Search Results - "Meurs, Illiana"

Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies by Geerling, Janine J., Boon, Mariëtte R., Kooijman, Sander, Parlevliet, Edwin T., Havekes, Louis M., Romijn, Johannes A., Meurs, Illiana M., Rensen, Patrick C.N.

“…Important players in triglyceride (TG) metabolism include the liver (production), white adipose tissue (WAT) (storage), heart and skeletal muscle (combustion…”
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Genetic Variant of the Scavenger Receptor BI in Humans by Vergeer, Menno, Korporaal, Suzanne J.A, Franssen, Remco, Meurs, Illiana, Out, Ruud, Hovingh, G. Kees, Hoekstra, Menno, Sierts, Jeroen A, Dallinga-Thie, Geesje M, Motazacker, Mohammad Mahdi, Holleboom, Adriaan G, Van Berkel, Theo J.C, Kastelein, John J.P, Van Eck, Miranda, Kuivenhoven, Jan Albert

“…In a family with high HDL, a genetic mutation was identified. In addition to higher HDL levels, carriers had reduced cholesterol efflux from macrophages,…”
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Combined Deletion of Macrophage ABCA1 and ABCG1 Leads to Massive Lipid Accumulation in Tissue Macrophages and Distinct Atherosclerosis at Relatively Low Plasma Cholesterol Levels by Out, Ruud, Hoekstra, Menno, Habets, Kim, Meurs, Illiana, de Waard, Vivian, Hildebrand, Reeni B, Wang, Yanan, Chimini, Giovanna, Kuiper, Johan, Van Berkel, Theo J.C, Van Eck, Miranda

“…OBJECTIVE—The purpose of this study was to evaluate the effect of the combined deletion of ABCA1 and ABCG1 expression in macrophages on foam cell formation and…”
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ATP-binding cassette transporters A1 and G1, HDL metabolism, cholesterol efflux, and inflammation: important targets for the treatment of atherosclerosis by Ye, Dan, Lammers, Bart, Zhao, Ying, Meurs, Illiana, Van Berkel, T J, Van Eck, Miranda

“…Atherosclerosis has been characterized as a chronic inflammatory response to cholesterol deposition in arteries. Plasma high density lipoprotein (HDL) levels…”
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The effect of ABCG1 deficiency on atherosclerotic lesion development in LDL receptor knockout mice depends on the stage of atherogenesis by Meurs, Illiana, Lammers, Bart, Zhao, Ying, Out, Ruud, Hildebrand, Reeni B, Hoekstra, Menno, Van Berkel, Theo J.C, Van Eck, Miranda

“…Abstract Objective As ABCG1 plays a role in cholesterol efflux, macrophage ABCG1 expression has been suggested to protect against atherosclerosis. However, we…”
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Macrophage ABCG1 Deletion Disrupts Lipid Homeostasis in Alveolar Macrophages and Moderately Influences Atherosclerotic Lesion Development in LDL Receptor-Deficient Mice by Out, Ruud, Hoekstra, Menno, Hildebrand, Reeni B, Kruit, Janine K, Meurs, Illiana, Li, Zhaosha, Kuipers, Folkert, Van Berkel, Theo J.C, Van Eck, Miranda

“…OBJECTIVE—ABCG1 has recently been identified as a facilitator of cellular cholesterol and phospholipid efflux to high-density lipoprotein (HDL). Its expression…”
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Inhibition of the central melanocortin system decreases brown adipose tissue activity[S] by Kooijman, Sander, Boon, Mariëtte R., Parlevliet, Edwin T., Geerling, Janine J., van de Pol, Vera, Romijn, Johannes A., Havekes, Louis M., Meurs, Illiana, Rensen, Patrick C.N.

“…The melanocortin system is an important regulator of energy balance, and melanocortin 4 receptor (MC4R) deficiency is the most common monogenic cause of…”
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Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development by Pennings, Marieke, Meurs, Illiana, Ye, Dan, Out, Ruud, Hoekstra, Menno, Van Berkel, Theo J.C., Eck, Miranda Van

“…Foam cell formation due to excessive accumulation of cholesterol by macrophages is a pathological hallmark of atherosclerosis. Macrophages cannot limit the…”
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Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting by Hoekstra, Menno, Meurs, Illiana, Koenders, Mieke, Out, Ruud, Hildebrand, Reeni B., Kruijt, J. Kar, Van Eck, Miranda, Van Berkel, Theo J.C.

“…Receptor-mediated cholesterol uptake has been suggested to play a role in maintaining the adrenal intracellular free cholesterol pool and the ability to…”
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High-density lipoprotein: key molecule in cholesterol efflux and the prevention of atherosclerosis by Meurs, Illiana, Van Eck, Miranda, Van Berkel, Theo J C

“…Accumulation of cholesterol by macrophages, leading to their transformation into foam cells is a key event in the initiation of atherosclerosis. As maintenance…”
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Total Body ABCG1 Expression Protects Against Early Atherosclerotic Lesion Development in Mice by Out, Ruud, Hoekstra, Menno, Meurs, Illiana, de Vos, Paula, Kuiper, Johan, Van Eck, Miranda, Van Berkel, Theo J.C

