Search Results - "Meurs, Joyce van"

Gut microbiome-wide association study of depressive symptoms by Radjabzadeh, Djawad, Bosch, Jos A., Uitterlinden, André G., Zwinderman, Aeilko H., Ikram, M. Arfan, van Meurs, Joyce B. J., Luik, Annemarie I., Nieuwdorp, Max, Lok, Anja, van Duijn, Cornelia M., Kraaij, Robert, Amin, Najaf

“…Depression is one of the most poorly understood diseases due to its elusive pathogenesis. There is an urgency to identify molecular and biological mechanisms…”
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Intestinal microbiome composition and its relation to joint pain and inflammation by Boer, Cindy G., Radjabzadeh, Djawad, Medina-Gomez, Carolina, Garmaeva, Sanzhima, Schiphof, Dieuwke, Arp, Pascal, Koet, Thomas, Kurilshikov, Alexander, Fu, Jingyuan, Ikram, M. Arfan, Bierma-Zeinstra, Sita, Uitterlinden, André G., Kraaij, Robert, Zhernakova, Alexandra, van Meurs, Joyce B. J.

“…Macrophage-mediated inflammation is thought to have a causal role in osteoarthritis-related pain and severity, and has been suggested to be triggered by…”
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Diversity, compositional and functional differences between gut microbiota of children and adults by Radjabzadeh, Djawad, Boer, Cindy G., Beth, Sanne A., van der Wal, Pelle, Kiefte-De Jong, Jessica C., Jansen, Michelle A. E., Konstantinov, Sergey R., Peppelenbosch, Maikel P., Hays, John P., Jaddoe, Vincent W. V., Ikram, M. Arfan, Rivadeneira, Fernando, van Meurs, Joyce B. J., Uitterlinden, André G., Medina-Gomez, Carolina, Moll, Henriette A., Kraaij, Robert

“…The gut microbiota has been shown to play diverse roles in human health and disease although the underlying mechanisms have not yet been fully elucidated…”
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Cam Deformity and Acetabular Dysplasia as Risk Factors for Hip Osteoarthritis by Saberi Hosnijeh, Fatemeh, Zuiderwijk, Maria E., Versteeg, Mathijs, Smeele, Hieronymus T. W., Hofman, Albert, Uitterlinden, André G., Agricola, Rintje, Oei, Edwin H. G., Waarsing, Jan H., Bierma‐Zeinstra, Sita M., van Meurs, Joyce B. J.

“…Objective Cam deformity and acetabular dysplasia have been recognized as relevant risk factors for hip osteoarthritis (OA) in a few prospective studies with…”
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Multimodal Machine Learning-based Knee Osteoarthritis Progression Prediction from Plain Radiographs and Clinical Data by Tiulpin, Aleksei, Klein, Stefan, Bierma-Zeinstra, Sita M. A., Thevenot, Jérôme, Rahtu, Esa, Meurs, Joyce van, Oei, Edwin H. G., Saarakkala, Simo

“…Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction…”
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Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis by Zengini, Eleni, Hatzikotoulas, Konstantinos, Tachmazidou, Ioanna, Steinberg, Julia, Hartwig, Fernando P., Southam, Lorraine, Hackinger, Sophie, Boer, Cindy G., Styrkarsdottir, Unnur, Gilly, Arthur, Suveges, Daniel, Killian, Britt, Ingvarsson, Thorvaldur, Jonsson, Helgi, Babis, George C., McCaskie, Andrew, Uitterlinden, Andre G., van Meurs, Joyce B. J., Thorsteinsdottir, Unnur, Stefansson, Kari, Davey Smith, George, Wilkinson, Jeremy M., Zeggini, Eleftheria

“…Osteoarthritis is a common complex disease imposing a large public-health burden. Here, we performed a genome-wide association study for osteoarthritis, using…”
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High Bone Mineral Density and Fracture Risk in Type 2 Diabetes as Skeletal Complications of Inadequate Glucose Control: The Rotterdam Study by OEI, Ling, ZILLIKENS, M. Carola, HOFMAN, Albert, VAN LEEUWEN, Johannes P. T. M, WITTEMAN, Jacqueline C. M, POLS, Huibert A. P, UITTERLINDEN, André G, KLAVER, Caroline C. W, FRANCO, Oscar H, RIVADENEIRA, Fernando, DEHGHAN, Abbas, BUITENDIJK, GabriËlle H. S, CASTANO-BETANCOURT, Martha C, ESTRADA, Karol, STOLK, Lisette, OEI, Edwin H. G, VAN MEURS, Joyce B. J, JANSSEN, Joseph A. M. J. L

“…Individuals with type 2 diabetes have increased fracture risk despite higher bone mineral density (BMD). Our aim was to examine the influence of glucose…”
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The Association Between Lumbar Disc Degeneration and Low Back Pain: The Influence of Age, Gender, and Individual Radiographic Features by DE SCHEPPER, Evelien I. T, DAMEN, Jurgen, VAN MEURS, Joyce B. J, GINAI, Abida Z, POPHAM, Maria, HOFMAN, Albert, KOES, Bart W, BIERMA-ZEINSTRA, Sita M

