Search Results - "Meyer, Ralf G."

Second Allograft for Hematologic Relapse of Acute Leukemia After First Allogeneic Stem-Cell Transplantation From Related and Unrelated Donors: The Role of Donor Change by CHRISTOPEIT, Maximilian, KUSS, Oliver, TISCHER, Johanna, KOLB, Hans-Jochem, UHAREK, Lutz, MEYER, Ralf G, BUNJES, Donald, SCHEID, Christof, MARTIN, Hans, NIEDERWIESER, Dietger, KRÖGER, Nicolaus, BERTZ, Hartmut, FINKE, Jürgen, SCHREZENMEIER, Hubert, SCHMID, Christoph, BACHER, Ulrike, WILHELM BEELEN, Dietrich, BORNHÄUSER, Martin, SCHWERDTFEGER, Rainer, ANDREAS BETHGE, Wolfgang, BASARA, Nadezda, GRAMATZKI, Martin

“…To evaluate the role of a second allogeneic hematopoietic stem-cell transplantation (HSCT2) given for relapsed acute leukemia (AL) after related or unrelated…”
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Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease by Cornely, Oliver A, Robertson, Michael N, Haider, Shariq, Grigg, Andrew, Geddes, Michelle, Aoun, Mickael, Heinz, Werner J, Raad, Issam, Schanz, Urs, Meyer, Ralf G, Hammond, Sarah P, Mullane, Kathleen M, Ostermann, Helmut, Ullmann, Andrew J, Zimmerli, Stefan, Van Iersel, M L P S, Hepler, Deborah A, Waskin, Hetty, Kartsonis, Nicholas A, Maertens, Johan

“…A two-part (Phase 1B/3), sequential, open-label, multicentre study evaluated the pharmacokinetics (PK) and safety of intravenous (iv) posaconazole given as…”
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Tumoral and Immunologic Response After Vaccination of Melanoma Patients With an ALVAC Virus Encoding MAGE Antigens Recognized by T Cells by VAN BAREN, Nicolas, BONNET, Marie-Claude, ESCUDIER, Bernard, NEGRIER, Sylvie, DIETRICH, Pierre-Yves, MARANINCHI, Dominique, OSANTO, Susanne, MEYER, Ralf G, RITTER, Gerd, MOINGEON, Philippe, TARTAGLIA, Jim, VAN DER BRUGGEN, Pierre, DRENO, Brigitte, COULIE, Pierre G, BOON, Thierry, KHAMMARI, Amir, DORVAL, Thierry, PIPERNO-NEUMANN, Sophie, LIENARD, Danielle, SPEISER, Daniel, MARCHAND, Marie, BRICHARD, Vincent G

“…To evaluate the toxicity, antitumoral effectiveness, and immunogenicity of repeated vaccinations with ALVAC miniMAGE-1/3, a recombinant canarypox virus…”
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Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse by Pfeiffer, Tim, Schleuning, Michael, Mayer, Jiri, Haude, Karl-Heinz, Tischer, Johanna, Buchholz, Stefanie, Bunjes, Donald, Bug, Gesine, Holler, Ernst, Meyer, Ralf G, Greinix, Hildegard, Scheid, Christof, Christopeit, Maximilian, Schnittger, Susanne, Braess, Jan, Schlimok, Günter, Spiekermann, Karsten, Ganser, Arnold, Kolb, Hans-Jochem, Schmid, Christoph

“…Based on molecular aberrations, in particular the NPM1 mutation (NPM1(mut)) and the FLT3 internal tandem duplication (Flt3-ITD), prognostic subgroups have been…”
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Varicella-zoster virus glycoproteins B and E are major targets of CD4+ and CD8+ T cells reconstituting during zoster after allogeneic transplantation by KLEEMANN, Patrick, DISTLER, Eva, TENZER, Stefan, MEYER, Ralf G, HERR, Wolfgang, WAGNER, Eva M, THOMAS, Simone, KLOBUCH, Sebastian, AUE, Steffi, SCHNURER, Elke, SCHILD, Hansjörg, THEOBALD, Matthias, PLACHTER, Bodo

“…After allogeneic hematopoietic stem-cell transplantation patients are at increased risk for herpes zoster as long as varicella-zoster virus specific T-cell…”
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Leishmaniasis, contact hypersensitivity and graft-versus-host disease: understanding the role of dendritic cell subsets in balancing skin immunity and tolerance by Kautz-Neu, Kordula, Meyer, Ralf G., Clausen, Björn E., Von Stebut, Esther

“…Please cite this paper as: Leishmaniasis, contact hypersensitivity and graft‐versus‐host disease: understanding the role of dendritic cell subsets in balancing…”
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Immunohistochemical markers for histopathological diagnosis and differentiation of acute cutaneous graft‐versus‐host disease by Wegner, Joanna, Weidenthaler‐Barth, Beate, Engelbert, Julia, Knothe, Max, Braun, Claudia, Helbig, Doris, Sacher, Christopher, Kreft, Andreas, Wagner, Eva M., Ziemer, Mirjana, Meyer, Ralf G., Stebut, Esther

“…Graft‐versus‐host disease (GvHD) is a major complication following stem‐cell or solid‐organ transplantation. Accurate diagnosis of cutaneous GvHD is…”
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Rapid molecular dissection of viral and bacterial immunomes by Sahin, Ugur, Türeci, Özlem, Graf, Claudine, Meyer, Ralf G., Lennerz, Volker, Britten, Cedrik M., Dumrese, Claudia, Scandella, Elke, Wölfel, Thomas, Ludewig, Burkhard

“…The development of preventive or therapeutic recombinant vaccines and the generation of serodiagnostic assays for infectious diseases depend essentially on the…”
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Intronic promoters and their noncoding transcripts: A new source of cancer-associated genes by Relle, Manfred, Becker, Marc, Meyer, Ralf G., Stassen, Michael, Schwarting, Andreas

