Search Results - "Mi, Xuenan"

MicroRNA‐216a induces endothelial senescence and inflammation via Smad3/IκBα pathway by Yang, Shujun, Mi, Xuenan, Chen, Yu, Feng, Congrui, Hou, Zhihui, Hui, Rutai, Zhang, Weili

“…Vascular endothelial senescence contributes to atherosclerosis and coronary artery disease (CAD), but the mechanisms are yet to be clarified. We identified…”
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Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis by D’Alessandro-Gabazza, Corina N., Yasuma, Taro, Kobayashi, Tetsu, Toda, Masaaki, Abdel-Hamid, Ahmed M., Fujimoto, Hajime, Hataji, Osamu, Nakahara, Hiroki, Takeshita, Atsuro, Nishihama, Kota, Okano, Tomohito, Saiki, Haruko, Okano, Yuko, Tomaru, Atsushi, Fridman D’Alessandro, Valeria, Shiraishi, Miyako, Mizoguchi, Akira, Ono, Ryoichi, Ohtsuka, Junpei, Fukumura, Masayuki, Nosaka, Tetsuya, Mi, Xuenan, Shukla, Diwakar, Kataoka, Kensuke, Kondoh, Yasuhiro, Hirose, Masaki, Arai, Toru, Inoue, Yoshikazu, Yano, Yutaka, Mackie, Roderick I., Cann, Isaac, Gabazza, Esteban C.

“…Idiopathic pulmonary fibrosis is an incurable disease of unknown etiology. Acute exacerbation of idiopathic pulmonary fibrosis is associated with high…”
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Sequence controlled secondary structure is important for the site-selectivity of lanthipeptide cyclization by Mi, Xuenan, Desormeaux, Emily K, Le, Tung T, van der Donk, Wilfred A, Shukla, Diwakar

“…Lanthipeptides are ribosomally synthesized and post-translationally modified peptides that are generated from precursor peptides through a dehydration and…”
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Long-term stimulation of angiotensin II induced endothelial senescence and dysfunction by Li, Rongxia, Mi, Xuenan, Yang, Shujun, Yang, Yunyun, Zhang, Shuyuan, Hui, Rutai, Chen, Yu, Zhang, Weili

“…The role of angiotensin II (Ang II) in hypertension has been clarified, but recent studies show that aging-associated arterial changes and those with…”
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MicroRNA-216a Promotes Endothelial Inflammation by Smad7/IκBα Pathway in Atherosclerosis by Zhang, Weili, Yang, Yunyun, Zhang, Shuyuan, Mi, Xuenan, Chen, Yu, Yang, Shujun, Hui, Rutai

“…Background. The endothelium is the first line of defence against harmful microenvironment risks, and microRNAs (miRNAs) involved in vascular inflammation may…”
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Novel Findings From a Metabolomics Study of Left Ventricular Diastolic Function: The Bogalusa Heart Study by Razavi, Alexander C, Bazzano, Lydia A, He, Jiang, Fernandez, Camilo, Whelton, Seamus P, Krousel-Wood, Marie, Li, Shengxu, Nierenberg, Jovia L, Shi, Mengyao, Li, Changwei, Mi, Xuenan, Kinchen, Jason, Kelly, Tanika N

“…Background Diastolic dysfunction is one important causal factor for heart failure with preserved ejection fraction, yet the metabolic signature associated with…”
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Novel associations between blood metabolites and kidney function among Bogalusa Heart Study and Multi-Ethnic Study of Atherosclerosis participants by Nierenberg, Jovia L., He, Jiang, Li, Changwei, Gu, Xiaoying, Shi, Mengyao, Razavi, Alexander C., Mi, Xuenan, Li, Shengxu, Bazzano, Lydia A., Anderson, Amanda H., He, Hua, Chen, Wei, Kinchen, Jason M., Rebholz, Casey M., Coresh, Josef, Levey, Andrew S., Inker, Lesley A., Shlipak, Michael, Kelly, Tanika N.

