Search Results - "Meunier, Claude"

Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor by Meunier, Jean-Claude

“…Homology cloning and, more recently, the sequencing of whole genomes, have identified many open reading frames encoding proteins of unknown function, in…”
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Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity by Boeri, Juliette, Meunier, Claude, Le Corronc, Hervé, Branchereau, Pascal, Timofeeva, Yulia, Lejeune, François-Xavier, Mouffle, Christine, Arulkandarajah, Hervé, Mangin, Jean Marie, Legendre, Pascal, Czarnecki, Antonny

“…Renshaw cells (V1 ) are excitable as soon as they reach their final location next to the spinal motoneurons and are functionally heterogeneous. Using multiple…”
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Effects of clonidine on diuretic response in ascitic patients with cirrhosis and activation of sympathetic nervous system by Lenaerts, Anne, Codden, Thierry, Meunier, Jean‐Claude, Henry, Jean‐Pol, Ligny, Gaston

“…The effects of the addition of clonidine to diuretics on the mobilization of ascites in the short term (diuretic response and requirement of diuretics) and the…”
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Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor by MEUNIER, J.-C, MOLLEREAU, C, MAZARGUIL, H, VASSART, G, PARMENTIER, M, COSTENTIN, J, TOLL, L, SUAUDEAU, C, MOISAND, C, ALVINERIE, P, BUTOUR, J.-L, GUILLEMOT, J.-C, FERRARA, P, MONSARRAT, B

“…The ORL1 receptor, an orphan receptor whose human and murine complementary DNAs have recently been characterized, structurally resembles opioid receptors and…”
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The afterhyperpolarization conductance exerts the same control over the gain and variability of motoneurone firing in anaesthetized cats by Manuel, Marin, Meunier, Claude, Donnet, Maud, Zytnicki, Daniel

“…Does the afterhyperpolarization current control the gain and discharge variability of motoneurones according to the same law? We investigated this issue in…”
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Ligand-Regulated Internalization of the Opioid Receptor-Like 1: A Confocal Study by Corbani, Maithé, Gonindard, Christophe, Meunier, Jean-Claude

“…To better understand opioid receptor-like 1 (ORL1) internalization, we fused the C terminus of ORL1, the nociceptin (noc) receptor, to the N terminus of a…”
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Leukemic stem cell persistence in chronic myeloid leukemia patients with sustained undetectable molecular residual disease by Chomel, Jean-Claude, Bonnet, Marie-Laure, Sorel, Nathalie, Bertrand, Angelina, Meunier, Marie-Claude, Fichelson, Serge, Melkus, Michael, Bennaceur-Griscelli, Annelise, Guilhot, François, Turhan, Ali G.

“…Sustained undetectable molecular residual disease (UMRD) is obtained in a minority of patients with chronic myeloid leukemia treated with tyrosine kinase…”
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Autoradiographic localization of [ 3H]nociceptin binding sites in the rat brain by Florin, Sébastien, Meunier, Jean-Claude, Costentin, Jean

“…The binding sites of nociceptin (also named orphanin FQ), the endogenous ligand of ORL1 (opiate receptor like 1), were localized in rat brain, using an…”
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How membrane properties shape the discharge of motoneurons: a detailed analytical study by Meunier, Claude, Borejsza, Karol

“…Electrophysiological experiments and modeling studies have shown that afterhyperpolarization regulates the discharge of lumbar motoneurons in anesthetized cats…”
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Description of the low-affinity interaction between nociceptin and the second extracellular loop of its receptor by fluorescence and NMR spectroscopies by Vincent, Bruno, Mouledous, Lionel, Bes, Brice, Mazarguil, Honore, Meunier, Jean-Claude, Milon, Alain, Demange, Pascal

“…The second extracellular loop (ECL2) of the Noc receptor has been proposed to be involved in ligand binding and selectivity. The interaction of Noc with a…”
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Recognition and activation of the opioid receptor-like ORL1 receptor by nociceptin, nociceptin analogs and opioids by Butour, Jean-Luc, Moisand, Christiane, Mazarguil, Honore, Mollereau, Catherine, Meunier, Jean-Claude

