Search Results - "Mezzi, Karen"

Indacaterol/glycopyrronium versus salmeterol/fluticasone in the prevention of clinically important deterioration in COPD: results from the FLAME study by Anzueto, Antonio R, Kostikas, Konstantinos, Mezzi, Karen, Shen, Steven, Larbig, Michael, Patalano, Francesco, Fogel, Robert, Banerji, Donald, Wedzicha, Jadwiga A

“…Chronic obstructive pulmonary disease (COPD) is a progressive disease and a composite endpoint could be an indicator of treatment effect on disease worsening…”
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Treatment response to indacaterol/glycopyrronium versus salmeterol/fluticasone in exacerbating COPD patients by gender: a post-hoc analysis in the FLAME study by Wedzicha, Jadwiga A, Singh, Dave, Tsiligianni, Ioanna, Jenkins, Christine, Fucile, Sebastian, Fogel, Robert, Shen, Steven, Goyal, Pankaj, Mezzi, Karen, Kostikas, Konstantinos

“…The burden of chronic obstructive lung disease (COPD) is increasing in women, with recent evidence suggesting gender differences in disease characteristics and…”
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Medication Adherence and Asthma Control with Once-Daily Indacaterol/Glycopyrronium/Mometasone Furoate Breezhaler Digital Companion: 90-Day Analysis from Germany by Woehrle, Holger, Mastoridis, Paul, Stempel, David, Kaye, Leanne, Vuong, Vy, Mezzi, Karen

“…Introduction Suboptimal adherence to inhaled asthma therapy is associated with poor clinical outcomes. Digital companion paired inhaler devices record…”
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Triple Therapy with Mometasone/Indacaterol/Glycopyrronium or Doubling the ICS/LABA Dose in GINA Step 4: IRIDIUM Analyses by van Zyl-Smit, Richard N., Kerstjens, Huib A. M., Maspero, Jorge, Tanase, Ana-Maria, Lawrence, David, Mezzi, Karen, D’Andrea, Peter, Chapman, Kenneth R.

“…Introduction GINA guidelines recommend increasing the dose of inhaled corticosteroids (ICS) as a step-up option for patients with inadequately controlled…”
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LABA/LAMA Dual Bronchodilation as a Paradigm Shift in COPD Therapy: Overview of the QVA149 IGNITE Program by Mezzi, Karen, MD, Fedele, Mark, PhD, Chen, Hungta, PhD, Banerji, Donald, MD

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Efficacy of indacaterol/glycopyrronium versus salmeterol/fluticasone in current and ex-smokers: a pooled analysis of IGNITE trials by Halpin, David M G, Vogelmeier, Claus F, Mezzi, Karen, Gupta, Pritam, Kostikas, Konstantinos, Wedzicha, Jadwiga A

“…Inhaled corticosteroids have proven to be less effective in asthmatic patients who smoke; however, there is limited information on the efficacy of inhaled…”
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Impact of the UK lockdown on people at risk of COPD by Donaldson, Gavin C., Ritchie, Andrew I., Calverley, Peter M.A., Vestbo, Jorgen, Fageras, Malin, de la Hoz, Alberto, Bucchioni, Enrica, Compton, Chris H., Mezzi, Karen, Wedzicha, Jadwiga A.

“…On 23 March 2020, the UK Government announced a nationwide lockdown in response to the COVID-19 epidemic, with people banned from leaving their homes except…”
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Once-Daily QVA149 Demonstrates Superior Outcomes in COPD Patients Previously Treated With Fixed-Dose Long-Acting β2 -Agonist/Inhaled Corticosteroid (LABA/ICS): The ILLUMINATE Study by Mezzi, Karen, MD, Pallante, John, MD, Alagappan, Vijay, MD, Chen, Hungta, PhD, Banerji, Donald, MD

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Efficacy of mometasone/indacaterol/glycopyrronium in patients with inadequately controlled asthma with respect to baseline eosinophil count: Post hoc analysis of IRIDIUM study by Kostikas, Konstantinos, Maspero, Jorge F., Chapman, Kenneth R., Mezzi, Karen, Jaumont, Xavier, Lawrence, David, van Zyl-Smit, Richard

“…Baseline characteristics could potentially guide asthma treatments. We evaluated whether baseline eosinophil levels affect the efficacy of…”
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Response to Indacaterol/Glycopyrronium (IND/GLY) by Sex in Patients with COPD: A Pooled Analysis from the IGNITE Program by Tsiligianni, Ioanna, Mezzi, Karen, Fucile, Sebastian, Kostikas, Konstantinos, Shen, Steven, Banerji, Donald, Fogel, Robert

“…In this pooled analysis, we compared the effect of indacaterol/glycopyrronium (IND/GLY) by sex versus other commonly used chronic obstructive pulmonary disease…”
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COPD clinical control as a predictor of future exacerbations: concept validation in the SPARK study population by Barrecheguren, Miriam, Kostikas, Konstantinos, Mezzi, Karen, Shen, Steven, Alcazar, Bernardino, Soler-Cataluña, Juan José, Miravitlles, Marc, Wedzicha, Jadwiga A

