Search Results - "Mi, Sha"
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American literature news narration based on computer web technology
Published in PloS one (16-10-2023)“…Driven by internet technology, online has become the main way of news dissemination, but redundant information such as navigation bars and advertisements…”
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Quantitative investigation on the effects of ice crystal size on freeze-drying: The primary drying step
Published in Drying technology (11-01-2022)“…The size of ice crystals formed in the freezing process has a significant impact on the subsequent primary drying process. However, the effects have not been…”
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Unraveling reactive oxygen species-dependent toluene mineralization routes via construction of TixSn1−xO2 infinite solid solution photocatalysts
Published in Applied catalysis. B, Environmental (05-08-2023)“…Intermediates seriously affect the reaction process and rate in terms of kinetics. However, there are few studies on the effect of reactive oxygen species on…”
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Blocking LINGO-1 as a Therapy to Promote CNS Repair: From Concept to the Clinic
Published in CNS drugs (01-07-2013)“…LINGO-1 is a leucine-rich repeat and Ig domain-containing, Nogo receptor interacting protein, selectively expressed in the CNS on both oligodendrocytes and…”
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A review on preparing new energy ultrafine powder materials by freeze-drying
Published in Drying technology (17-08-2020)“…Efficient utilization of new energy is important way to reduce carbon emission and achieve sustainable development. High-quality new energy ultrafine powder…”
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Experimental investigation on the particle size distribution characteristics of ice slurry in double-tube heat exchanger
Published in Heat and mass transfer (01-12-2023)“…The heat transfer characteristics and particle size distribution (PSD) characteristics of ice slurry in double-tube heat exchanger (DTHE) are experimentally…”
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7
Real-time observation of the freezing stage of the mannitol solution using high-resolution optical microscopy
Published in International journal of thermal sciences (01-06-2023)“…Vacuum freeze-drying has been expanding its influence in many fields, and the freezing stage is of utmost importance for the freeze-drying process. However,…”
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8
Investigation on the thermal-fluidic characteristics of ice slurry in sinusoidal corrugated plate heat exchangers
Published in Case studies in thermal engineering (01-03-2024)“…The sinusoidal plate heat exchangers (SCPHEs) using ice slurry as coolant have a critical role for building air conditioning. However, the thermal-hydraulic…”
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9
LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway
Published in The Journal of neuroscience (22-03-2017)“…Differentiation and maturation of oligodendrocyte progenitor cells (OPCs) involve the assembly and disassembly of actin microfilaments. However, how actin…”
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LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis
Published in Nature medicine (01-10-2007)“…Demyelinating diseases, such as multiple sclerosis, are characterized by the loss of the myelin sheath around neurons, owing to inflammation and gliosis in the…”
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Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells
Published in Annals of neurology (01-03-2009)“…Objective Repair of demyelinated axons in diseases such as multiple sclerosis requires activation of the myelination program in existing or newly recruited…”
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LINGO-1 negatively regulates myelination by oligodendrocytes
Published in Nature neuroscience (01-06-2005)“…The control of myelination by oligodendrocytes in the CNS is poorly understood. Here we show that LINGO-1 is an important negative regulator of this critical…”
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13
Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis
Published in Nature (London) (17-02-2000)“…Many mammalian viruses have acquired genes from their hosts during their evolution. The rationale for these acquisitions is usually quite clear: the captured…”
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14
LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex
Published in Nature neuroscience (01-03-2004)“…Axon regeneration in the adult CNS is prevented by inhibitors in myelin. These inhibitors seem to modulate RhoA activity by binding to a receptor complex…”
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Inhibition of the Leucine-Rich Repeat Protein LINGO-1 Enhances Survival, Structure, and Function of Dopaminergic Neurons in Parkinson's Disease Models
Published in Proceedings of the National Academy of Sciences - PNAS (04-09-2007)“…The nervous system-specific leucine-rich repeat Ig-containing protein LINGO-1 is associated with the Nogo-66 receptor complex and is endowed with a canonical…”
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Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination
Published in Nature medicine (01-07-2011)“…The multiple sclerosis brain shows massive demyelination. Now, Sha Mi and colleagues show that upregulation of DR6 in multiple sclerosis brain is responsible…”
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Improving the solubility of anti‐LINGO‐1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis
Published in Protein science (01-05-2010)“…Monoclonal antibodies (Mabs) are a favorite drug platform of the biopharmaceutical industry. Currently, over 20 Mabs have been approved and several hundred…”
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NGF Regulates the Expression of Axonal LINGO-1 to Inhibit Oligodendrocyte Differentiation and Myelination
Published in The Journal of neuroscience (03-01-2007)“…Neurons and glia share a mutual dependence in establishing a functional relationship, and none is more evident than the process by which axons control…”
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TAJ/TROY, an Orphan TNF Receptor Family Member, Binds Nogo-66 Receptor 1 and Regulates Axonal Regeneration
Published in Neuron (Cambridge, Mass.) (03-02-2005)“…Myelin-associated inhibitory factors (MAIFs) are inhibitors of CNS axonal regeneration following injury. The Nogo receptor complex, composed of the Nogo-66…”
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Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site
Published in mAbs (01-01-2020)“…LINGO-1 is a membrane protein of the central nervous system (CNS) that suppresses myelination of axons. Preclinical studies have revealed that blockade of…”
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