Search Results - "Mezzabotta, Lavinia"
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Different Serum Free Fatty Acid Profiles in NAFLD Subjects and Healthy Controls after Oral Fat Load
Published in International journal of molecular sciences (31-03-2016)“…Free fatty acid (FFA) metabolism can impact on metabolic conditions, such as obesity and nonalcoholic fatty liver disease (NAFLD). This work studied the…”
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MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C
Published in Nature communications (15-09-2016)“…Cirrhosis likely shares common pathophysiological pathways despite arising from a variety of liver diseases. A recent GWAS identified rs641738, a polymorphism…”
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Prevention of paracentesis-induced circulatory dysfunction in cirrhosis: Standard vs half albumin doses. A prospective, randomized, unblinded pilot study
Published in Digestive and liver disease (01-11-2011)“…Highlights ► PICD is a frequent and harmful complication of large volume paracentesis in cirrhosis. ► The efficacy of albumin (8 g/L of ascites removed) in…”
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A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms
Published in Scientific reports (05-02-2019)“…Hepatocarcinogenesis is tightly linked to liver fibrosis. Recently, two GWAS variants, MICA rs2596542 and DEPDC5 rs1012068 were identified as being associated…”
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Preliminary experience with a new cytology brush in EUS-guided FNA
Published in Gastrointestinal endoscopy (01-12-2009)“…Background Despite the high diagnostic yield of EUS-guided FNA, room for technical improvements remains. Recently, the EchoBrush (Cook Endoscopy,…”
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Systemic Complications of Nonalcoholic Fatty Liver Disease: When the Liver Is Not an Innocent Bystander
Published in Seminars in liver disease (01-08-2015)“…The top three leading causes of death in patients with nonalcoholic fatty liver disease (NAFLD) in descending order are cardiovascular disease, cancer, and…”
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Clinical patterns of hepatocellular carcinoma in nonalcoholic fatty liver disease: A multicenter prospective study
Published in Hepatology (Baltimore, Md.) (01-03-2016)“…Nonalcoholic fatty liver disease (NAFLD) represents the hepatic manifestation of metabolic syndrome and may evolve into hepatocellular carcinoma (HCC). Only…”
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The combination of liver stiffness measurement and NAFLD fibrosis score improves the noninvasive diagnostic accuracy for severe liver fibrosis in patients with nonalcoholic fatty liver disease
Published in Liver international (01-05-2015)“…Background & Aims The accuracy of noninvasive tools for the diagnosis of severe fibrosis in patients with nonalcoholic fatty liver disease(NAFLD) in clinical…”
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IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis
Published in Nature genetics (01-05-2017)“…Jacob George and colleagues examine whether the association of the IFNL3 – IFNL4 region with hepatic inflammation and fibrosis is mediated by IFN-λ3 or IFN-λ4…”
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Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease
Published in Nature communications (05-03-2015)“…Tissue fibrosis is a core pathologic process that contributes to mortality in ~45% of the population and is likely to be influenced by the host genetic…”
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Peripheral insulin resistance predicts liver damage in nondiabetic subjects with nonalcoholic fatty liver disease
Published in Hepatology (Baltimore, Md.) (01-01-2016)“…Surrogate indexes of insulin resistance and insulin sensitivity are widely used in nonalcoholic fatty liver disease (NAFLD), although they have never been…”
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Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes
Published in Hepatology (Baltimore, Md.) (01-07-2016)“…A genome‐wide exome association study has identified the transmembrane 6 superfamily member 2 (TM6SF2) rs58542926 variant encoding an E167K substitution as a…”
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Serum Ferritin Levels Lack Diagnostic Accuracy for Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
Published in Clinical gastroenterology and hepatology (01-07-2014)“…Background & Aims Series studies have associated increased serum levels of ferritin with liver fibrosis in patients with nonalcoholic fatty liver disease. We…”
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Cytokeratin 18-Aspartate396 apoptotic fragment for fibrosis detection in patients with non-alcoholic fatty liver disease and chronic viral hepatitis
Published in Digestive and liver disease (01-01-2016)“…Abstract Background The combination of non-invasive markers for the detection of fibrosis in patients with chronic liver diseases is still a matter of debate…”
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Unexplained Common Bile Duct Dilatation With Normal Serum Liver Enzymes: Diagnostic Yield of Endoscopic Ultrasound and Follow-up of This Condition
Published in Journal of clinical gastroenterology (01-09-2014)“…BACKGROUND:There is scant literature about common bile duct (CBD) dilatation with normal liver function tests (LFTs). AIMS:The aims of this study were to…”
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NAFLD and Hepatocellular Carcinoma: How Big a Problem is This Really?
Published in Current hepatology reports (2014)“…A definite link between non alcoholic fatty liver disease (NAFLD) and hepatocellular carcinoma (HCC) has emerged. Diabetes, older age and the presence of…”
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Adrenal function and microbial DNA in noninfected cirrhotic patients with ascites: Relationship and effect on survival
Published in Digestive and liver disease (01-08-2015)“…Abstract Background There are few data on clinical relevance of adrenal dysfunction and its relationship with occult microbial DNA in noninfected…”
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The Natural History of Gastrointestinal Subepithelial Tumors Arising From Muscularis Propria: An Endoscopic Ultrasound Survey
Published in Journal of clinical gastroenterology (01-10-2009)“…AIMThe majority of lesions originating from muscularis propria of stomach, duodenum, and colon are gastrointestinal stromal tumors (GISTs). Surgery is…”
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Pancreatic cancer imaging: the new role of endoscopic ultrasound
Published in Journal of the Pancreas (09-01-2007)“…Pancreatic cancer is the most deadly of all gastrointestinal malignancies and has a very poor prognosis. Unfortunately, most patients present late in the…”
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