Search Results - "Meyer, Hannah V"

Transcriptomic diversity in human medullary thymic epithelial cells by Carter, Jason A., Strömich, Léonie, Peacey, Matthew, Chapin, Sarah R., Velten, Lars, Steinmetz, Lars M., Brors, Benedikt, Pinto, Sheena, Meyer, Hannah V.

“…The induction of central T cell tolerance in the thymus depends on the presentation of peripheral self-epitopes by medullary thymic epithelial cells (mTECs)…”
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Unraveling the phenotypic states of human innate-like T cells: Comparative insights with conventional T cells and mouse models by Loh, Liyen, Carcy, Salomé, Krovi, Harsha S., Domenico, Joanne, Spengler, Andrea, Lin, Yong, Torres, Joshua, Prabakar, Rishvanth K., Palmer, William, Norman, Paul J., Stone, Matthew, Brunetti, Tonya, Meyer, Hannah V., Gapin, Laurent

“…The “innate-like” T cell compartment, known as Tinn, represents a diverse group of T cells that straddle the boundary between innate and adaptive immunity. We…”
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Cystatin C is associated with adverse COVID-19 outcomes in diverse populations by Kleeman, Sam O., Cordioli, Mattia, Timmers, Paul R.H. J., Khan, Atlas, Tober-Lau, Pinkus, Kurth, Florian, Demichev, Vadim, Meyer, Hannah V., Wilson, James F., Ralser, Markus, Kiryluk, Krzysztof, Ganna, Andrea, Baillie, Kenneth, Janowitz, Tobias

“…COVID-19 has highly variable clinical courses. The search for prognostic host factors for COVID-19 outcome is a priority. We performed logistic regression for…”
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Genetic and functional insights into the fractal structure of the heart by Meyer, Hannah V., Dawes, Timothy J. W., Serrani, Marta, Bai, Wenjia, Tokarczuk, Paweł, Cai, Jiashen, de Marvao, Antonio, Henry, Albert, Lumbers, R. Thomas, Gierten, Jakob, Thumberger, Thomas, Wittbrodt, Joachim, Ware, James S., Rueckert, Daniel, Matthews, Paul M., Prasad, Sanjay K., Costantino, Maria L., Cook, Stuart A., Birney, Ewan, O’Regan, Declan P.

“…The inner surfaces of the human heart are covered by a complex network of muscular strands that is thought to be a remnant of embryonic development 1 , 2 . The…”
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Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis by Beyaz, Semir, Chung, Charlie, Mou, Haiwei, Bauer-Rowe, Khristian E., Xifaras, Michael E., Ergin, Ilgin, Dohnalova, Lenka, Biton, Moshe, Shekhar, Karthik, Eskiocak, Onur, Papciak, Katherine, Ozler, Kadir, Almeqdadi, Mohammad, Yueh, Brian, Fein, Miriam, Annamalai, Damodaran, Valle-Encinas, Eider, Erdemir, Aysegul, Dogum, Karoline, Shah, Vyom, Alici-Garipcan, Aybuke, Meyer, Hannah V., Özata, Deniz M., Elinav, Eran, Kucukural, Alper, Kumar, Pawan, McAleer, Jeremy P., Fox, James G., Thaiss, Christoph A., Regev, Aviv, Roper, Jatin, Orkin, Stuart H., Yilmaz, Ömer H.

“…Little is known about how interactions of diet, intestinal stem cells (ISCs), and immune cells affect early-stage intestinal tumorigenesis. We show that a…”
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CRISPR‐induced exon skipping of β‐catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer by Mou, Haiwei, Eskiocak, Onur, Özler, Kadir A., Gorman, Megan, Yue, Junjiayu, Jin, Ying, Wang, Zhikai, Gao, Ya, Janowitz, Tobias, Meyer, Hannah V., Yu, Tianxiong, Wilkinson, John E, Kucukural, Alper, Ozata, Deniz M., Beyaz, Semir

“…CRISPR/Cas9‐driven cancer modeling studies are based on the disruption of tumor suppressor genes by small insertions or deletions (indels) that lead to…”
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CamGFR v2: A New Model for Estimating the Glomerular Filtration Rate from Standardized or Non-standardized Creatinine in Patients with Cancer by Williams, Edward H, Flint, Thomas R, Connell, Claire M, Giglio, Daniel, Lee, Hassal, Ha, Taehoon, Gablenz, Eva, Bird, Nicholas J, Weaver, James M J, Potts, Harry, Whitley, Cameron T, Bookman, Michael A, Lynch, Andy G, Meyer, Hannah V, Tavaré, Simon, Janowitz, Tobias

“…Management of patients with cancer, specifically carboplatin dosing, requires accurate knowledge of glomerular filtration rate (GFR). Direct measurement of GFR…”
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General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation by Keil, Melanie, Sonner, Jana K, Lanz, Tobias V, Oezen, Iris, Bunse, Theresa, Bittner, Stefan, Meyer, Hannah V, Meuth, Sven G, Wick, Wolfgang, Platten, Michael

“…Abstract Relapsing-remitting multiple sclerosis (MS) is characterized by phases of acute neuroinflammation followed by spontaneous remission. Termination of…”
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Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy by Kleeman, Sam O, Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef J R A, Lee, Hassal, Chantzichristos, Dimitrios, Regan, Claire, Preall, Jonathan, Sinha, Sarthak, Rosin, Nicole, Yipp, Bryan, de Almeida, Luiz G N, Biernaskie, Jeff, Dufour, Antoine, Tober-Lau, Pinkus, Ruusalepp, Arno, Bjorkegren, Johan L M, Ralser, Markus, Kurth, Florian, Demichev, Vadim, Heywood, Todd, Gao, Qing, Johannsson, Gudmundur, Koelzer, Viktor H, Walker, Brian R, Meyer, Hannah V, Janowitz, Tobias

“…Cystatin C (CyC), a secreted cysteine protease inhibitor, has unclear biological functions. Many patients exhibit elevated plasma CyC levels, particularly…”
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Genome wide association analysis of the heart using high-resolution 3D cardiac MRI identifies new genetic loci underlying cardiac structure and function by Marvao, Antonio de, Meyer, Hannah V, Dawes, Timothy J, Shi, Wenzhe, Bai, Wenjia, Rueckert, Daniel, Birney, Ewan, O'Regan, Declan P, Cook, Stuart

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Dietary suppression of MHC-II expression in intestinal epithelial cells enhances intestinal tumorigenesis by Beyaz, Semir, Chung, Charlie, Mou, Haiwei, Bauer-Rowe, Khristian E., Xifaras, Michael E., Ergin, Ilgin, Dohnalova, Lenka, Biton, Moshe, Shekhar, Karthik, Eskiocak, Onur, Papciak, Katherine, Ozler, Kadir, Almeqdadi, Mohammad, Yueh, Brian, Fein, Miriam, Annamalai, Damodaran, Valle-Encinas, Eider, Erdemir, Aysegul, Dogum, Karoline, Shah, Vyom, Alici-Garipcan, Aybuke, Meyer, Hannah V., Özata, Deniz M., Elinav, Eran, Kucukural, Alper, Kumar, Pawan, McAleer, Jeremy P., Fox, James G., Thaiss, Christoph A., Regev, Aviv, Roper, Jatin, Orkin, Stuart H., Yilmaz, Ömer H.

“…Little is known about how interactions between diet, intestinal stem cells (ISCs) and immune cells impact early stage intestinal tumorigenesis. We show that a…”
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