“…Introduction Chronic kidney disease (CKD) is a major public health challenge given its high global prevalence and associated risks of cardiovascular disease…”
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Functional haplotypes of the hTERT gene, leukocyte telomere length shortening, and the risk of peripheral arterial disease by Zhang, Weili, Chen, Yu, Yang, Xiaomin, Fan, Jingyao, Mi, Xuenan, Wang, Jizheng, Zhang, Channa, Hu, Frank B, Hui, Rutai

“…The development of peripheral arterial disease (PAD) is heterogeneous even in the presence of similar risk factors. Our aim was to determine whether…”
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Predicting the Activities of Drug Excipients on Biological Targets using One-Shot Learning by Mi, Xuenan, Shukla, Diwakar

“…Excipients are major components of drugs and are used to improve drug attributes such as stability and appearance. Excipients approved by the U.S. Food and…”
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3384 Serum Metabolites from the Trimethylamine Pathway Associate with Left Ventricular Diastolic Function: The Bogalusa Heart Study by Razavi, Alexander C., Fernandez, Camilo, Mi, Xuenan, He, Jiang, Bazzano, Lydia, Nierenberg, Jovia, Li, Shengxu, Kelly, Tanika N.

“…OBJECTIVES/SPECIFIC AIMS: This population-based study aims to assess the individual and collective relationship between TMA-associated metabolites and…”
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Leveraging machine learning models for peptide-protein interaction prediction by Yin, Song, Mi, Xuenan, Shukla, Diwakar

“…Peptides play a pivotal role in a wide range of biological activities through participating in up to 40% protein-protein interactions in cellular processes…”
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Leveraging machine learning models for peptideprotein interaction prediction by Yin, Song, Mi, Xuenan, Shukla, Diwakar

“…Peptides play a pivotal role in a wide range of biological activities through participating in up to 40% proteinprotein interactions in cellular processes…”
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An untargeted metabolomics study of blood pressure: findings from the Bogalusa Heart Study by He, William J., Li, Changwei, Mi, Xuenan, Shi, Mengyao, Gu, Xiaoying, Bazzano, Lydia A., Razavi, Alexander C., Nierenberg, Jovia L., Dorans, Kirsten, He, Hua, Kelly, Tanika N.

“…OBJECTIVE:To identify novel and confirm previously reported metabolites associated with SBP, DBP, and hypertension in a biracial sample of Bogalusa Heart Study…”
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Abstract P203: Serum Metabolites Associate With Blood Pressure Phenotypes in the Bogalusa Heart Study by He, William, Li, Changwei, Mi, Xuenan, Li, Shengxu, Bazzano, Lydia, Chen, Wei, He, Jiang, Kelly, Tanika

“…Abstract only We conducted a metabolome-wide association study to identify blood pressure (BP)-related metabolites among 825 white and 436 African-American…”
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Abstract 004: Novel Serum Metabolites Associate With Diastolic Function: Evidence From the Bogalusa Heart Study by Razavi, Alexander C, Fernandez, Camilo, Mi, Xuenan, He, Jiang, Bazzano, Lydia, Nierenberg, Jovia, Li, Shengxu, Kelly, Tanika N

“…Abstract only Introduction: Diastolic dysfunction is one key causal factor for heart failure with preserved ejection fraction (HFpEF). We conducted a…”
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Pseudouridine and N-formylmethionine associate with left ventricular mass index: Metabolome-wide association analysis of cardiac remodeling by Razavi, Alexander C., Bazzano, Lydia A., He, Jiang, Li, Shengxu, Fernandez, Camilo, Whelton, Seamus P., Krousel-Wood, Marie, Nierenberg, Jovia L., Shi, Mengyao, Li, Changwei, Mi, Xuenan, Kinchen, Jason, Kelly, Tanika N.

