EXPLORING THE INFLUENCE OF NEUTROPHIL-LYMPHOCYTE RATIO ON OUTCOME PREDICTION OF SEVERELY-ILL PATIENTS WITH COVID-19

EXPLORING THE INFLUENCE OF NEUTROPHIL-LYMPHOCYTE RATIO ON OUTCOME PREDICTION OF SEVERELY-ILL PATIENTS WITH COVID-19

The aim: The study conducted to have a better understanding on the role of neutrophil-lymphocyte ratio in the determination of the prognosis of COVID-19 and to assist in predicting disease severity. Materials and methods: A total of 96 patients within age group 18-80 years who were verified positive...

Full description

Saved in:
Bibliographic Details
Published in:Wiadomości lekarskie (1960) Vol. 75; no. 12; p. 2926
Main Authors: Abeid, Samir Taha, Mezedawee, Ameer Ali Suker, Alam, Yasir Salah Jumah
Format: Journal Article
Language:English
Published: Poland 2022
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
COVID-19
Humans
Lymphocytes - metabolism
Middle Aged
Neutrophils - metabolism
Prognosis
Retrospective Studies
ROC Curve
SARS-CoV-2
Young Adult
COVID-19
D-dimer
NLR
prognosis
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim: The study conducted to have a better understanding on the role of neutrophil-lymphocyte ratio in the determination of the prognosis of COVID-19 and to assist in predicting disease severity. Materials and methods: A total of 96 patients within age group 18-80 years who were verified positive for the COVID-19 by PCR, and admitted to (Al-Sader Medical City) in Al-Najaf City between (July to October 2020) were enrolled in a cohort retrospective study, Neutrophil to lymphocyte ratio was calculated via taking the absolute neutrophil count divided by the absolute lymphocyte count. Other parameters like (renal function tests, D-dimer, C-reactive protein, serum ferritin) also has been studied in relation to outcome of patients with COVID-19. Results: The Neutrophil-lymphocyte ratio was significantly associated with low oxygen saturation and poor outcome. A significant difference was found between two clusters in CRP, serum ferritin, and D-dimer level. In addition, age and obstructive airway disease were important clinical predictors for poor outcome. Conclusions: The study was a useful prognostic marker linked with poor outcome in patients admitted for COVID-19 pneumonia. Other inflammatory markers, such as ferritin, CRP, and D-dimer were also associated with critical illness and increased mortality from COVID-19 disease.
ISSN:0043-5147
DOI:10.36740/WLek202212106