Search Results - "Meyer, Ronald L."
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Axonal Protein Synthesis and Degradation Are Necessary for Efficient Growth Cone Regeneration
Published in The Journal of neuroscience (12-01-2005)“…Axonal regeneration can occur within hours of injury, the first step being the formation of a new growth cone. For sensory and retinal axons, regenerative…”
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Neuronal growth cones respond to laser-induced axonal damage
Published in Journal of the Royal Society interface (07-03-2012)“…Although it is well known that damage to neurons results in release of substances that inhibit axonal growth, release of chemical signals from damaged axons…”
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Abrogation of β-catenin signaling in oligodendrocyte precursor cells reduces glial scarring and promotes axon regeneration after CNS injury
Published in The Journal of neuroscience (30-07-2014)“…When the brain or spinal cord is injured, glial cells in the damaged area undergo complex morphological and physiological changes resulting in the formation of…”
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A photon-driven micromotor can direct nerve fibre growth
Published in Nature photonics (01-01-2012)“…Axonal path-finding is important in the development of the nervous system, nerve repair and nerve regeneration. The behaviour of the growth cone at the tip of…”
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Intraocular BDNF promotes ectopic branching, alters motility and stimulates abnormal collaterals in regenerating optic fibers
Published in Brain research (10-07-2015)“…Abstract A great deal of effort has been invested in using trophic factors and other bioactive molecules to promote cell survival and axonal regeneration in…”
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N-methyl-D-aspartate receptors strongly regulate postsynaptic activity levels during optic nerve regeneration
Published in Journal of neuroscience research (01-10-2013)“…During development, neuronal activity is used as a cue to guide synaptic rearrangements to refine connections. Many studies, especially in the visual system,…”
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Rapid Homeostatic Plasticity in the Intact Adult Visual System
Published in The Journal of neuroscience (26-09-2007)“…Neurons may possess activity-dependent homeostatic mechanisms that permit them to globally alter synaptic strength as activity varies. We used the retinotectal…”
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Growth dynamics and morphology of regenerating optic fibers in tectum are altered by injury conditions: An in vivo imaging study in goldfish
Published in Experimental neurology (01-04-2008)“…The dynamic behavior of axons in systems that normally regenerate may provide clues for promoting regeneration in humans. When the optic nerve is severed in…”
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Axonal rearrangement without reexpression of a growth associated marker: evidence from the compression of the retinotectal system in adult goldfish
Published in Restorative neurology and neuroscience (2007)“…Growing axons express a number of proteins associated with axonal growth which are thought to be critical for regeneration and sprouting. Whether these…”
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Roger Sperry and his chemoaffinity hypothesis
Published in Neuropsychologia (01-10-1998)“…In the early 1940s, Roger Sperry performed a series of insightful experiments on the visual system of lower vertebrates that led him to draw two important…”
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Large-scale synaptic errors during map formation by regenerating optic axons in the goldfish
Published in Journal of comparative neurology (1911) (28-06-1999)“…During the formation of visual maps, growing axons initially form a map by using topographically distributed cues that direct their growth and branching to the…”
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Spontaneous Retinal Activity Is Tonic and Does Not Drive Tectal Activity during Activity-Dependent Refinement in Regeneration
Published in The Journal of neuroscience (01-04-2002)“…During development, waves of activity periodically spread across retina to produce correlated activity that is thought to drive activity-dependent ordering in…”
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Tenascin-R Inhibits the Growth of Optic Fibers In Vitro But Is Rapidly Eliminated during Nerve Regeneration in the Salamander Pleurodeles waltl
Published in The Journal of neuroscience (15-01-1999)“…Tenascin-R is a multidomain molecule of the extracellular matrix in the CNS with neurite outgrowth inhibitory functions. Despite the fact that in amphibians…”
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Increased NCAM-180 Immunoreactivity and Maintenance of L1 Immunoreactivity in Injured Optic Fibers of Adult Mice
Published in Experimental neurology (01-06-2001)“…The injury related expression of two axon-growth promoting cell adhesion molecules (CAMs), NCAM-180 which is developmentally downregulated and L1 which is…”
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The growth of axons in three-dimensional astrocyte cultures
Published in Developmental biology (01-10-1989)“…The environment of the adult central nervous system (CNS) does not support axon regeneration. We have been unable to replicate this behaviour using monolayer…”
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Increased Spontaneous Unit Activity and Appearance of Spontaneous Negative Potentials in the Goldfish Tectum during Refinement of the Optic Projection
Published in The Journal of neuroscience (01-01-2000)“…Spontaneous (not retinally driven) postsynaptic activity was examined during activity-dependent refinement of optic fibers in the goldfish tectum. Unit…”
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Fine retinotopic organization of optic terminal arbors in the tectum of normal goldfish
Published in Visual neuroscience (01-09-2000)“…Although the retinotectal projection of goldfish has long been known to have a high degree of retinotopic order, the structural basis for this in terms of the…”
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Tetrodotoxin Blocks the Formation of Ocular Dominance Columns in Goldfish
Published in Science (American Association for the Advancement of Science) (05-11-1982)“…Optic fibers from both eyes were made to regenerate simultaneously into one tectum in goldfish. Autoradiography at various times later revealed that…”
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The Neurite-Promoting Effect of Laminin Is Mediated by Different Mechanisms in Embryonic and Adult Regenerating Mouse Optic Axonsin Vitro
Published in Developmental biology (01-01-1997)“…Retinal explants from embryonic or adult mice were placed on laminin or merosin substrates and the outgrowth of optic fibers was assayed under serum-free…”
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