Search Results - "Mižíková, Ivana"

A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency by Kang, Martin H., van Lieshout, Laura P., Xu, Liqun, Domm, Jakob M., Vadivel, Arul, Renesme, Laurent, Mühlfeld, Christian, Hurskainen, Maria, Mižíková, Ivana, Pei, Yanlong, van Vloten, Jacob P., Thomas, Sylvia P., Milazzo, Claudia, Cyr-Depauw, Chanèle, Whitsett, Jeffrey A., Nogee, Lawrence M., Wootton, Sarah K., Thébaud, Bernard

“…Surfactant protein B (SP-B) deficiency is an autosomal recessive disorder that impairs surfactant homeostasis and manifests as lethal respiratory distress. A…”
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Looking ahead: where to next for animal models of bronchopulmonary dysplasia? by Nardiello, Claudio, Mižíková, Ivana, Morty, Rory E.

“…Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth, with appreciable morbidity and mortality in a neonatal intensive care…”
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Recent advances in late lung development and the pathogenesis of bronchopulmonary dysplasia by Madurga, Alicia, Mizíková, Ivana, Ruiz-Camp, Jordi, Morty, Rory E

“…In contrast to early lung development, a process exemplified by the branching of the developing airways, the later development of the immature lung remains…”
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Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage by Hurskainen, Maria, Mižíková, Ivana, Cook, David P., Andersson, Noora, Cyr-Depauw, Chanèle, Lesage, Flore, Helle, Emmi, Renesme, Laurent, Jankov, Robert P., Heikinheimo, Markku, Vanderhyden, Barbara C., Thébaud, Bernard

“…During late lung development, alveolar and microvascular development is finalized to enable sufficient gas exchange. Impaired late lung development manifests…”
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Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasia by Nardiello, Claudio, Mižíková, Ivana, Silva, Diogo M, Ruiz-Camp, Jordi, Mayer, Konstantin, Vadász, István, Herold, Susanne, Seeger, Werner, Morty, Rory E

“…Progress in developing new therapies for bronchopulmonary dysplasia (BPD) is sometimes complicated by the lack of a standardised animal model. Our objective…”
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Collagen and elastin cross-linking is altered during aberrant late lung development associated with hyperoxia by Mižíková, Ivana, Ruiz-Camp, Jordi, Steenbock, Heiko, Madurga, Alicia, Vadász, István, Herold, Susanne, Mayer, Konstantin, Seeger, Werner, Brinckmann, Jürgen, Morty, Rory E

“…Maturation of the lung extracellular matrix (ECM) plays an important role in the formation of alveolar gas exchange units. A key step in ECM maturation is…”
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Lysyl Oxidases Play a Causal Role in Vascular Remodeling in Clinical and Experimental Pulmonary Arterial Hypertension by Nave, Alexander H, Mižíková, Ivana, Niess, Gero, Steenbock, Heiko, Reichenberger, Frank, Talavera, María L, Veit, Florian, Herold, Susanne, Mayer, Konstantin, Vadász, István, Weissmann, Norbert, Seeger, Werner, Brinckmann, Jürgen, Morty, Rory E

“…OBJECTIVE—Pulmonary vascular remodeling, the pathological hallmark of pulmonary arterial hypertension, is attributed to proliferation, apoptosis resistance,…”
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Characterization of the innate immune response in a novel murine model mimicking bronchopulmonary dysplasia by Cyr-Depauw, Chanèle, Hurskainen, Maria, Vadivel, Arul, Mižíková, Ivana, Lesage, Flore, Thébaud, Bernard

“…Background Bronchopulmonary dysplasia (BPD), the most common complication of prematurity, arises from various factors that compromise lung development,…”
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Stereological monitoring of mouse lung alveolarization from the early postnatal period to adulthood by Pozarska, Agnieszka, Rodríguez-Castillo, José Alberto, Surate Solaligue, David E, Ntokou, Aglaia, Rath, Philipp, Mižíková, Ivana, Madurga, Alicia, Mayer, Konstantin, Vadász, István, Herold, Susanne, Ahlbrecht, Katrin, Seeger, Werner, Morty, Rory E

“…Postnatal lung maturation generates a large number of small alveoli, with concomitant thinning of alveolar septal walls, generating a large gas exchange…”
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Systemic hydrogen sulfide administration partially restores normal alveolarization in an experimental animal model of bronchopulmonary dysplasia by Madurga, Alicia, Mižíková, Ivana, Ruiz-Camp, Jordi, Vadász, István, Herold, Susanne, Mayer, Konstantin, Fehrenbach, Heinz, Seeger, Werner, Morty, Rory E

“…Arrested alveolarization is the pathological hallmark of bronchopulmonary dysplasia (BPD), a complication of premature birth. Here, the impact of systemic…”
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Minoxidil Cannot Be Used To Target Lysyl Hydroxylases during Postnatal Mouse Lung Development: A Cautionary Note by Pfeffer, Tilman, Lignelli, Ettore, Inoue, Hajime, Mižíková, Ivana, Surate Solaligue, David E, Steenbock, Heiko, Myti, Despoina, Vadász, István, Herold, Susanne, Seeger, Werner, Brinckmann, Jürgen, Morty, Rory E

