Search Results - "Meyer, Brian"

Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population by Goljan, Ewa, Abouelhoda, Mohammed, ElKalioby, Mohamed M, Jabaan, Amjad, Alghithi, Nada, Meyer, Brian F, Monies, Dorota

“…It is well documented that drug responses are related to Absorption, Distribution, Metabolism, and Excretion (ADME) characteristics of individual patients…”
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Frontiers in assessing septic systems vulnerability in coastal Georgia, USA: Modeling approach and management implications by Hoghooghi, Nahal, Pippin, J Scott, Meyer, Brian K, Hodges, John B, Bledsoe, Brian P

“…Threats to public health and environmental quality from septic systems are more prevalent in areas with poorly draining soils, high water tables, or frequent…”
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Lessons Learned from Large-Scale, First-Tier Clinical Exome Sequencing in a Highly Consanguineous Population by Monies, Dorota, Abouelhoda, Mohammed, Assoum, Mirna, Moghrabi, Nabil, Rafiullah, Rafiullah, Almontashiri, Naif, Alowain, Mohammed, Alzaidan, Hamad, Alsayed, Moeen, Subhani, Shazia, Cupler, Edward, Faden, Maha, Alhashem, Amal, Qari, Alya, Aldhalaan, Hisham, Kurdi, Wesam, Khan, Sameena, Rahbeeni, Zuhair, Goljan, Ewa, Elbardisy, Hadeel, ElKalioby, Mohamed, Shah, Zeeshan, Jaafar, Amal, Albar, Ranad, Akilan, Asma, Tayeb, Hamsa, Tahir, Asma, Fawzy, Mohammed, Nasr, Mohammed, Makki, Shaza, Alfaifi, Abdullah, Akleh, Hanna, Yamani, Suad, Bubshait, Dalal, Mahnashi, Mohammed, Basha, Talal, Alsagheir, Afaf, Alsaleem, Khalid, Badawi, Manal, Bashiri, Fahad, Bohlega, Saeed, Tous, Ehab, Ahmed, Syed, Algoufi, Talal, Al-Mousa, Hamoud, Alaki, Emadia, Alhumaidi, Susan, Alghamdi, Hadeel, Alghamdi, Malak, Sahly, Ahmed, Al-Ahmari, Ali, Alkuraya, Hisham, Almehaidib, Ali, Abanemai, Mohammed, Alsohaibaini, Fahad, Arnaout, Rand, Abdel-Salam, Ghada M.H., Aldhekri, Hasan, AlKhater, Suzan, Alqadi, Khalid, Alshareef, Turki, Banjar, Hanaa, Alsahan, Nada, Abosoudah, Ibraheem, Alashwal, Abdullah, Alhajjar, Sami, Al-Mayouf, Sulaiman, Alsemari, Abdulaziz, Alshuaibi, Walaa, Altala, Saeed, Baz, Salah, Hamad, Muddathir, Abalkhail, Tariq, Alenazi, Badi, Alkaff, Alya, Almohareb, Fahad, Al Mutairi, Fuad, Alsaleh, Mona, Alzelaye, Somaya, Bahzad, Shakir, Manee, Abdulaziz Bin, Jarrad, Ola, Meriki, Neama, Albeirouti, Bassem, Alqasmi, Amal, AlBalwi, Mohammed, Makhseed, Nawal, Hassan, Saeed, Shaheen, Marwan, Sermin, Saadeh, Shahrukh, Shamsad, Hashmi, Shahrukh, Shawli, Ayman, Tamim, Abdullah, Alnahari, Ahmed, Ghemlas, Ibrahim, Hussein, Maged, Wali, Sami, Murad, Hatem, Alkuraya, Fowzan S.

“…We report the results of clinical exome sequencing (CES) on >2,200 previously unpublished Saudi families as a first-tier test. The predominance of…”
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Transcending Self Therapy: Four-Session Individual Integrative Cognitive-Behavioral Treatment: A Case Report by Polak, Kathryn, Reisweber, Jarrod, Meyer, Brian L.

“…Effective treatments for Substance Use Disorders (SUDs) are of critical importance, particularly among veterans. We present a successful application of…”
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Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development by Nahorski, Michael S, Maddirevula, Sateesh, Ishimura, Ryosuke, Alsahli, Saud, Brady, Angela F, Begemann, Anaïs, Mizushima, Tsunehiro, Guzmán-Vega, Francisco J, Obata, Miki, Ichimura, Yoshinobu, Alsaif, Hessa S, Anazi, Shams, Ibrahim, Niema, Abdulwahab, Firdous, Hashem, Mais, Monies, Dorota, Abouelhoda, Mohamed, Meyer, Brian F, Alfadhel, Majid, Eyaid, Wafa, Zweier, Markus, Steindl, Katharina, Rauch, Anita, Arold, Stefan T, Woods, C Geoffrey, Komatsu, Masaaki, Alkuraya, Fowzan S