“…Recent studies of mammalian genomes suggest that alternative promoters are associated with various disorders, including cancer. Here we present an intronic…”
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Rapid identification and sorting of viable virus-reactive CD4 + and CD8 + T cells based on antigen-triggered CD137 expression by Wehler, Thomas C., Karg, Michael, Distler, Eva, Konur, Abdo, Nonn, Marion, Meyer, Ralf G., Huber, Christoph, Hartwig, Udo F., Herr, Wolfgang

“…Current methods for the detection and isolation of antigen-specific CD4 + and CD8 + T cells require the availability of peptide/MHC multimers or are restricted…”
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Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease by Cornely, Oliver A, Robertson, Michael N, Haider, Shariq, Grigg, Andrew, Geddes, Michelle, Aoun, Mickael, Heinz, Werner J, Raad, Issam, Schanz, Urs, Meyer, Ralf G, Hammond, Sarah P, Mullane, Kathleen M, Ostermann, Helmut, Ullmann, Andrew J, Zimmerli, Stefan, Van Iersel, M L P S, Hepler, Deborah A, Waskin, Hetty, Kartsonis, Nicholas A, Maertens, Johan

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Addressing tumour tolerance to improve cancer immunotherapy by Meyer, Ralf G, Herr, Wolfgang

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Rituximab combined with DexaBEAM followed by high dose therapy as salvage therapy in patients with relapsed or refractory B‐cell lymphoma: mature results of a phase II multicentre study by Kirschey, Sebastian, Flohr, Thomas, Wolf, Hans H., Frickhofen, Norbert, Gramatzki, Martin, Link, Hartmut, Basara, Nadezda, Peter, Norma, Meyer, Ralf G., Schmitz, Norbert, Weidmann, Eckhart, Banat, Andre, Schulz, Andrea, Kolbe, Karin, Derigs, Guenter, Theobald, Matthias, Hess, Georg

“…Summary Salvage therapy followed by high‐dose therapy (HDT) remains a mainstay for patients with relapsed lymphoma, however no optimal regimen has been…”
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Human CD8+ memory and EBV-specific T cells show low alloreactivity in vitro and in CD34+ stem cell–engrafted NOD/SCID/IL-2Rγcnull mice by Thomas, Simone, Klobuch, Sebastian, Sommer, Maria, van Ewijk, Reyn, Theobald, Matthias, Meyer, Ralf G, Herr, Wolfgang

“…Current strategies in cellular immunotherapy of cancer and viral infections include the adoptive transfer of T cell receptor (TCR) and chimeric antigen…”
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Targeting the activation-induced antigen CD137 can selectively deplete alloreactive T cells from antileukemic and antitumor donor T-cell lines by Wehler, Thomas C., Nonn, Marion, Brandt, Britta, Britten, Cedrik M., Gröne, Mark, Todorova, Mariya, Link, Irina, Khan, Shamsul A., Meyer, Ralf G., Huber, Christoph, Hartwig, Udo F., Herr, Wolfgang

“…In HLA-incompatible hematopoietic stem cell transplantation, alloreactive donor T cells recognizing recipient mismatch HLA cause severe graft-versus-host…”
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Prophylactic transfer of CD8-depleted donor lymphocytes after T-cell–depleted reduced-intensity transplantation by Meyer, Ralf G., Britten, Cedrik M., Wehler, Daniela, Bender, Klaus, Hess, Georg, Konur, Abdo, Hartwig, Udo F., Wehler, Thomas C., Ullmann, Andrew J., Gentilini, Chiara, Uharek, Lutz, Huber, Christoph, Kolbe, Karin, Herr, Wolfgang

“…Allogeneic hematopoietic stem cell transplantation (SCT) regimens incorporating the lymphocytotoxic CD52 antibody alemtuzumab demonstrate efficient engraftment…”
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Myeloablative radioimmunotherapy in conditioning prior to haematological stem cell transplantation: closing the gap between benefit and toxicity? by Buchmann, Inga, Meyer, Ralf G., Mier, Walter, Haberkorn, Uwe

“…High-dose radio-/chemotherapy in the context of autologous and allogeneic haematopoietic stem cell transplantation is a double-edged sword. The requirement for…”
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Human epidermal Langerhans cells replenish skin xenografts and are depleted by alloreactive T cells in vivo by Hemmerling, Julia, Wegner-Kops, Joanna, von Stebut, Esther, Wolff, Diana, Wagner, Eva M, Hartwig, Udo F, André, Maya C, Theobald, Matthias, Schopf, Rudolf E, Herr, Wolfgang, Meyer, Ralf G

“…Epidermal Langerhans cells (LC) are potent APCs surveying the skin. They are crucial regulators of T cell activation in the context of inflammatory skin…”
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An open-label, prospective phase I/II study evaluating the immunogenicity and safety of a ras peptide vaccine plus GM-CSF in patients with non-small cell lung cancer by Meyer, Ralf G, Korn, Stephanie, Micke, Patrick, Becker, Kai, Huber, Christoph, Wölfel, Thomas, Buhl, Roland

“…Summary Mutations of the ras gene have been reported in 20–40% of NSCLC patients. If present, they are critical for the malignant phenotype of these tumors…”
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The use of HLA-A0201-transfected K562 as standard antigen-presenting cells for CD8 + T lymphocytes in IFN-γ ELISPOT assays by Britten, Cedrik M, Meyer, Ralf G, Kreer, Tanja, Drexler, Ingo, Wölfel, Thomas, Herr, Wolfgang

“…ELISPOT assays are increasingly used for a direct detection and quantification of single antigen-specific T cells in freshly isolated peripheral blood…”
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