Search Results - "Mezzasalma, Tara M"
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Enhancing recombinant protein quality and yield by protein stability profiling
Published in Journal of biomolecular screening (01-04-2007)“…The reliable production of large amounts of stable, high-quality proteins is a major challenge facing pharmaceutical protein biochemists, necessary for…”
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Dihydroquinone Ansamycins: Toward Resolving the Conflict between Low in Vitro Affinity and High Cellular Potency of Geldanamycin Derivatives
Published in Biochemistry (Easton) (02-05-2006)“…Heat shock protein 90 (Hsp90) is critical for the maturation of numerous client proteins, many of which are involved in cellular transformation and…”
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Thermal stability landscape for Klenow DNA polymerase as a function of pH and salt concentration
Published in Biochimica et biophysica acta (01-10-2006)“…The thermal denaturation of Klenow DNA polymerase has been characterized over a wide variety of solution conditions to obtain a relative stability landscape…”
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An Integrated Ten-Pump, Eight-Channel Parallel LC/MS System for Automated High-Throughput Analysis of Proteins
Published in Analytical chemistry (Washington) (01-12-2001)“…An integrated 10-pump eight-channel LC/MS system has been developed for automated high-throughput analysis of intact proteins in recombinant protein…”
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