Search Results - "Mezheyeuski, A."

Emerging risk factors of recurrence and overall survival in a Swedish stage I-III colon cancer cohort by Osterman, E., Mezheyeuski, A., Sjöblom, T., Glimelius, B.

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Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features by Pellinen, Teijo, Paavolainen, Lassi, Martín-Bernabé, Alfonso, Papatella Araujo, Renata, Strell, Carina, Mezheyeuski, Artur, Backman, Max, La Fleur, Linnea, Brück, Oscar, Sjölund, Jonas, Holmberg, Erik, Välimäki, Katja, Brunnström, Hans, Botling, Johan, Moreno-Ruiz, Pablo, Kallioniemi, Olli, Micke, Patrick, Östman, Arne

“…Cancer-associated fibroblasts (CAFs) are molecularly heterogeneous mesenchymal cells that interact with malignant cells and immune cells and confer anti- and…”
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5-FU resistant colorectal cancer cells possess improved invasiveness and β III -tubulin expression by Akalovich, S, Portyanko, A, Pundik, A, Mezheyeuski, A, Doroshenko, T

“…Elevated β -tubulin levels are associated with resistance to a broad spectrum of drugs in different carcinomas and with poor prognosis of various epithelial…”
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Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function by La Fleur, Linnéa, Botling, Johan, He, Fei, Pelicano, Catarina, Zhou, Chikai, He, Chenfei, Palano, Giorgia, Mezheyeuski, Artur, Micke, Patrick, Ravetch, Jeffrey V, Karlsson, Mikael C I, Sarhan, Dhifaf

“…The progression and metastatic capacity of solid tumors are strongly influenced by immune cells in the tumor microenvironment. In non-small cell lung cancer…”
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PD-012Emerging risk factors of recurrence and overall survival in a Swedish stage I-III colon cancer cohort by Osterman, E, Mezheyeuski, A, Sjöblom, T, Glimelius, B

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Multispectral imaging for quantitative and compartment specific immune profiling of cancer tissue by Wendik, B., Backmann, M., Micke, P., Mezheyeuski, A.

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Beyond the NCCN Risk Factors in Colon Cancer: An Evaluation in a Swedish Population-Based Cohort by Osterman, Erik, Mezheyeuski, Artur, Sjöblom, Tobias, Glimelius, Bengt

“…Background The purpose of this study was to investigate whether pT3–4 and pN-subclassifications, lymph-node ratio (LNR), tumour deposits, pre- and…”
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4P Longitudinal proteogenomic profiling reveals therapeutic vulnerabilities of immunometabolism in breast cancer by Wang, K., Zerdes, I., Sifakis, E.G., Johansson, H.J., Mezheyeuski, A., Lehtiö, J., Bergh, J., Hatschek, T., Matikas, A., Foukakis, T.

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501P Spatial immunology in colorectal liver metastases by Garcia-Vicién, G., Mezheyeuski, A., Micke, P., Ruiz, N., Molleví, D.G.

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PD-0538: Rectal cancer: world-wide use of radiotherapy and the importance of more strict lymph node staging by Hammarström, K., Glimelius, B., Sjöblom, T., Mezheyeuski, A., Hult, N. Korsavidou, Imam, I., Ekström, J.

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Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ by Strell, Carina, Paulsson, Janna, Jin, Shao-Bo, Tobin, Nicholas P, Mezheyeuski, Artur, Roswall, Pernilla, Mutgan, Ceren, Mitsios, Nicholas, Johansson, Hemming, Wickberg, Sarah Marie, Svedlund, Jessica, Nilsson, Mats, Hall, Per, Mulder, Jan, Radisky, Derek C, Pietras, Kristian, Bergh, Jonas, Lendahl, Urban, Wärnberg, Fredrik, Östman, Arne