“…Heart failure (HF) is the fastest growing form of cardiovascular disease both nationally and globally, underlining a need to phenotype subclinical HF…”
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Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension by Kelly, Tanika N., Sun, Xiao, He, Karen Y., Brown, Michael R., Taliun, Sarah A. Gagliano, Hellwege, Jacklyn N., Irvin, Marguerite R., Mi, Xuenan, Brody, Jennifer A., Franceschini, Nora, Guo, Xiuqing, Hwang, Shih-Jen, de Vries, Paul S., Gao, Yan, Moscati, Arden, Nadkarni, Girish N., Yanek, Lisa R., Elfassy, Tali, Smith, Jennifer A., Chung, Ren-Hua, Beitelshees, Amber L., Patki, Amit, Aslibekyan, Stella, Blobner, Brandon M., Peralta, Juan M., Assimes, Themistocles L., Palmas, Walter R., Liu, Chunyu, Bress, Adam P., Huang, Zhijie, Hwa, Chii-Min, O’Connell, Jeffrey R., Carlson, Jenna C., Warren, Helen R., Das, Sayantan, Giri, Ayush, Martin, Lisa W., Craig Johnson, W., Fox, Ervin R., Bottinger, Erwin P., Razavi, Alexander C., Vaidya, Dhananjay, Chuang, Lee-Ming, Chang, Yen-Pei C., Jain, Deepti, Kang, Hyun Min, Hung, Adriana M., Srinivasasainagendra, Vinodh, Snively, Beverly M., Gu, Dongfeng, Montasser, May E., Reupena, Muagututi‘a Sefuiva, Heavner, Benjamin D., LeFaive, Jonathon, Hixson, James E., Rice, Kenneth M., Wang, Fei Fei, Nielsen, Jonas B., Huang, Jianfeng, Khan, Alyna T., Zhou, Wei, Nierenberg, Jovia L., Laurie, Cathy C., Armstrong, Nicole D., Shi, Mengyao, Pan, Yang, Stilp, Adrienne M., Emery, Leslie, Wong, Quenna, Minster, Ryan L., Curran, Joanne E., Munroe, Patricia B., Weeks, Daniel E., North, Kari E., Tracy, Russell P., Kenny, Eimear E., Shimbo, Daichi, Chakravarti, Aravinda, Rich, Stephen S., Blangero, John, Redline, Susan, Mitchell, Braxton D., Ida Chen, Yii-Der, Kardia, Sharon L.R., Kaplan, Robert C., Mathias, Rasika A., He, Jiang, Psaty, Bruce M., Fornage, Myriam, Loos, Ruth J.F., Correa, Adolfo, Boerwinkle, Eric, Rotter, Jerome I., Kooperberg, Charles, Edwards, Todd L., Abecasis, Gonçalo R., Zhu, Xiaofeng, Levy, Daniel, Arnett, Donna K., Morrison, Alanna C.

“…The availability of whole-genome sequencing data in large studies has enabled the assessment of coding and noncoding variants across the allele frequency…”
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Race modifies the association between animal protein metabolite 1-methylhistidine and blood pressure in middle-aged adults: the Bogalusa Heart Study by Razavi, Alexander C., Bazzano, Lydia A., He, Jiang, Whelton, Seamus P., Rebholz, Casey M., Fernandez, Camilo, Krousel-Wood, Marie, Li, Changwei, Shi, Mengyao, Nierenberg, Jovia L., Li, Shengxu, Kinchen, Jason, Mi, Xuenan, Kelly, Tanika N.

“…OBJECTIVE:Dietary factors mediate racial disparities in hypertension. However, the physiological mechanisms underlying this relationship are incompletely…”
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Abstract P1125: Serum Metabolite 1-Methylhistidine, a Marker of Red Meat and Poultry Consumption, Independently Associates With Increases in Systolic and Diastolic Blood Pressure in Middle-Aged Adults by Razavi, Alexander C, Fernandez, Camilo, Bazzano, Lydia A, He, Jiang, Krousel-Wood, Marie A, Nierenberg, Jovia, Shi, Mengyao, Li, Changwei, Mi, Xuenan, Li, Shengxu, Kinchen, Jason, Whelton, Seamus P, Kelly, Tanika N

“…Abstract only Introduction: Red meat consumption associates with heightened cardiometabolic risk. Urinary metabolite 1-methylhistidine (1-MTH) has been shown…”
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Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease by Pan, Yang, Sun, Xiao, Mi, Xuenan, Huang, Zhijie, Hsu, Yenchih, Hixson, James E, Munzy, Donna, Metcalf, Ginger, Franceschini, Nora, Tin, Adrienne, Köttgen, Anna, Francis, Michael, Brody, Jennifer A, Kestenbaum, Bryan, Sitlani, Colleen M, Mychaleckyj, Josyf C, Kramer, Holly, Lange, Leslie A, Guo, Xiuqing, Hwang, Shih-Jen, Irvin, Marguerite R, Smith, Jennifer A, Yanek, Lisa R, Vaidya, Dhananjay, Chen, Yii-Der Ida, Fornage, Myriam, Lloyd-Jones, Donald M, Hou, Lifang, Mathias, Rasika A, Mitchell, Braxton D, Peyser, Patricia A, Kardia, Sharon L R, Arnett, Donna K, Correa, Adolfo, Raffield, Laura M, Vasan, Ramachandran S, Cupple, L Adrienne, Levy, Daniel, Kaplan, Robert C, North, Kari E, Rotter, Jerome I, Kooperberg, Charles, Reiner, Alexander P, Psaty, Bruce M, Tracy, Russell P, Gibbs, Richard A, Morrison, Alanna C, Feldman, Harold, Boerwinkle, Eric, He, Jiang, Kelly, Tanika N

“…Abstract Diabetic kidney disease (DKD) is recognized as an important public health challenge. However, its genomic mechanisms are poorly understood. To…”
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