Search Results - "Miñán, Ana Fernández"

The cellular landscape of the endochondral bone during the transition to extrauterine life by Rueda, Alejandro Díaz, Salvador-Martínez, Irepan, Sospedra-Arrufat, Ismael, Alcaina-Caro, Ana, Fernández-Miñán, Ana, Burgos-Ruiz, Ana M, Cases, Ildefonso, Mohedano, Alberto, Tena, Juan J, Heyn, Holger, Lopez-Rios, Javier, Nusspaumer, Gretel

“…The cellular complexity of the endochondral bone underlies its essential and pleiotropic roles during organismal life. While the adult bone has received…”
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Zebrafish enhancer detection (ZED) vector: A new tool to facilitate transgenesis and the functional analysis of cis‐regulatory regions in zebrafish by Bessa, José, Tena, Juan J., de la Calle‐Mustienes, Elisa, Fernández‐Miñán, Ana, Naranjo, Silvia, Fernández, Almudena, Montoliu, Lluis, Akalin, Altuna, Lenhard, Boris, Casares, Fernando, Gómez‐Skarmeta, José Luis

“…The identification and characterization of the regulatory activity of genomic sequences is crucial for understanding how the information contained in genomes…”
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Jak/Stat signalling in niche support cells regulates dpp transcription to control germline stem cell maintenance in the Drosophila ovary by Lourdes López-Onieva, Ana Fernández-Miñán, Acaimo González-Reyes

“…The existence of specialised regulatory microenvironments or niches that sustain stable stem cell populations is well documented in many tissues. However, the…”
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The developmental epigenomics toolbox: ChIP-seq and MethylCap-seq profiling of early zebrafish embryos by Bogdanović, Ozren, Fernández-Miñán, Ana, Tena, Juan J., de la Calle-Mustienes, Elisa, Gómez-Skarmeta, José Luis

“…Genome-wide profiling of DNA methylation and histone modifications answered many questions as to how the genes are regulated on a global scale and what their…”
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Comparative epigenomics in distantly related teleost species identifies conserved cis-regulatory nodes active during the vertebrate phylotypic period by Tena, Juan J, González-Aguilera, Cristina, Fernández-Miñán, Ana, Vázquez-Marín, Javier, Parra-Acero, Helena, Cross, Joe W, Rigby, Peter W J, Carvajal, Jaime J, Wittbrodt, Joachim, Gómez-Skarmeta, José L, Martínez-Morales, Juan R

“…The complex relationship between ontogeny and phylogeny has been the subject of attention and controversy since von Baer's formulations in the 19th century…”
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Identification and analysis of conserved cis-regulatory regions of the MEIS1 gene by Royo, José Luis, Bessa, José, Hidalgo, Carmen, Fernández-Miñán, Ana, Tena, Juan J, Roncero, Yolanda, Gómez-Skarmeta, José Luis, Casares, Fernando

“…Meis1, a conserved transcription factor of the TALE-homeodomain class, is expressed in a wide variety of tissues during development. Its complex expression…”
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The Ste20 kinase misshapen is essential for the invasive behaviour of ovarian epithelial cells in Drosophila by Cobreros-Reguera, Laura, Fernández-Miñán, Ana, Fernández-Espartero, Cecilia H, López-Schier, Hernán, González-Reyes, Acaimo, Martín-Bermudo, María D

“…Stationary‐to‐migratory transitions of epithelial cells have a key role in development and tumour progression. Border cell migration is a powerful system in…”
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MIR retrotransposon sequences provide insulators to the human genome by Wang, Jianrong, Vicente-García, Cristina, Seruggia, Davide, Moltó, Eduardo, Fernandez-Miñán, Ana, Neto, Ana, Lee, Elbert, Gómez-Skarmeta, José Luis, Montoliu, Lluís, Lunyak, Victoria V., Jordan, I. King

“…Insulators are regulatory elements that help to organize eukaryotic chromatin via enhancer-blocking and chromatin barrier activity. Although there are several…”
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Dynamics of enhancer chromatin signatures mark the transition from pluripotency to cell specification during embryogenesis by Bogdanovic, Ozren, Fernandez-Miñán, Ana, Tena, Juan J, de la Calle-Mustienes, Elisa, Hidalgo, Carmen, van Kruysbergen, Ila, van Heeringen, Simon J, Veenstra, Gert Jan C, Gómez-Skarmeta, José Luis

“…The generation of distinctive cell types that form different tissues and organs requires precise, temporal and spatial control of gene expression. This depends…”
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Boundary sequences flanking the mouse tyrosinase locus ensure faithful pattern of gene expression by Seruggia, Davide, Fernández, Almudena, Cantero, Marta, Fernández-Miñán, Ana, Gomez-Skarmeta, José Luis, Pelczar, Pawel, Montoliu, Lluis

