Kinetic study of acid-soluble DNA formation under the effect of DNase I

A mathematical model of acid-soluble DNA formation under the effect of DNase I was developed. The data from the kinetic analysis suggest that at the stage of 10-60% solubilization the number of breaks in DNA single strands seem to be linearly dependent on the increment of acid-soluble DNA. This stag...

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Bibliographic Details
Published in:	Ukrainskij biohimičeskij žurnal Vol. 52; no. 3; p. 369
Main Authors:	Fedorova, T M, Miakisheva, V P, Grabarev, S P, Ryskukova, L N
Format:	Journal Article
Language:	Russian
Published:	Ukraine 01-05-1980
Subjects:	Deoxyribonuclease I Deoxyribonucleases - metabolism DNA - biosynthesis Endonucleases - metabolism Kinetics Mathematics
Online Access:	Get more information
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Summary:	A mathematical model of acid-soluble DNA formation under the effect of DNase I was developed. The data from the kinetic analysis suggest that at the stage of 10-60% solubilization the number of breaks in DNA single strands seem to be linearly dependent on the increment of acid-soluble DNA. This stage of acid-soluble DNA formation may be interpreted in terms of the monomolecular (pseudomonomolecular) reaction.
ISSN:	0201-8470