Search Results - "Mhlanga, Musa M."

The Intersection of Epigenetics and Metabolism in Trained Immunity by Fanucchi, Stephanie, Domínguez-Andrés, Jorge, Joosten, Leo A.B., Netea, Mihai G., Mhlanga, Musa M.

“…The last few years have witnessed an increasing body of evidence that challenges the traditional view that immunological memory is an exclusive trait of the…”
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Chromosomal Contact Permits Transcription between Coregulated Genes by Fanucchi, Stephanie, Shibayama, Youtaro, Burd, Shaun, Weinberg, Marc S., Mhlanga, Musa M.

“…Transcription of coregulated genes occurs in the context of long-range chromosomal contacts that form multigene complexes. Such contacts and transcription are…”
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QuickPALM: 3D real-time photoactivation nanoscopy image processing in ImageJ by Henriques, Ricardo, Lelek, Mickael, Fornasiero, Eugenio F, Valtorta, Flavia, Zimmer, Christophe, Mhlanga, Musa M

“…correspondence: We hope that the code and suggestions provided here will inspire other researchers to take advantage of the benefits of using MLE for analyzing…”
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The lncRNA Connection Between Cellular Metabolism and Epigenetics in Trained Immunity by Fok, Ezio T, Davignon, Laurianne, Fanucchi, Stephanie, Mhlanga, Musa M

“…Trained immunity describes the ability of innate immune cells to form immunological memories of prior encounters with pathogens. Recollection of these memories…”
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PALM and STORM: Unlocking live-cell super-resolution by Henriques, Ricardo, Griffiths, Caron, Hesper Rego, E., Mhlanga, Musa M.

“…Live‐cell fluorescence light microscopy has emerged as an important tool in the study of cellular biology. The development of fluorescent markers in parallel…”
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Immune Regulation in Time and Space: The Role of Local- and Long-Range Genomic Interactions in Regulating Immune Responses by Devenish, Liam P., Mhlanga, Musa M., Negishi, Yutaka

“…Mammals face and overcome an onslaught of endogenous and exogenous challenges in order to survive. Typical immune cells and barrier cells, such as epithelia,…”
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Lnc-ing Trained Immunity to Chromatin Architecture by Fanucchi, Stephanie, Mhlanga, Musa M

“…Human innate immune cells exposed to certain infections or stimuli develop enhanced immune responses upon re-infection with a different second stimulus, a…”
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Visualization of Enhancer-Derived Noncoding RNA by Shibayama, Youtaro, Fanucchi, Stephanie, Mhlanga, Musa M

“…Enhancers are principal regulators that allow spatiotemporal tissue-specific control of gene expression. While mounting evidence suggests that enhancer-derived…”
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Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti by Scholefield, Janine, Henriques, Ricardo, Savulescu, Anca F., Fontan, Elisabeth, Boucharlat, Alix, Laplantine, Emmanuel, Smahi, Asma, Israël, Alain, Agou, Fabrice, Mhlanga, Musa

“…© The Author(s) 2016.This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this…”
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Visualizing the Distribution and Transport of mRNAs in Living Cells by Bratu, Diana P., Cha, Byeong-Jik, Mhlanga, Musa M., Kramer, Fred Russell, Tyagi, Sanjay

“…We have visualized the movements of native mRNAs in living cells. Using nuclease-resistant molecular beacons, we imaged the transport and localization of oskar…”
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Novel Inner Membrane Retention Signals in Pseudomonas aeruginosa Lipoproteins by LEWENZA, Shawn, MHLANGA, Musa M, PUGSLEY, Anthony P

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA by Barichievy, Samantha, Naidoo, Jerolen, Boullé, Mikaël, Scholefield, Janine, Parihar, Suraj P, Coussens, Anna K, Brombacher, Frank, Sigal, Alex, Mhlanga, Musa M

“…An emerging realization of infectious disease is that pathogens can cause a high incidence of genetic instability within the host as a result of…”
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Pinpointing cell identity in time and space by Savulescu, Anca F., Jacobs, Caron, Negishi, Yutaka, Davignon, Laurianne, Mhlanga, Musa

“…Copyright © 2020 Savulescu, Jacobs, Negishi, Davignon and Mhlanga. This is an open-access article distributed under the terms of the Creative Commons…”
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Genome-wide profiling of transcribed enhancers during macrophage activation by Denisenko, Elena, Guler, Reto, Mhlanga, Musa, Suzuki, Harukazu, Brombacher, Frank, Schmeier, Sebastian

“…© The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License…”
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Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses by van Deuren, Rosanne C, Arts, Peer, Cavalli, Giulio, Jaeger, Martin, Steehouwer, Marloes, van de Vorst, Maartje, Gilissen, Christian, Joosten, Leo A B, Dinarello, Charles A, Mhlanga, Musa M, Kumar, Vinod, Netea, Mihai G, van de Veerdonk, Frank L, Hoischen, Alexander

“…The interleukin (IL)-1 pathway is primarily associated with innate immunological defense and plays a major role in the induction and regulation of…”
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Quantifying spatial dynamics of Mycobacterium tuberculosis infection of human macrophages using microfabricated patterns by Savulescu, Anca F, Peton, Nashied, Oosthuizen, Delia, Hazra, Rudranil, Rousseau, Robert P, Mhlanga, Musa M, Coussens, Anna K

“…Macrophages provide a first line of defense against invading pathogens, including the leading cause of bacterial mortality, Mycobacterium tuberculosis (Mtb). A…”
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Walking the LINEs hidden in the dark matter of the genome by Lusic, Marina, Mhlanga, Musa M.

“…The function of transposable elements present in mammalian genomes remains an enigma. In this issue, Bodega, Abrignani and colleagues show that…”
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Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments by Fanucchi, Stephanie, Fok, Ezio T., Dalla, Emiliano, Shibayama, Youtaro, Börner, Kathleen, Chang, Erin Y., Stoychev, Stoyan, Imakaev, Maxim, Grimm, Dirk, Wang, Kevin C., Li, Guoliang, Sung, Wing-Kin, Mhlanga, Musa M.

“…Accumulation of trimethylation of histone H3 at lysine 4 (H3K4me3) on immune-related gene promoters underlies robust transcription during trained immunity…”
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Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation by Parihar, Suraj P., Guler, Reto, Khutlang, Rethabile, Lang, Dirk M., Hurdayal, Ramona, Mhlanga, Musa M., Suzuki, Harukazu, Marais, A. David, Brombacher, Frank

“…Background. Statins are cholesterol-lowering drugs, targeting HMG-CoA reductase, thereby reducing the risk of coronary disorders and hypercholesterolemia…”
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High-throughput SNP genotyping: combining tag SNPs and molecular beacons by Barreiro, Luis B, Henriques, Ricardo, Mhlanga, Musa M

“…In the last decade, molecular beacons have emerged to become a widely used tool in the multiplex typing of single nucleotide polymorphisms (SNPs). Improvements…”
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