Search Results - "Meyn, R."

TRIP12 as a mediator of human papillomavirus/p16-related radiation enhancement effects by Wang, L, Zhang, P, Molkentine, D P, Chen, C, Molkentine, J M, Piao, H, Raju, U, Zhang, J, Valdecanas, D R, Tailor, R C, Thames, H D, Buchholz, T A, Chen, J, Ma, L, Mason, K A, Ang, K-K, Meyn, R E, Skinner, H D

“…Patients with human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) have better responses to radiotherapy and higher overall…”
Get full text

Bcl-2 Expression Causes Redistribution of Glutathione to the Nucleus by Voehringer, D. W., McConkey, D. J., McDonnell, T. J., Brisbay, S., Meyn, R. E.

“…In this study we used HeLa cells transfected with a conditional Bcl-2 expression construct to study the effects of Bcl-2 on reduced glutathione (GSH)…”
Get full text

29 IMPACT OF EPITHELIAL-TO-MESENCHYMAL TRANSITION ON TUMOR RESPONSE TO RADIATION AND TARGETED AGENTS by Meyn, R, Ang, K.K

Get full text

Chemotherapeutic agents enhance TRAIL-induced apoptosis in prostate cancer cells by MUNSHI, A, MCDONNELL, T. J, MEYN, R. E

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) family that preferentially kills tumor cells. In…”
Get full text

Preoperative Assessment of the Pregnant Patient Undergoing Nonobstetric Surgery by Webb, Michael P., MBChB, MSc, Helander, Erik M., MBBS, Meyn, Ashley R., MD, Flynn, Trevor, BS, Urman, Richard D., MD, MBA, Kaye, Alan David, MD, PhD

“…The anesthetic management of pregnant patients can present a variety of challenges and a thorough preoperative assessment is necessary before initiating any…”
Get full text

Elevated Serum HGF Is Associated With Radioresistance and Local Recurrence in Non-Small Cell Lung Cancer by Soh, H.E, Bhardwaj, V, Cortez, M.A, Allen, P.K, Heymach, J.V, Meyn, R, Xia, D, Gomez, D.R, Skinner, H.J, Welsh, J.W

Get full text

Radiation-induced apoptosis: relevance to radiotherapy by Dewey, W C, Ling, C C, Meyn, R E

“…Radiation-induced apoptosis is reviewed in terms of: (a) the identification of apoptotic and necrotic cells, (b) observations in vitro and in vivo of…”
Get more information

Adenoviral-mediated PTEN expression radiosensitizes non-small cell lung cancer cells by suppressing DNA repair capacity by Pappas, G, Zumstein, L A, Munshi, A, Hobbs, M, Meyn, R E

“…Expression of the PTEN tumor suppressor gene is abnormal in many human cancers. Loss of PTEN expression leads to the activation of downstream signaling…”
Get full text

Vimentin (EMT Marker Protein) Score Predicts Resistance to Erlotinib and Radiation Therapy for Patients With Stage III Non-small Cell Lung Cancer on a Prospective Phase II Trial by Komaki, R.U, Kim, Y.B, Wistuba, I.I, Tang, X, Meyn, R, Allen, P.K, Wei, X, Lee, J.J, O'Reilly, M.S, Hong, W.K

Get full text

104: Vimentin (EMT Marker Protein) Score As One of Predictors Resistance to Erlotinib and Radiotherapy for Patients with Stage III Non-Small Cell Lung Cancer on A Prospective Phase II Trial by Komaki, R, Kim, Y.B, Wistuba, I, Tang, X, Meyn, R, Allen, P.K, Wei, X, Lee, I.J, O’Reilly, M.S, Blumenschein, G, Hong, W

Get full text

Redox aspects of Bcl-2 function by Voehringer, D W, Meyn, R E

“…The oncogene Bcl-2 has attracted recent research attention as recognition of the importance of Bcl-2 control over apoptosis commitment in disease development…”
Get more information

TH‐F‐105‐03: Experimental Design and Preliminary Results for High‐Resolution and High‐Throughput In‐Vitro Measurements of Proton RBE by Guan, F, Mohan, R, Dinh, J, Kerr, M, Perles, L, Mirkovic, D, Titt, U, Zhu, X, Gillin, M, Meyn, R, Lin, S, Grosshans, D