“…Cross-sectional open population based study (nested in a prospective cohort study). To explore the association of the different individual radiographic…”
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Mild hyponatremia as a risk factor for fractures: The rotterdam study by Hoorn, Ewout J, Rivadeneira, Fernando, van Meurs, Joyce BJ, Ziere, Gijsbertus, Stricker, Bruno HCh, Hofman, Albert, Pols, Huibert AP, Zietse, Robert, Uitterlinden, André G, Zillikens, M Carola

“…Recent studies suggest that mild hyponatremia is associated with fractures, but prospective studies are lacking. We studied whether hyponatremia is associated…”
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Large-Scale Analysis of Association Between LRP5 and LRP6 Variants and Osteoporosis by van Meurs, Joyce B. J, Trikalinos, Thomas A, Ralston, Stuart H, Balcells, Susana, Brandi, Maria Luisa, Brixen, Kim, Kiel, Douglas P, Langdahl, Bente L, Lips, Paul, Ljunggren, Östen, Lorenc, Roman, Obermayer-Pietsch, Barbara, Ohlsson, Claes, Pettersson, Ulrika, Reid, David M, Rousseau, Francois, Scollen, Serena, Van Hul, Wim, Agueda, Lidia, Åkesson, Kristina, Benevolenskaya, Lidia I, Ferrari, Serge L, Hallmans, Göran, Hofman, Albert, Husted, Lise Bjerre, Kruk, Marcin, Kaptoge, Stephen, Karasik, David, Karlsson, Magnus K, Lorentzon, Mattias, Masi, Laura, McGuigan, Fiona E. A, Mellström, Dan, Mosekilde, Leif, Nogues, Xavier, Pols, Huibert A. P, Reeve, Jonathan, Renner, Wilfried, Rivadeneira, Fernando, van Schoor, Natasja M, Weber, Kurt, Ioannidis, John P. A, Uitterlinden, André G, GENOMOS Study, for the

“…CONTEXT Mutations in the low-density lipoprotein receptor–related protein 5 (LRP5) gene cause rare syndromes characterized by altered bone mineral density…”
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Association between biomarkers of tissue inflammation and progression of osteoarthritis: evidence from the Rotterdam study cohort by Saberi Hosnijeh, Fatemeh, Siebuhr, Anne Sofie, Uitterlinden, Andre G, Oei, Edwin H G, Hofman, Albert, Karsdal, Morten A, Bierma-Zeinstra, Sita M, Bay-Jensen, Anne C, van Meurs, Joyce B J

“…We aimed to investigate the prognostic value of two biomarkers of tissue inflammation, matrix metalloproteinase-dependent degradation of C-reactive protein…”
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Role of Epigenomics in Bone and Cartilage Disease by van Meurs, Joyce BJ, Boer, Cindy G, Lopez‐Delgado, Laura, Riancho, Jose A

“…ABSTRACT Phenotypic variation in skeletal traits and diseases is the product of genetic and environmental factors. Epigenetic mechanisms include…”
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Epigenome-wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis by Nano, Jana, Ghanbari, Mohsen, Wang, Wenshi, de Vries, Paul S, Dhana, Klodian, Muka, Taulant, Uitterlinden, André G, van Meurs, Joyce B.J, Hofman, Albert, Franco, Oscar H, Pan, Qiuwei, Darwish Murad, Sarwa, Dehghan, Abbas

“…Abstract Background & aims Epigenetic mechanisms might be involved in the regulation of liver enzyme level. We aimed to identify CpG sites at which DNA…”
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An Epigenome-Wide Association Study of Obesity-Related Traits by Dhana, Klodian, Braun, Kim V E, Nano, Jana, Voortman, Trudy, Demerath, Ellen W, Guan, Weihua, Fornage, Myriam, van Meurs, Joyce B J, Uitterlinden, Andre G, Hofman, Albert, Franco, Oscar H, Dehghan, Abbas

“…Abstract We conducted an epigenome-wide association study on obesity-related traits. We used data from 2 prospective, population-based cohort studies: the…”
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Disease variants alter transcription factor levels and methylation of their binding sites by Bonder, Marc Jan, Luijk, René, Zhernakova, Daria V, Moed, Matthijs, Deelen, Patrick, Vermaat, Martijn, van Iterson, Maarten, van Dijk, Freerk, van Galen, Michiel, Bot, Jan, Slieker, Roderick C, Jhamai, P Mila, Verbiest, Michael, Suchiman, H Eka D, Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Arindrarto, Wibowo, Kielbasa, Szymon M, Jonkers, Iris, van 't Hof, Peter, Nooren, Irene, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Zhernakova, Alexandra, Tigchelaar, Ettje F, Swertz, Morris A, Hofman, Albert, Uitterlinden, André G, Pool, René, van Dongen, Jenny, Hottenga, Jouke J, Stehouwer, Coen D A, van der Kallen, Carla J H, Schalkwijk, Casper G, van den Berg, Leonard H, van Zwet, Erik W, Mei, Hailiang, Li, Yang, Lemire, Mathieu, Hudson, Thomas J, Slagboom, P Eline, Wijmenga, Cisca, Veldink, Jan H, van Greevenbroek, Marleen M J, van Duijn, Cornelia M, Boomsma, Dorret I, Isaacs, Aaron, Jansen, Rick, van Meurs, Joyce B J, 't Hoen, Peter A C, Franke, Lude, Heijmans, Bastiaan T

