Search Results - "Mews, Makaela"
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LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans
Published in Genetics (Austin) (01-08-2017)“…An extended meiotic prophase is a hallmark of oogenesis. Hormonal signaling activates the CDK1/cyclin B kinase to promote oocyte meiotic maturation, which…”
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Leveraging the use of meta‐analysis summary statistics to improve gene expression prediction models
Published in Alzheimer's & dementia (01-12-2022)“…Background Genetically regulated gene expression as assessed via Transcriptome‐wide association studies (TWAS) can be used to elucidate the mechanistic basis…”
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Improving gene expression prediction models through the use of meta‐analysis summary statistics
Published in Alzheimer's & dementia (01-12-2023)“…Background By focusing on a gene‐level rather than a single‐variant basis, transcriptome‐wide association studies (TWAS) assess the role of genetically…”
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Journal Article