“…The lysyl hydroxylases (procollagen-lysine 5-dioxygenases) PLOD1, PLOD2, and PLOD3 have been proposed as pathogenic mediators of stunted lung development in…”
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The Extracellular Matrix in Bronchopulmonary Dysplasia: Target and Source by Mižíková, Ivana, Morty, Rory E

“…Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth that contributes significantly to morbidity and mortality in neonatal intensive care…”
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Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts by Mižíková, Ivana, Palumbo, Francesco, Tábi, Tamás, Herold, Susanne, Vadász, István, Mayer, Konstantin, Seeger, Werner, Morty, Rory E

“…Lysyl oxidases are credited with pathogenic roles in lung diseases, including cancer, fibrosis, pulmonary hypertension, congenital diaphragmatic hernia, and…”
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Targeting miR‐34a/Pdgfra interactions partially corrects alveologenesis in experimental bronchopulmonary dysplasia by Ruiz‐Camp, Jordi, Quantius, Jennifer, Lignelli, Ettore, Arndt, Philipp F, Palumbo, Francesco, Nardiello, Claudio, Surate Solaligue, David E, Sakkas, Elpidoforos, Mižíková, Ivana, Rodríguez‐Castillo, José Alberto, Vadász, István, Richardson, William D, Ahlbrecht, Katrin, Herold, Susanne, Seeger, Werner, Morty, Rory E

“…Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth characterized by arrested lung alveolarization, which generates lungs that are…”
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Single-Cell RNA Sequencing-Based Characterization of Resident Lung Mesenchymal Stromal Cells in Bronchopulmonary Dysplasia by Mižíková, Ivana, Lesage, Flore, Cyr-Depauw, Chanele, Cook, David P, Hurskainen, Maria, Hänninen, Satu M, Vadivel, Arul, Bardin, Pauline, Zhong, Shumei, Carpén, Olli, Vanderhyden, Barbara C, Thébaud, Bernard

“…Late lung development is a period of alveolar and microvascular formation, which is pivotal in ensuring sufficient and effective gas exchange. Defects in late…”
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A comparison of airway pressures for inflation fixation of developing mouse lungs for stereological analyses by Pérez-Bravo, David, Myti, Despoina, Mižíková, Ivana, Pfeffer, Tilman, Surate Solaligue, David E., Nardiello, Claudio, Vadász, István, Herold, Susanne, Seeger, Werner, Ahlbrecht, Katrin, Morty, Rory E.

“…The morphometric analysis of lung structure using the principles of stereology has emerged as a powerful tool to describe the structural changes in lung…”
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The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization by Madurga, Alicia, Golec, Anita, Pozarska, Agnieszka, Ishii, Isao, Mižíková, Ivana, Nardiello, Claudio, Vadász, István, Herold, Susanne, Mayer, Konstantin, Reichenberger, Frank, Fehrenbach, Heinz, Seeger, Werner, Morty, Rory E

“…The gasotransmitter hydrogen sulfide (H2S) is emerging as a mediator of lung physiology and disease. Recent studies revealed that H2S administration limited…”
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Transmission of microRNA antimiRs to mouse offspring via the maternal-placental-fetal unit by Hönig, Jonas, Mižíková, Ivana, Nardiello, Claudio, Surate Solaligue, David E, Daume, Maximilian J, Vadász, István, Mayer, Konstantin, Herold, Susanne, Günther, Stefan, Seeger, Werner, Morty, Rory E

“…The emergence of microRNA as regulators of organogenesis and tissue differentiation has stimulated interest in the ablation of microRNA expression and function…”
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Caffeine administration modulates TGF-β signaling but does not attenuate blunted alveolarization in a hyperoxia-based mouse model of bronchopulmonary dysplasia by Rath, Philipp, Nardiello, Claudio, Surate Solaligue, David E., Agius, Ronald, Mižíková, Ivana, Hühn, Sebastian, Mayer, Konstantin, Vadász, István, Herold, Susanne, Runkel, Frank, Seeger, Werner, Morty, Rory E.

“…Background: Caffeine is widely used to manage apnea of prematurity, and reduces the incidence of bronchopulmonary dysplasia (BPD). Deregulated transforming…”
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Targeting transglutaminase 2 partially restores extracellular matrix structure but not alveolar architecture in experimental bronchopulmonary dysplasia by Mižíková, Ivana, Pfeffer, Tilman, Nardiello, Claudio, Surate Solaligue, David E., Steenbock, Heiko, Tatsukawa, Hideki, Silva, Diogo M., Vadász, István, Herold, Susanne, Pease, Richard J., Iismaa, Siiri E., Hitomi, Kiyotaka, Seeger, Werner, Brinckmann, Jürgen, Morty, Rory E.

“…The generation, maturation and remodelling of the extracellular matrix (ECM) are essential for the formation of alveoli during lung development. Alveoli…”
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