“…Peter 't Hoen, Lude Franke, Bastiaan Heijmans and colleagues present a combined analysis of methylome and transcriptome data from a large collection of…”
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Epigenetic Link Between Statin Therapy and Type 2 Diabetes by Ochoa-Rosales, Carolina, Portilla-Fernandez, Eliana, Nano, Jana, Wilson, Rory, Lehne, Benjamin, Mishra, Pashupati P, Gao, Xu, Ghanbari, Mohsen, Rueda-Ochoa, Oscar L, Juvinao-Quintero, Diana, Loh, Marie, Zhang, Weihua, Kooner, Jaspal S, Grabe, Hans J, Felix, Stephan B, Schöttker, Ben, Zhang, Yan, Gieger, Christian, Müller-Nurasyid, Martina, Heier, Margit, Peters, Annette, Lehtimäki, Terho, Teumer, Alexander, Brenner, Hermann, Waldenberger, Melanie, Ikram, M Arfan, van Meurs, Joyce B J, Franco, Oscar H, Voortman, Trudy, Chambers, John, Stricker, Bruno H, Muka, Taulant

“…To investigate the role of epigenetics in statins' diabetogenic effect comparing DNA methylation (DNAm) between statin users and nonusers in an epigenome-wide…”
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Identification of context-dependent expression quantitative trait loci in whole blood by Zhernakova, Daria V, Deelen, Patrick, Vermaat, Martijn, van Iterson, Maarten, van Galen, Michiel, Arindrarto, Wibowo, van 't Hof, Peter, Mei, Hailiang, van Dijk, Freerk, Westra, Harm-Jan, Bonder, Marc Jan, van Rooij, Jeroen, Verkerk, Marijn, Jhamai, P Mila, Moed, Matthijs, Kielbasa, Szymon M, Bot, Jan, Nooren, Irene, Pool, René, van Dongen, Jenny, Hottenga, Jouke J, Stehouwer, Coen D A, van der Kallen, Carla J H, Schalkwijk, Casper G, Zhernakova, Alexandra, Li, Yang, Tigchelaar, Ettje F, de Klein, Niek, Beekman, Marian, Deelen, Joris, van Heemst, Diana, van den Berg, Leonard H, Hofman, Albert, Uitterlinden, André G, van Greevenbroek, Marleen M J, Veldink, Jan H, Boomsma, Dorret I, van Duijn, Cornelia M, Wijmenga, Cisca, Slagboom, P Eline, Swertz, Morris A, Isaacs, Aaron, van Meurs, Joyce B J, Jansen, Rick, Heijmans, Bastiaan T, 't Hoen, Peter A C, Franke, Lude

“…Bastiaan Heijmans, Peter ’t Hoen, Lude Franke and colleagues describe a strategy to identify context-dependent expression quantitative trait loci (eQTLs). They…”
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A comparison of genotyping arrays by Verlouw, Joost A M, Clemens, Eva, de Vries, Jard H, Zolk, Oliver, Verkerk, Annemieke J M H, Am Zehnhoff-Dinnesen, Antoinette, Medina-Gomez, Carolina, Lanvers-Kaminsky, Claudia, Rivadeneira, Fernando, Langer, Thorsten, van Meurs, Joyce B J, van den Heuvel-Eibrink, Marry M, Uitterlinden, André G, Broer, Linda

“…Array technology to genotype single-nucleotide variants (SNVs) is widely used in genome-wide association studies (GWAS), clinical diagnostics, and linkage…”
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Plasma proteomics identifies CRTAC1 as a biomarker for osteoarthritis severity and progression by Szilagyi, Ingrid A, Vallerga, Costanza L, Boer, Cindy G, Schiphof, Dieuwke, Ikram, M Arfan, Bierma-Zeinstra, Sita M A, van Meurs, Joyce B J

“…Abstract Objectives The aim of this study was to identify biomarkers for radiographic OA severity and progression acting within the inflammation and metabolic…”
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Advanced Glycation End Products (AGEs) in Diet and Skin in Relation to Stool Microbiota: The Rotterdam Study by Chen, Jinluan, Radjabzadeh, Djawad, Medina-Gomez, Carolina, Voortman, Trudy, van Meurs, Joyce B J, Ikram, M Arfan, Uitterlinden, André G, Kraaij, Robert, Zillikens, M Carola

“…Advanced glycation end products (AGEs) are involved in age-related diseases, but the interaction of gut microbiota with dietary AGEs (dAGEs) and tissue AGEs in…”
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