“…Purpose: To design, develop and test a novel system for rapidly acquiring large amounts of in‐vitro RBE data for protons as a function of LET, dose per…”
Get full text

mda-7 gene transfer sensitizes breast carcinoma cells to chemotherapy, biologic therapies and radiotherapy: correlation with expression of bcl-2 family members by Chada, S, Mhashilkar, A M, Liu, Y, Nishikawa, T, Bocangel, D, Zheng, M, Vorburger, S A, Pataer, A, Swisher, S G, Ramesh, R, Kawase, K, Meyn, R E, Hunt, K K

“…Current therapies used in the treatment of breast cancer are limited by systemic toxicity, rapid drug metabolism and intrinsic and acquired drug resistance. We…”
Get full text

Synergistic Inhibition of Human Lung Cancer Cell Growth by Adenovirus-mediated Wild-Type p53 Gene Transfer in Combination with Docetaxel and Radiation Therapeutics in Vitro and in Vivo by NISHIZAKI, Masahiko, MEYN, Raymond E, LEVY, Lawrence B, ATKINSON, Edward N, WHITE, R. Allen, ROTH, Jack A, LIN JI

“…Chemotherapy given sequentially or concurrently with external beam radiation therapy has emerged as a standard for the treatment of locally advanced lung…”
Get full text

Adenoviral-mediated wild-type p53 gene expression sensitizes colorectal cancer cells to ionizing radiation by SPITZ, F. R, NGUYEN, D, SKIBBER, J. M, MEYN, R. E, CRISTIANO, R. J, ROTH, J. A

“…Wild-type p53 gene transfer into the SW620 colorectal carcinoma cell line was performed using the replication-defective adenovirus Ad5/CMV/p53 to evaluate the…”
Get full text

Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols by MIRKOVIC, N, VOEHRINGER, D. W, STORY, M. D, MCCONKEY, D. J, MCDONNELL, T. J, MEYN, R. E

“…The mechanism by which Bcl-2 oncogene expression inhibits radiation-induced apoptosis has been investigated in two mouse lymphoma cell lines: line LY-as is…”
Get full text

Induction of Apoptotic Cell Death in Chronic Lymphocytic Leukemia by 2-Chloro-2′-deoxyadenosine and 9-β-D-Arabinosyl-2-fluoroadenine by Robertson, L.E., Chubb, Sherri, Meyn, Raymond E., Story, Michael, Ford, Richard, Hittelman, Walter N., Plunkett, William

“…2-Chloro-2′-deoxyadenosine (CldAdo) and 9-β-D-arabinosyl-2-fluoroadenine (F-ara-A) have shown marked activity in the treatment of indolent lymphoid…”
Get full text

Adenoviral-mediated PTEN expression radiosensitizes non-small cell lung cancer cells by suppressing DNA repair capacity by Pappas, G, Zumstein, L A, Munshi, A, Hobbs, M, Meyn, R E

Get full text

Adenovirus-mediated wild-type p53 gene expression radiosensitizes non-small cell lung cancer cells but not normal lung fibroblasts by Kawabe, A. Munshi, L. A. Zumstein, D. R. Wilson, J. A. Roth, R. E. Meyn, S.

“…Purpose : We compared the ability of adenoviral-mediated wildtype p53 RPR/INGN201(Ad5/CMV/p53) to radiosensitize nonsmall cell lung carcinoma (NSCLC) and…”
Get full text

Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo by SAEKI, Tomoyuki, MHASHILKAR, Abner, CHADA, Sunil, RAMESH, Rajagopal, SWANSON, Xin, ZOU-YANG, X. Helena, SIEGER, Kerry, KAWABE, Shinichiro, BRANCH, Cynthia D, ZUMSTEIN, Louis, MEYN, Raymond E, ROTH, Jack A

“…Overexpression of the melanoma differentiation associated gene-7 (mda-7) in vitro results in suppression of lung cancer cell proliferation. However, the…”
Get full text