Search Results - "Meurer, Roger D."

Spiroimidazolidinone NPC1L1 inhibitors. Part 2: Structure–activity studies and in vivo efficacy by Howell, Kobporn L., DeVita, Robert J., Garcia-Calvo, Margarita, Meurer, Roger D., Lisnock, JeanMarie, Bull, Herbert G., McMasters, Daniel R., McCann, Margaret E., Mills, Sander G.

“…Ezetimibe (Zetia®), a cholesterol-absorption inhibitor (CAI) approved by the FDA for the treatment of hypercholesterolemia, is believed to target the intestine…”
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Reconstituted HDL elicits marked changes in plasma lipids following single-dose injection in C57Bl/6 mice by Chen, Zhu, O'Neill, Edward A, Meurer, Roger D, Gagen, Karen, Luell, Silvi, Wang, Sheng-Ping, Ichetovkin, Marina, Frantz-Wattley, Betsy, Eveland, Suzanne, Strack, Alison M, Fisher, Timothy S, Johns, Douglas G, Sparrow, Carl P, Wright, Samuel D, Hubbard, Brian K, Carballo-Jane, Ester

“…High-density lipoprotein (HDL)-targeting therapies, including reconstituted HDL (rHDL), are attractive agents for treating dyslipidemia and atherosclerosis, as…”
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Spiroimidazolidinone NPC1L1 inhibitors. 1: Discovery by 3D-similarity-based virtual screening by McMasters, Daniel R., Garcia-Calvo, Margarita, Maiorov, Vladimir, McCann, Margaret E., Meurer, Roger D., Bull, Herbert G., Lisnock, JeanMarie, Howell, Kobporn L., DeVita, Robert J.

“…A series of spiroimidazolidinone NPC1L1 inhibitors was discovered by virtual screening of the Merck corporate sample repository using 3D-similarity-based…”
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A pharmacologic analysis of the action of platelet-activating factor in the induction of hindpaw edema in the rat by Goldenberg, M M, Meurer, R D

“…Platelet-activating factor (PAF), a phospholipid product of neutrophils, alveolar macrophages, monocytes, and platelets and an important mediator of…”
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The effect of calcium antagonists on contractions of the sensitized and normal guinea pig ileum by Goldenberg, M M, Meurer, R D

“…The purpose of this study was to learn whether a number of Ca2+ antagonists were effective in reducing contractile responses of the isolated ileum of the…”
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