“…Ufmylation is the post-translational modification of proteins through the addition of UFM1. Nahorksi et al. identify mutations in UFM1 and in UFC1, which…”
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An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics by Singh, Satish K, Afonina, Nataliya, Awwad, Michel, Bechtold-Peters, Karoline, Blue, Jeffrey T, Chou, Danny, Cromwell, Mary, Krause, Hans-Juergen, Mahler, Hanns-Christian, Meyer, Brian K, Narhi, Linda, Nesta, Doug P, Spitznagel, Thomas

“…Concern around the lack of monitoring of proteinaceous subvisible particulates in the 0.1-10 microm range has been heightened (Carpenter et al., 2009, J Pharm…”
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Novel Homozygous Variants of SLC13A5 Expand the Functional Heterogeneity of a Homogeneous Syndrome of Early Infantile Epileptic Encephalopathy by Alsemari, Abdulaziz, Guzmán-Vega, Francisco J, Meyer, Brian F, Arold, Stefan T

“…Early infantile epileptic encephalopathy 25 (EIEE25) is a distinct type of neonatal epileptic encephalopathy caused by autosomal recessive mutations in the…”
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Yoga for Warriors: An Intervention for Veterans With Comorbid Chronic Pain and PTSD by Chopin, Suzzette M, Sheerin, Christina M, Meyer, Brian L

“…Objective: Comorbid chronic pain and posttraumatic stress disorder (PTSD) is common in veterans; this comorbidity is associated with increased severity and…”
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Accelerating Novel Candidate Gene Discovery in Neurogenetic Disorders via Whole-Exome Sequencing of Prescreened Multiplex Consanguineous Families by Alazami, Anas M., Patel, Nisha, Shamseldin, Hanan E., Anazi, Shamsa, Al-Dosari, Mohammed S., Alzahrani, Fatema, Hijazi, Hadia, Alshammari, Muneera, Aldahmesh, Mohammed A., Salih, Mustafa A., Faqeih, Eissa, Alhashem, Amal, Bashiri, Fahad A., Al-Owain, Mohammed, Kentab, Amal Y., Sogaty, Sameera, Al Tala, Saeed, Temsah, Mohamad-Hani, Tulbah, Maha, Aljelaify, Rasha F., Alshahwan, Saad A., Seidahmed, Mohammed Zain, Alhadid, Adnan A., Aldhalaan, Hesham, AlQallaf, Fatema, Kurdi, Wesam, Alfadhel, Majid, Babay, Zainab, Alsogheer, Mohammad, Kaya, Namik, Al-Hassnan, Zuhair N., Abdel-Salam, Ghada M.H., Al-Sannaa, Nouriya, Al Mutairi, Fuad, El Khashab, Heba Y., Bohlega, Saeed, Jia, Xiaofei, Nguyen, Henry C., Hammami, Rakad, Adly, Nouran, Mohamed, Jawahir Y., Abdulwahab, Firdous, Ibrahim, Niema, Naim, Ewa A., Al-Younes, Banan, Meyer, Brian F., Hashem, Mais, Shaheen, Ranad, Xiong, Yong, Abouelhoda, Mohamed, Aldeeri, Abdulrahman A., Monies, Dorota M., Alkuraya, Fowzan S.

“…Our knowledge of disease genes in neurological disorders is incomplete. With the aim of closing this gap, we performed whole-exome sequencing on 143 multiplex…”
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Laboratory Degradation Rates of 11 Pyrethroids under Aerobic and Anaerobic Conditions by Meyer, Brian N, Lam, Chung, Moore, Sean, Jones, Russell L

“…Degradation of 11 pyrethroids was measured over approximately 100 days in three sediment/water systems under aerobic and anaerobic conditions at 25 °C in the…”
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Molecular Analysis of Congenital Hypothyroidism in Saudi Arabia: SLC26A7 Mutation Is a Novel Defect in Thyroid Dyshormonogenesis by Zou, Minjing, Alzahrani, Ali S, Al-Odaib, Ali, Alqahtani, Mohammad A, Babiker, Omer, Al-Rijjal, Roua A, BinEssa, Huda A, Kattan, Walaa E, Al-Enezi, Anwar F, Al Qarni, Ali, Al-Faham, Manar S A, Baitei, Essa Y, Alsagheir, Afaf, Meyer, Brian F, Shi, Yufei

“…Abstract Context Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder, affecting one in 3000 to 4000 newborns. Since the introduction…”
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Association of a Mutation in LACC1 With a Monogenic Form of Systemic Juvenile Idiopathic Arthritis by Wakil, Salma M., Monies, Dorota M., Abouelhoda, Mohamed, Al‐Tassan, Nada, Al‐Dusery, Haya, Naim, Ewa A., Al‐Younes, Banan, Shinwari, Jameela, Al‐Mohanna, Futwan A., Meyer, Brian F., Al‐Mayouf, Sulaiman

“…Objective The pathologic basis of systemic juvenile idiopathic arthritis (JIA) is a subject of some controversy, with evidence for both autoimmune and…”
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Clinical and genetic characteristics of 15 families with hereditary hypophosphatemia: Novel Mutations in PHEX and SLC34A3 by Acar, Sezer, BinEssa, Huda A, Demir, Korcan, Al-Rijjal, Roua A, Zou, Minjing, Çatli, Gönül, Anık, Ahmet, Al-Enezi, Anwar F, Özışık, Seçil, Al-Faham, Manar S A, Abacı, Ayhan, Dündar, Bumin, Kattan, Walaa E, Alsagob, Maysoon, Kavukçu, Salih, Tamimi, Hamdi E, Meyer, Brian F, Böber, Ece, Shi, Yufei