“…A better definition of biomarkers and biological processes related to local recurrence and disease progression is highly warranted for ductal breast carcinoma…”
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688PMultispectral analysis of lymphocyte complexity in periampullary adenocarcinoma by Lundgren, S, Elebro, J, Heby, M, Nodin, B, Leandersson, K, Micke, P, Jirström, K, Mezheyeuski, A

“…Abstract Background Periampullary adenocarcinomas are a heterogenous group of tumours. Tumour morphology, i.e. intestinal type (I-type) and pancreatobiliary…”
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Multispectral analysis of lymphocyte complexity in periampullary adenocarcinoma by Lundgren, S., Elebro, J., Heby, M., Nodin, B., Leandersson, K., Micke, P., Jirström, K., Mezheyeuski, A.

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688P - Multispectral analysis of lymphocyte complexity in periampullary adenocarcinoma by Lundgren, S., Elebro, J., Heby, M., Nodin, B., Leandersson, K., Micke, P., Jirström, K., Mezheyeuski, A.

“…Periampullary adenocarcinomas are a heterogenous group of tumours. Tumour morphology, i.e. intestinal type (I-type) and pancreatobiliary type (PB-type), is a…”
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570P Subclasses of microsatellite-instability colorectal cancer with unique molecular features and immune cell infiltration patterns by Wu, K., Wu, M., Luo, T., Li, F., Nunes, L., Hammarström, K., Lundin, E., Ljuslinder, I., Mezheyeuski, A., Edqvist, P-H., Löfgren-Burström, A., Zingmark, C., Edin, S., Ponten, F., Palmqvist, R., Lin, C., Glimelius, B., Sjöblom, T.

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309P Machine learning-based characterization of tumor-immune microenvironment at a spatial and multiplexed resolution in early breast cancer: A sub-study of the EORTC 10994/BIG 1-00 randomized phase III trial with long-term follow-up by Zerdes, I., Matikas, A., Mezheyeuski, A., Acs, B., Johansson, H., Manikis, G., Boyaci, C., Boman, C.E., Poncet, C., Ignatiadis, M., Bai, Y., Rimm, D., MacGrogan, G., Cameron, D.A., Bergh, J., Bonnefoi, H., Foukakis, T.

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572P Neoantigen heterogeneity among subtypes in colorectal cancer by Li, F., Luo, T., Nunes, L., Wu, M., Hammarström, K., Lundin, E., Ljuslinder, I., Mezheyeuski, A., Edqvist, P-H., Löfgren-Burström, A., Zingmark, C., Edin, S., Ponten, F., Palmqvist, R., Wu, K., Glimelius, B., Sjöblom, T., Lin, C.

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Fibroblasts in urothelial bladder cancer define stroma phenotypes that are associated with clinical outcome by Mezheyeuski, Artur, Segersten, Ulrika, Leiss, Lina Wik, Malmström, Per-Uno, Hatina, Jiri, Östman, Arne, Strell, Carina

“…Little attention was given to the interaction between tumor and stromal cells in urothelial bladder carcinoma (UBC). While recent studies point towards the…”
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A minority-group of renal cell cancer patients with high infiltration of CD20+B-cells is associated with poor prognosis by Sjöberg, Elin, Frödin, Magnus, Lövrot, John, Mezheyeuski, Artur, Johansson, Martin, Harmenberg, Ulrika, Egevad, Lars, Sandström, Per, Östman, Arne

“…Background The role of B-lymphocytes in solid tumours is unclear. Tumour biology studies have implied both anti- and pro-tumoural effects and prognostic…”
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Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation by Moreno-Ruiz, Pablo, Corvigno, Sara, te Grootenhuis, Nienke C., La Fleur, Linnéa, Backman, Max, Strell, Carina, Mezheyeuski, Artur, Hoelzlwimmer, Gabriele, Klein, Christian, Botling, Johan, Micke, Patrick, Östman, Arne

“…•High FAP stroma intensity is a poor prognosis marker in non-small cell lung cancer.•P53 mutation is positively associated with fibroblast stroma…”
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