vascular reactive oxygen species production and inflammation. ET-1 has been implicated in human atherosclerosis and…”
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Innate Immunity in Hypertension
Published in Current hypertension reports (01-02-2014)“…Despite intensive research, the exact cause of hypertension remains unknown. Low-grade inflammation has been proposed to play a key role in the pathogenesis of…”
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Left Ventricle Structure and Function in Young Adults Born Very Preterm and Association with Neonatal Characteristics
Published in Journal of clinical medicine (18-04-2021)“…Preterm birth increases risk of cardiovascular disease and early death. A body of evidence suggests left ventricle (LV) echocardiographic alterations in…”
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Long-Term Impact of Preterm Birth
Published in Clinics in perinatology (01-06-2017)“…Preterm birth severely disrupts the normal developmental maturation of organ systems, resulting in lasting adverse effects. High blood pressure, cardiac…”
Get full text
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Across the globe in 4 months: two International Society of Hypertension new investigator symposia in 2014
Published in Journal of hypertension (01-04-2015)Get full text
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Deficiency of T-regulatory cells exaggerates angiotensin II-induced microvascular injury by enhancing immune responses
Published in Journal of hypertension (01-01-2016)“…AIMS:T-regulatory lymphocyte (Treg) adoptive transfer prevented angiotensin (Ang) II-induced hypertension and microvascular injury. Scurfy mice are deficient…”
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γδ T Cells Mediate Angiotensin II-Induced Hypertension and Vascular Injury
Published in Circulation (New York, N.Y.) (30-05-2017)“…BACKGROUND:Innate antigen-presenting cells and adaptive immune T cells have been implicated in the development of hypertension. However, the T-lymphocyte…”
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Endothelin-1 Overexpression Exaggerates Diabetes-Induced Endothelial Dysfunction by Altering Oxidative Stress
Published in American journal of hypertension (01-11-2016)“…BACKGROUND Increased endothelin (ET)-1 expression causes endothelial dysfunction and oxidative stress. Plasma ET-1 is increased in patients with diabetes…”
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Kidney Size, Renal Function, Ang (Angiotensin) Peptides, and Blood Pressure in Young Adults Born Preterm: The HAPI Study
Published in Hypertension (Dallas, Tex. 1979) (01-10-2018)“…Preterm birth incurs a higher risk for adult cardiovascular diseases, including hypertension. Because preterm birth may impact nephrogenesis, study objectives…”
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Dual opposing roles of adaptive immunity in hypertension
Published in European heart journal (14-05-2014)“…Hypertension involves remodelling and inflammation of the arterial wall. Interactions between vascular and inflammatory cells play a critical role in disease…”
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TLR (Toll-Like Receptor) 4 Antagonism Prevents Left Ventricular Hypertrophy and Dysfunction Caused by Neonatal Hyperoxia Exposure in Rats
Published in Hypertension (Dallas, Tex. 1979) (01-10-2019)“…Preterm birth is associated with proinflammatory conditions and alterations in adult cardiac shape and function. Neonatal exposure to high oxygen, a rat model…”
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Matrix metalloproteinase-2 knockout prevents angiotensin II-induced vascular injury
Published in Cardiovascular research (01-12-2017)“…Matrix metalloproteinases (MMPs) have been implicated in the development of hypertension in animal models and humans. Mmp2 deletion did not change Ang…”
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Increased Incidence but Lack of Association Between Cardiovascular Risk Factors in Adults Born Preterm
Published in Hypertension (Dallas, Tex. 1979) (01-03-2020)“…Preterm birth incurs an increased risk of early cardiovascular events and death. In the general population, cardiovascular risk factors cluster in the context…”
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Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors
Published in Hypertension (Dallas, Tex. 1979) (01-05-2016)“…We investigated the role of angiotensin type 1a receptors (AGTR1a) in vascular injury induced by aldosterone activation of mineralocorticoid receptors in…”
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Abstract 050: TLR4 Antagonism Prevents Early Left Ventricular Hypertrophy and Dysfunction Associated With Neonatal Hyperoxia Exposure
Published in Hypertension (Dallas, Tex. 1979) (01-09-2017)“…Abstract only Objective: Preterm birth is associated with proinflammatory conditions early in life. Our lab has shown in rats that transient neonatal exposure…”
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Abstract P617: Angiotensin II-induced Hypertension And Vascular Injury Is Mediated By Gamma/delta T Cells
Published in Hypertension (Dallas, Tex. 1979) (01-09-2015)“…Abstract only Objective: Both innate antigen presenting cells and the adaptive immune system have been shown to play a role in the development of hypertension…”
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Abstract P146: Transient Neonatal High Oxygen Exposure Accelerates Adult Cardiac Baseline and Ang Ii-induced Prooxidative and Proinflammatory Responses
Published in Hypertension (Dallas, Tex. 1979) (01-09-2016)“…Abstract only Objective: Preterm birth is associated with disequilibrated early life oxidant-antioxidant and proinflammatory conditions that can be carried…”
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Abstract P138: Alterations in Cardiac Structure and Function in Young Adults Born Extremely Preterm: Impact of Neonatal Bronchopulmonary Dysplasia
Published in Hypertension (Dallas, Tex. 1979) (01-09-2017)“…Abstract only Objective: Studies support a causal association between preterm birth and increased risk of cardiovascular diseases. Increased left and right…”
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