Search Results - "Meyer, Edwin M"

Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion by Terada, Naohiro, Hamazaki, Takashi, Oka, Masahiro, Hoki, Masanori, Mastalerz, Diana M, Nakano, Yuka, Meyer, Edwin M, Morel, Laurence, Petersen, Bryon E, Scott, Edward W

“…Recent studies have demonstrated that transplanted bone marrow cells can turn into unexpected lineages including myocytes, hepatocytes, neurons and many…”
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Multiple calcium channels and kinases mediate α7 nicotinic receptor neuroprotection in PC12 cells by Ren, Ke, Puig, Viviana, Papke, Roger L., Itoh, Yoshitsugu, Hughes, Jeffrey A., Meyer, Edwin M.

“…α7 Nicotinic receptors are calcium permeant and provide neuroprotection against many insults. We investigated the roles of intracellular calcium ions and…”
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The antinociceptive effects of α7 nicotinic agonists in an acute pain model by Damaj, M.Imad, Meyer, Edwin M, R. Martin, Billy

“…Nicotinic receptors have been found to play a role in modulating pain transmission in the CNS. Activation of cholinergic pathways by nicotine and nicotinic…”
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Dose and Promoter Effects of Adeno-Associated Viral Vector for Green Fluorescent Protein Expression in the Rat Brain by Klein, Ronald L., Hamby, Mary E., Gong, Yan, Hirko, Aaron C., Wang, Samuel, Hughes, Jeffrey A., King, Michael A., Meyer, Edwin M.

“…Previous studies demonstrated that the rat neuron-specific enolase (NSE) promoter is effective for transgene expression in the brain in a variety of…”
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Characterization of the neuroprotective and toxic effects of α7 nicotinic receptor activation in PC12 cells by Li, Yangxin, Papke, Roger L, He, Yun-Ju, Millard, William J, Meyer, Edwin M

“…The α7 nicotinic receptor partial agonist DMXB protected differentiated PC12 cells from NGF+serum deprivation over a concentration range (1–10 μM) that…”
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Alpha7 nicotinic receptor activation inhibits ethanol‐induced mitochondrial dysfunction, cytochrome c release and neurotoxicity in primary rat hippocampal neuronal cultures by Li, Yangxin, Meyer, Edwin M., Walker, Don W., Millard, William J., He, Yun‐Ju, King, Michael A.

“…Primary hippocampal neuronal cultures exhibited a concentration‐ and time‐dependent loss of cells when exposed to ethanol (EtOH). EtOH‐induced neurotoxicity…”
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Brain-derived neurotrophic factor prevents the nigrostriatal degeneration induced by human immunodeficiency virus-1 glycoprotein 120 in vivo by Nosheny, Rachel L., Ahmed, Farid, Yakovlev, Alexander, Meyer, Edwin M., Ren, Ke, Tessarollo, Lino, Mocchetti, Italo

“…Glycoprotein 120 (gp120) from the T‐tropic strain of the human immunodeficiency virus type 1 has been shown to cause neuronal apoptosis through activation of…”
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Peripheral Transgene Expression of Plasma Gelsolin Reduces Amyloid in Transgenic Mouse Models of Alzheimer's Disease by Hirko, Aaron C, Meyer, Edwin M, King, Michael A, Hughes, Jeffery A

“…The accumulation and deposition of the 40–42–amino acid peptide amyloid β (Aβ) is thought to be a critical event in the pathology of Alzheimer's disease (AD)…”
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Brain-Derived Neurotrophic Factor Prevents Human Immunodeficiency Virus Type 1 Protein gp120 Neurotoxicity in the Rat Nigrostriatal System by MOCCHETTI, ITALO, NOSHENY, RACHEL L., TANDA, GIANLUIGI, REN, KE, MEYER, EDWIN M.