“…OBJECTIVE—ABCG1 has recently been identified as a facilitator of cholesterol and phospholipid efflux from macrophages to HDL. In bone marrow transplantation…”
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Macrophage Adipose Triglyceride Lipase Deficiency Attenuates Atherosclerotic Lesion Development in Low-Density Lipoprotein Receptor Knockout Mice by Lammers, Bart, Chandak, Prakash G, Aflaki, Elma, Van Puijvelde, Gijs H.M, Radovic, Branislav, Hildebrand, Reeni B, Meurs, Illiana, Out, Ruud, Kuiper, Johan, Van Berkel, Theo J.C, Kolb, Dagmar, Haemmerle, Guenter, Zechner, Rudolf, Levak-Frank, Sanja, Van Eck, Miranda, Kratky, Dagmar

“…OBJECTIVE—The consequences of macrophage triglyceride (TG) accumulation on atherosclerosis have not been studied in detail so far. Adipose triglyceride lipase…”
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Augmented atherogenesis in LDL receptor deficient mice lacking both macrophage ABCA1 and ApoE by Lammers, Bart, Zhao, Ying, Hoekstra, Menno, Hildebrand, Reeni B, Ye, Dan, Meurs, Illiana, Van Berkel, Theo J C, Van Eck, Miranda

“…ABCA1 protects against atherosclerosis by facilitating cholesterol efflux from macrophage foam cells in the arterial wall to extracellular apolipoprotein (apo)…”
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Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1 by Meurs, Illiana, Calpe-Berdiel, Laura, Habets, Kim L L, Zhao, Ying, Korporaal, Suzanne J A, Mommaas, A Mieke, Josselin, Emmanuelle, Hildebrand, Reeni B, Ye, Dan, Out, Ruud, Kuiper, Johan, Van Berkel, Theo J C, Chimini, Giovanna, Van Eck, Miranda

“…ABCA7, a close relative of ABCA1 which facilitates cholesterol efflux to lipid-poor apoproteins, has been implicated in macrophage lipid efflux and clearance…”
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Correction: Effects of Deletion of Macrophage ABCA7 on Lipid Metabolism and the Development of Atherosclerosis in the Presence and Absence of ABCA1 by Meurs, Illiana, Calpe-Berdiel, Laura, Habets, Kim L. L., Zhao, Ying, Korporaal, Suzanne J. A., Mommaas, A. Mieke, Josselin, Emmanuelle, Hildebrand, Reeni B., Ye, Dan, Out, Ruud, Kuiper, Johan, Van Berkel, Theo J. C., Chimini, Giovanna, Van Eck, Miranda

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Hepatic cell-specific ATP-binding cassette (ABC) transporter profiling identifies putative novel candidates for lipid homeostasis in mice by Ye, Dan, Hoekstra, Menno, Out, Ruud, Meurs, Illiana, Kruijt, J. Kar, Hildebrand, Reeni B, Van Berkel, Theo J.C, Van Eck, Miranda

“…Abstract Background ABC-transporters play an important role in lipid trafficking. Therefore, hepatic expression patterns of ABC-transporters involved in the…”
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The European Medicines Agency's approval of proprotein convertase subtilisin/kexin type 9 inhibitors by Blind, Eberhard, de Graeff, Pieter A, Meurs, Illiana, Holtkamp, Frank, Baczynska, Ania, Janssen, Heidi

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Splenic autonomic denervation increases inflammatory status but does not aggravate atherosclerotic lesion development by Kooijman, Sander, Meurs, Illiana, van Beek, Lianne, Khedoe, P Padmini S J, Giezekamp, Annabel, Pike-Overzet, Karin, Cailotto, Cathy, van der Vliet, Jan, van Harmelen, Vanessa, Boeckxstaens, Guy, Berbée, Jimmy F P, Rensen, Patrick C N

“…The brain plays a prominent role in the regulation of inflammation. Immune cells are under control of the so-called cholinergic anti-inflammatory reflex,…”
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Deletion of the High-Density Lipoprotein Receptor Scavenger Receptor BI in Mice Modulates Thrombosis Susceptibility and Indirectly Affects Platelet Function by Elevation of Plasma Free Cholesterol by Korporaal, Suzanne J.A, Meurs, Illiana, Hauer, Arnaud D, Hildebrand, Reeni B, Hoekstra, Menno, Ten Cate, Hugo, Praticò, Domenico, Akkerman, Jan-Willem N, Van Berkel, Theo J.C, Kuiper, Johan, Van Eck, Miranda

“…OBJECTIVE—Scavenger receptor BI (SR-BI) is a cell surface receptor that promotes the selective uptake of cholesteryl esters from high-density lipoprotein (HDL)…”
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Abstract 202: Inhibition of Central Melanocortin 4 Receptor Signaling Severely Impairs Brown Adipose Tissue Activity and VLDL Metabolism by Berbée, Jimmy F, Kooijman, Sander, Boon, Mariëtte R, Parlevliet, Edwin T, Geerling, Janine J, Havekes, Louis M, Meurs, Illiana, Rensen, Patrick C

“…Abstract only Objectives: SNPs near the melanocortin 4 receptor (MC4R) gene are associated with cardiovascular diseases (CVD) and deficiency of MC4R is the…”
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