“…Control of gene expression is dictated by cell-type specific regulatory sequences that physically organize the structure of chromatin, including promoters,…”
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Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP by Aguirre, Luis A, Alonso, M Eva, Badía-Careaga, Claudio, Rollán, Isabel, Arias, Cristina, Fernández-Miñán, Ana, López-Jiménez, Elena, Aránega, Amelia, Gómez-Skarmeta, José Luis, Franco, Diego, Manzanares, Miguel

“…Recent genome-wide association studies have uncovered genomic loci that underlie an increased risk for atrial fibrillation, the major cardiac arrhythmia in…”
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Numb/Numbl-Opo Antagonism Controls Retinal Epithelium Morphogenesis by Regulating Integrin Endocytosis by Bogdanović, Ozren, Delfino-Machín, Mariana, Nicolás-Pérez, María, Gavilán, María P., Gago-Rodrigues, Inês, Fernández-Miñán, Ana, Lillo, Concepción, Ríos, Rosa M., Wittbrodt, Joachim, Martínez-Morales, Juan R.

“…Polarized trafficking of adhesion receptors plays a pivotal role in controlling cellular behavior during morphogenesis. Particularly, clathrin-dependent…”
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Profiling of conserved non-coding elements upstream of SHOX and functional characterisation of the SHOX cis-regulatory landscape by Verdin, Hannah, Fernández-Miñán, Ana, Benito-Sanz, Sara, Janssens, Sandra, Callewaert, Bert, De Waele, Kathleen, De Schepper, Jean, François, Inge, Menten, Björn, Heath, Karen E., Gómez-Skarmeta, José Luis, De Baere, Elfride

“…Genetic defects such as copy number variations (CNVs) in non-coding regions containing conserved non-coding elements (CNEs) outside the transcription unit of…”
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Integrin Signaling Regulates Spindle Orientation in Drosophila to Preserve the Follicular-Epithelium Monolayer by Fernández-Miñán, Ana, Martín-Bermudo, María D., González-Reyes, Acaimo

“…Epithelia act as important physiological barriers and as structural components of tissues and organs. In the Drosophila ovary, follicle cells envelop the…”
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Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis by Gago-Rodrigues, Ines, Fernández-Miñán, Ana, Letelier, Joaquin, Naranjo, Silvia, Tena, Juan J., Gómez-Skarmeta, José L., Martinez-Morales, Juan R.

“…The self-organized morphogenesis of the vertebrate optic cup entails coupling the activation of the retinal gene regulatory network to the constriction-driven…”
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Trap-TRAP, a Versatile Tool for Tissue-Specific Translatomics in Zebrafish by Corbacho, Jorge, Sanabria-Reinoso, Estefanía, Buono, Lorena, Fernández-Miñan, Ana, Martínez-Morales, Juan R

“…Developmental and physiological processes depend on the transcriptional and translational activity of heterogeneous cell populations. A main challenge in gene…”
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A role for insulator elements in the regulation of gene expression response to hypoxia by Tiana, Maria, Villar, Diego, Pérez-Guijarro, Eva, Gómez-Maldonado, Laura, Moltó, Eduardo, Fernández-Miñán, Ana, Gómez-Skarmeta, Jose Luis, Montoliu, Lluís, del Peso, Luis

“…Hypoxia inducible factor (HIF) up-regulates the transcription of a few hundred genes required for the adaptation to hypoxia. This restricted set of targets is…”
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Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes by Casares, Fernando, Gómez-Skarmeta, José Luis, Martin, David, Pantoja, Cristina, Miñán, Ana Fernández, Valdes-Quezada, Christian, Moltó, Eduardo, Matesanz, Fuencisla, Bogdanović, Ozren, de la Calle-Mustienes, Elisa, Domínguez, Orlando, Taher, Leila, Furlan-Magaril, Mayra, Alcina, Antonio, Cañón, Susana, Fedetz, María, Blasco, María A, Pereira, Paulo S, Ovcharenko, Ivan, Recillas-Targa, Félix, Montoliu, Lluís, Manzanares, Miguel, Guigó, Roderic, Serrano, Manuel

“…Identifying genes associated with SNPs in non-coding regions is difficult as the SNPs are often located far from the promoters they impact. Cross-species…”
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Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints by Irimia, Manuel, Tena, Juan J, Alexis, Maria S, Fernandez-Miñan, Ana, Maeso, Ignacio, Bogdanovic, Ozren, de la Calle-Mustienes, Elisa, Roy, Scott W, Gómez-Skarmeta, José L, Fraser, Hunter B

“…The order of genes in eukaryotic genomes has generally been assumed to be neutral, since gene order is largely scrambled over evolutionary time. Only a handful…”
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A role for the chaperone Hsp70 in the regulation of border cell migration in the Drosophila ovary by Cobreros, Laura, Fernández-Miñán, Ana, Luque, Carlos M., González-Reyes, Acaimo, Martín-Bermudo, María D.

“…Unravelling the molecular mechanisms that govern cell migration is of great importance towards understanding both normal embryogenesis and physiological and…”
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