“…Hereditary hypophosphatemia is a group of rare renal phosphate wasting disorders. The diagnosis is based on clinical, radiological, and biochemical features,…”
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Concomitant RAS, RET/PTC, or BRAF mutations in advanced stage of papillary thyroid carcinoma by Zou, Minjing, Baitei, Essa Y, Alzahrani, Ali S, BinHumaid, Faisal S, Alkhafaji, Dania, Al-Rijjal, Roua A, Meyer, Brian F, Shi, Yufei

“…RET/PTC rearrangement, RAS, and BRAF mutations are considered to be mutually exclusive in papillary thyroid carcinoma (PTC). However, although concomitant…”
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A genome-wide association study reveals susceptibility loci for myocardial infarction/coronary artery disease in Saudi Arabs by Wakil, Salma M, Ram, Ramesh, Muiya, Nzioka P, Mehta, Munish, Andres, Editha, Mazhar, Nejat, Baz, Batoul, Hagos, Samya, Alshahid, Maie, Meyer, Brian F, Morahan, Grant, Dzimiri, Nduna

“…Abstract Background Multiple loci have been identified for coronary artery disease (CAD) by genome-wide association studies (GWAS), but no such studies on CAD…”
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Functional analysis of 22 splice-site mutations in the PHEX, the causative gene in X-linked dominant hypophosphatemic rickets by BinEssa, Huda A., Zou, Minjing, Al-Enezi, Anwar F., Alomrani, Basma, Al-Faham, Manar S.A., Al-Rijjal, Roua A., Meyer, Brian F., Shi, Yufei

“…X-linked hypophosphatemic rickets (XLH) is caused by inactivating mutations in the PHEX gene and is the most common form of hereditary rickets. The splice-site…”
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Insights of Noncanonical Splice-site Variants on RNA Splicing in Patients With Congenital Hypothyroidism by Albader, Najla, Zou, Minjing, BinEssa, Huda A, Abdi, Saba, Al-Enezi, Anwar F, Meyer, Brian F, Alzahrani, Ali S, Shi, Yufei

“…Congenital hypothyroidism (CH) is caused by mutations in the genes for thyroid hormone synthesis. In our previous investigation of CH patients, approximately…”
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Immune response and reactogenicity of intradermal administration versus subcutaneous administration of varicella-zoster virus vaccine: an exploratory, randomised, partly blinded trial by Beals, Chan R, Dr, Railkar, Radha A, PhD, Schaeffer, Andrea K, MSc, Levin, Yotam, MD, Kochba, Efrat, MD, Meyer, Brian K, PhD, Evans, Robert K, PhD, Sheldon, Eric A, MD, Lasseter, Kenneth, MD, Lang, Nancy, BSN, Weinberg, Adriana, Prof, Canniff, Jennifer, BS, Levin, Myron J, Prof

“…Summary Background The licensed live, attenuated varicella-zoster virus vaccine prevents herpes zoster in adults older than 50 years. We aimed to determine…”
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Homozygous Mutations in ADAMTS10 and ADAMTS17 Cause Lenticular Myopia, Ectopia Lentis, Glaucoma, Spherophakia, and Short Stature by Morales, Jose, Al-Sharif, Latifa, Khalil, Dania S., Shinwari, Jameela M.A., Bavi, Prashant, Al-Mahrouqi, Rahima A., Al-Rajhi, Ali, Alkuraya, Fowzan S., Meyer, Brian F., Al Tassan, Nada

“…Weill-Marchesani syndrome (WMS) is a well-characterized disorder in which patients develop eye and skeletal abnormalities. Autosomal-recessive and…”
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Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis by May-Wilson, Sebastian, Sud, Amit, Law, Philip J., Palin, Kimmo, Tuupanen, Sari, Gylfe, Alexandra, Hänninen, Ulrika A., Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Eriksson, Johan G., Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Mecklin, Jukka-Pekka, Al-Tassan, Nada A., Palles, Claire, Farrington, Susan M., Timofeeva, Maria N., Meyer, Brian F., Wakil, Salma M., Campbell, Harry, Smith, Christopher G., Idziaszczyk, Shelley, Maughan, Timothy S., Fisher, David, Kerr, Rachel, Kerr, David, Passarelli, Michael N., Figueiredo, Jane C., Buchanan, Daniel D., Win, Aung K., Hopper, John L., Jenkins, Mark A., Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steven, Conti, David, Schumacher, Fred, Casey, Graham, Aaltonen, Lauri A., Cheadle, Jeremy P., Tomlinson, Ian P., Dunlop, Malcolm G., Houlston, Richard S.

“…While dietary fat has been established as a risk factor for colorectal cancer (CRC), associations between fatty acids (FAs) and CRC have been inconsistent…”
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