“…Nociceptin, also known as orphanin FQ, was recently identified as the naturally occurring agonist of orphan opioid receptor-like ORL1 receptor (Meunier et al.,…”
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Identification of spectral modifications occurring during reprogramming of somatic cells by Sandt, Christophe, Féraud, Olivier, Oudrhiri, Noufissa, Bonnet, Marie Laure, Meunier, Marie Claude, Valogne, Yannick, Bertrand, Angelina, Raphaël, Martine, Griscelli, Frank, Turhan, Ali G, Dumas, Paul, Bennaceur-Griscelli, Annelise

“…Recent technological advances in cell reprogramming by generation of induced pluripotent stem cells (iPSC) offer major perspectives in disease modelling and…”
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Agonist-independent localization of the NOP receptor in detergent-resistant membrane rafts by Butour, Jean-Luc, Corbani, Maïthé, Meunier, Jean-Claude

“…A lipid rafts/detergent-resistant membrane (DRM) fraction was prepared from recombinant HEK293 cells stably expressing the human NOP receptor fused to the…”
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Functional inactivation of the nociceptin receptor by alanine substitution of glutamine 286 at the C terminus of transmembrane segment VI: evidence from a site-directed mutagenesis study of the ORL1 receptor transmembrane-binding domain by Mouledous, L, Topham, C M, Moisand, C, Mollereau, C, Meunier, J C

“…A site-directed mutagenesis approach has been used to gain insight into the molecular events whereby the heptadecapeptide nociceptin binds and activates the…”
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Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis by Neasta, Jérémie, Uttenweiler-Joseph, Sandrine, Chaoui, Karima, Monsarrat, Bernard, Meunier, Jean-Claude, Moulédous, Lionel

“…Opiate addiction reflects plastic changes that endurably alter synaptic transmission within relevant neuronal circuits. The biochemical mechanisms of these…”
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The nociceptin (ORL1) receptor: molecular cloning and functional architecture by Meunier, Jean-Claude, Mouledous, Lionel, Topham, Christopher M

“…Nociceptin and the ORL1 receptor share high sequence similarity with opioid peptides, particularly dynorphin A, and their receptors. However, nociceptin and…”
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Comparison of the structure-activity relationships of nociceptin and dynorphin A using chimeric peptides by Lapalu, Sophie, Moisand, Christiane, Mazarguil, Honoré, Cambois, Gilles, Mollereau, Catherine, Meunier, Jean-Claude

“…The aim of the present study was to delineate the functional domains of nociceptin (noc), a neuropeptide which is structurally related to dynorphin A (dyn)…”
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Direct Identification of a Peptide Binding Region in the Opioid Receptor-like 1 Receptor by Photoaffinity Labeling with [Bpa10,Tyr14]Nociceptin by Moulédous, Lionel, Topham, Christopher M., Mazarguil, Honoré, Meunier, Jean-Claude

“…The heptadecapeptide nociceptin, also known as orphanin FQ, is the endogenous agonist of the opioid receptor-like 1 (ORL1) G protein-coupled receptor. An…”
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Mixed mode oscillations in mouse spinal motoneurons arise from a low excitability state by Iglesias, Caroline, Meunier, Claude, Manuel, Marin, Timofeeva, Yulia, Delestrée, Nicolas, Zytnicki, Daniel

“…We explain the mechanism that elicits the mixed mode oscillations (MMOs) and the subprimary firing range that we recently discovered in mouse spinal…”
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Identification of a hexapeptide binding region in the nociceptin (ORL1) receptor by photo-affinity labelling with Ac-Arg-Bpa-Tyr-Arg-Trp-Arg-NH 2 by Bes, Brice, Meunier, Jean-Claude

“…The interaction of Ac-Arg-Tyr-Tyr-Arg-Trp-Arg-NH 2 (HP1), a high-affinity partial agonist of the opioid receptor like (ORL1) receptor, has been investigated…”
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