“…The concept of chronic obstructive pulmonary disease (COPD) control has been proposed to guide treatment decisions in COPD. In this study, we aimed to validate…”
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Osteoporosis and fracture risk associated with inhaled corticosteroid use among Swedish COPD patients: the ARCTIC study by Janson, Christer, Lisspers, Karin, Ställberg, Björn, Johansson, Gunnar, Gutzwiller, Florian S, Mezzi, Karen, Mindeholm, Linda, Bjerregaard, Bine Kjoeller, Jorgensen, Leif, Larsson, Kjell

“…The effect of inhaled corticosteroids (ICS) on the risk of osteoporosis and fracture in patients with chronic obstructive pulmonary disease (COPD) remains…”
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Structural Predictors of Lung Function Decline in Young Smokers with Normal Spirometry by Ritchie, Andrew I, Donaldson, Gavin C, Hoffman, Eric A, Allinson, James P, Bloom, Chloe I, Bolton, Charlotte E, Choudhury, Gourab, Gerard, Sarah E, Guo, Junfeng, Alves-Moreira, Luana, McGarvey, Lorcan, Sapey, Elizabeth, Stockley, Robert A, Yip, K P, Singh, Dave, Wilkinson, Tom, Fageras, Malin, Ostridge, Kristoffer, Jöns, Olaf, Bucchioni, Enrica, Compton, Chris H, Jones, Paul, Mezzi, Karen, Vestbo, Jørgen, Calverley, Peter M A, Wedzicha, Jadwiga A

“…Chronic obstructive pulmonary disease (COPD) due to tobacco smoking commonly presents when extensive lung damage has occurred. We hypothesized that structural…”
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Cost-effectiveness of the LABA/LAMA dual bronchodilator indacaterol/glycopyrronium in a Swedish healthcare setting by Price, David, Keininger, Dorothy, Costa-Scharplatz, Madlaina, Mezzi, Karen, Dimova, Maria, Asukai, Yumi, Ställberg, Björn

“…Summary Background Indacaterol/glycopyrronium (IND/GLY) is a once-daily inhaled fixed-dose combination of indacaterol (IND), a long-acting β2 -adrenergic…”
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Efficacy of once-daily, single-inhaler, fixed-dose combination of mometasone/indacaterol/glycopyrronium in patients with asthma with or without persistent airflow limitation: Post hoc analysis from the IRIDIUM study by Van Zyl-Smit, Richard N., Kerstjens, Huib AM, Maspero, Jorge F., Kostikas, Konstantinos, Hosoe, Motoi, Tanase, Ana- Maria, D'Andrea, Peter, Mezzi, Karen, Brittain, Dominic, Lawrence, David, Chapman, Kenneth R.

“…A novel, once-daily, fixed-dose combination of mometasone furoate/indacaterol acetate/glycopyrronium bromide (MF/IND/GLY) delivered via Breezhaler® is the…”
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The Impact of Exacerbation Frequency on Clinical and Economic Outcomes in Swedish COPD Patients: The ARCTIC Study by Larsson, Kjell, Janson, Christer, Lisspers, Karin, Stallberg, Bjorn, Johansson, Gunnar, Gutzwiller, Florian S, Mezzi, Karen, Bjerregaard, Bine Kjoeller, Jorgensen, Leif

“…Purpose: The aim of this study was to assess the association between exacerbation frequency and clinical and economic outcomes in patients with COPD. Patients…”
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Once-Daily QVA149 Demonstrates Superior Outcomes in COPD Patients Previously Treated With Fixed-Dose Long-Acting β 2 -Agonist/Inhaled Corticosteroid (LABA/ICS): The ILLUMINATE Study by Mezzi, Karen, Pallante, John, Alagappan, Vijay, Chen, Hungta, Banerji, Donald

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Gender differences among Swedish COPD patients: results from the ARCTIC, a real-world retrospective cohort study by Lisspers, Karin, Larsson, Kjell, Janson, Christer, Ställberg, Björn, Tsiligianni, Ioanna, Gutzwiller, Florian S., Mezzi, Karen, Bjerregaard, Bine Kjoeller, Jorgensen, Leif, Johansson, Gunnar

“…The present study aimed to generate real-world evidence regarding gender differences among chronic obstructive pulmonary disease (COPD) patients, especially as…”
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The Perception of Physicians on Gender-Specific Differences in the Diagnosis of COPD: Results from a Questionnaire-Based Survey by Raherison-Semjen, Chantal, Mezzi, Karen, Kostikas, Konstantinos, Mackay, Alexander J, Singh, Dave

“…To evaluate the perception of physicians on gender-specific differences in the diagnosis of chronic obstructive pulmonary disease (COPD) using a qualitative…”
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The effect of indacaterol/glycopyrronium versus tiotropium or salmeterol/fluticasone on the prevention of clinically important deterioration in COPD by Anzueto, Antonio R, Vogelmeier, Claus F, Kostikas, Konstantinos, Mezzi, Karen, Fucile, Sebastian, Bader, Giovanni, Shen, Steven, Banerji, Donald, Fogel, Robert

“…Endpoints that evaluate deterioration rather than improvement of disease may have clinical utility in COPD. In this analysis, we compared the effects of…”
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