“…Human immunodeficiency virus type 1 (HIV‐1) causes neuronal degeneration and, at a late stage, creates HIV‐associated dementia (HAD) and other neurological…”
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Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra by Klein, Ronald L, King, Michael A, Hamby, Mary E, Meyer, Edwin M

“…Somatic cell gene transfer was used to express a mutant form of alpha-synuclein (alpha-syn) that is associated with Parkinson's disease (PD) in the rat…”
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CD9 is associated with leukemia inhibitory factor-mediated maintenance of embryonic stem cells by Oka, Masahiro, Tagoku, Kenichi, Russell, Thomas L, Nakano, Yuka, Hamazaki, Takashi, Meyer, Edwin M, Yokota, Takashi, Terada, Naohiro

“…Mouse embryonic stem (ES) cells can proliferate indefinitely in an undifferentiated state in the presence of leukemia inhibitory factor (LIF), or differentiate…”
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Activation and inhibition of native neuronal alpha-bungarotoxin-sensitive nicotinic ACh receptors by Uteshev, Vladimir V, Meyer, Edwin M, Papke, Roger L

“…Tuberomammillary histamine neurons (TM) of the posterior hypothalamus exclusively express alpha-bungarotoxin (αBgt) sensitive nicotinic receptors, providing a…”
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Neuron-Specific Transduction in the Rat Septohippocampal or Nigrostriatal Pathway by Recombinant Adeno-associated Virus Vectors by Klein, Ronald L., Meyer, Edwin M., Peel, Alyson L., Zolotukhin, Sergei, Meyers, Craig, Muzyczka, Nicholas, King, Michael A.

“…Viral vector-mediated gene transfer in brain can provide a means for gene therapy and functional studies. However, robust and persistent transgene expression…”
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Long-Term Neuropathological and Neurochemical Effects of Nucleus Basalis Lesions in the Rat by Arendash, Gary W., Millard, William J., Dunn, Adrian J., Meyer, Edwin M.

“…The long-term effects of excitotoxic lesions in the nucleus basalis magnocellularis of the rat were found to mimic several neuropathological and chemical…”
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Rapid Neurofibrillary Tangle Formation after Localized Gene Transfer of Mutated Tau by Klein, Ronald L., Lin, Wen-Lang, Dickson, Dennis W., Lewis, Jada, Hutton, Michael, Duff, Karen, Meyer, Edwin M., King, Michael A.

“…Neurofibrillary pathology was produced in the brains of adult rats after localized gene transfer of human tau carrying the P301L mutation, which is associated…”
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Analysis of 3-(4-hydroxy, 2-Methoxybenzylidene)anabaseine selectivity and activity at human and rat alpha-7 nicotinic receptors by Meyer, E M, Kuryatov, A, Gerzanich, V, Lindstrom, J, Papke, R L

“…3-(2,4-dimethoxybenzylidene)anabaseine (GTS-21) is a selective partial agonist for rat alpha-7 nicotine receptors with reportedly much lower efficacy for human…”
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NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats by Klein, Ronald L, Hirko, Aaron C, Meyers, Craig A, Grimes, Jeremy R, Muzyczka, Nicholas, Meyer, Edwin M

“…Administration of nerve growth factor (NGF) by intracerebroventricular infusion or transplantation of NGF-secreting cells to the basal forebrain improves…”
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Medial septal/diagonal band cells express multiple functional nicotinic receptor subtypes that are correlated with firing frequency by Thinschmidt, Jeffrey S., Frazier, Charles J., King, Michael A., Meyer, Edwin M., Papke, Roger L.

“…The medial septum-diagonal band (MS/DB) contains primarily cholinergic and GABAergic neurons that project to the hippocampus, and are important for learning…”
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Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated α7 nicotinic receptor gene transfer by Thinschmidt, Jeffrey S, López-Hernández, Gretchen Y, Ren, Ke, King, Michael A, Meyer, Edwin M, Papke, Roger L

“…Abstract One approach to treatment of negative cognitive effects associated with Alzheimer's disease and schizophrenia may involve activation of neuronal α7…”
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Memory-related deficits following selective hippocampal expression of Swedish mutation amyloid precursor protein in the rat by Gong, Yan, Meyer, Edwin M., Meyers, Craig A., Klein, Ronald L., King, Michael A., Hughes, Jeffrey A.

“…The gene encoding for the Swedish double mutation (K595N/M596L) of amyloid precursor protein (APP695Swe) was expressed bilaterally in adult rat hippocampus to…”
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