Search Results - "Meunier, Bernard"

Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer by Mariette, Christophe, Markar, Sheraz R, Dabakuyo-Yonli, Tienhan S, Meunier, Bernard, Pezet, Denis, Collet, Denis, D’Journo, Xavier B, Brigand, Cécile, Perniceni, Thierry, Carrère, Nicolas, Mabrut, Jean-Yves, Msika, Simon, Peschaud, Frédérique, Prudhomme, Michel, Bonnetain, Franck, Piessen, Guillaume

“…Open esophagectomy involves laparotomy and thoracotomy. Laparoscopic abdominal surgery may be useful for reducing complications, but does it control the…”
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Surgery Alone Versus Chemoradiotherapy Followed by Surgery for Stage I and II Esophageal Cancer: Final Analysis of Randomized Controlled Phase III Trial FFCD 9901 by MARIETTE, Christophe, DAHAN, Laetitia, BOSSET, Jean-François, MABRUT, Jean-Yves, TRIBOULET, Jean-Pierre, BEDENNE, Laurent, SEITZ, Jean-François, MORNEX, Françoise, MAILLARD, Emilie, THOMAS, Pascal-Alexandre, MEUNIER, Bernard, BOIGE, Valérie, PEZET, Denis, ROBB, William B, LE BRUN-LY, Valérie

“…Although often investigated in locally advanced esophageal cancer (EC), the impact of neoadjuvant chemoradiotherapy (NCRT) in early stages is unknown. The aim…”
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Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6) by Lefevre, Jérémie H, Mineur, Laurent, Kotti, Salma, Rullier, Eric, Rouanet, Philippe, de Chaisemartin, Cécile, Meunier, Bernard, Mehrdad, Jafari, Cotte, Eddy, Desrame, Jérome, Karoui, Mehdi, Benoist, Stéphane, Kirzin, Sylvain, Berger, Anne, Panis, Yves, Piessen, Guillaume, Saudemont, Alain, Prudhomme, Michel, Peschaud, Frédérique, Dubois, Anne, Loriau, Jérome, Tuech, Jean-Jacques, Meurette, Guillaume, Lupinacci, Renato, Goasgen, Nicolas, Parc, Yann, Simon, Tabassome, Tiret, Emmanuel

“…Purpose A pathologic complete response (pCR; ypT0N0) of a rectal tumor after neoadjuvant radiochemotherapy (RCT) is associated with an excellent prognosis…”
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Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial by Rullier, Eric, Prof, Rouanet, Philippe, Prof, Tuech, Jean-Jacques, Prof, Valverde, Alain, MD, Lelong, Bernard, Prof, Rivoire, Michel, Prof, Faucheron, Jean-Luc, Prof, Jafari, Mehrdad, Prof, Portier, Guillaume, Prof, Meunier, Bernard, Prof, Sileznieff, Igor, Prof, Prudhomme, Michel, Prof, Marchal, Frédéric, Prof, Pocard, Marc, Prof, Pezet, Denis, Prof, Rullier, Anne, MD, Vendrely, Véronique, MD, Denost, Quentin, MD, Asselineau, Julien, PhD, Doussau, Adélaïde, MD

“…Summary Background Organ preservation is a concept proposed for patients with rectal cancer after a good clinical response to neoadjuvant chemotherapy, to…”
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Guanine Oxidation: One- and Two-Electron Reactions by Pratviel, Geneviève, Meunier, Bernard

“…Guanine bases in DNA are the most sensitive to oxidation. A lot of effort has been devoted to the understanding of the chemical modifications of guanine under…”
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Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes by Meunier, Bernard, de Visser, Samuël P, Shaik, Sason

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Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma by Sulpice, Laurent, Rayar, Michel, Desille, Mireille, Turlin, Bruno, Fautrel, Alain, Boucher, Eveline, Llamas‐Gutierrez, Francisco, Meunier, Bernard, Boudjema, Karim, Clément, Bruno, Coulouarn, Cédric

“…Intrahepatic cholangiocarcinoma (ICC) is the second most common type of primary cancer in the liver. ICC is an aggressive cancer with poor prognosis and…”
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Age and Alzheimer's Disease by Meunier, Bernard

“…A recent review article published in Nutrients by Brewer [1] attracted the attention of the readers on the role of copper toxicity as major factor in…”
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Structures of the Copper and Zinc Complexes of PBT2, a Chelating Agent Evaluated as Potential Drug for Neurodegenerative Diseases by Nguyen, Michel, Vendier, Laure, Stigliani, Jean‐Luc, Meunier, Bernard, Robert, Anne

“…Clioquinol and PBT2, based on a 8‐hydroxyquinoline scaffold, have been proposed as drugs able to treat the disruption of metal homeostasis in neurodegenerative…”
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Copper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse model by Ceccom, Johnatan, Coslédan, Frédéric, Halley, Hélène, Francès, Bernard, Lassalle, Jean Michel, Meunier, Bernard

“…Alzheimer's disease (AD) is a neurodegenerative syndrom involving many different biological parameters, including the accumulation of copper metal ions in Aβ…”
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Why Is Tetradentate Coordination Essential for Potential Copper Homeostasis Regulators in Alzheimer's Disease? by Li, Youzhi, Nguyen, Michel, Baudoin, Morgane, Vendier, Laure, Liu, Yan, Robert, Anne, Meunier, Bernard

“…Research of effective drugs against Alzheimer's disease (AD) is currently one of the most challenging topics in medicinal chemistry. Despite the documented…”
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The Specific Copper(II) Chelator TDMQ20 Is Efficient for the Treatment of Wilson's Disease in Mice by Zhu, Yingshan, Tang, Ying, Huang, Lan, Nguyen, Michel, Liu, Yan, Robert, Anne, Meunier, Bernard

“…(1) Background: In patients with Wilson's disease, the deficiency of the copper carrier ATP7B causes the accumulation of copper in the liver, brain and various…”
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Stump closure reinforcement with absorbable fibrin collagen sealant sponge (TachoSil) does not prevent pancreatic fistula after distal pancreatectomy: the FIABLE multicenter controlled randomized study by Sa Cunha, Antonio, M.D., Ph.D, Carrere, Nicolas, M.D., Ph.D, Meunier, Bernard, M.D., Ph.D, Fabre, Jean-Michel, M.D, Sauvanet, Alain, M.D, Pessaux, Patrick, M.D., Ph.D, Ortega-Deballon, Pablo, M.D., Ph.D, Fingerhut, Abe, M.D, Lacaine, François, M.D., Ph.D

“…Abstract Background The aim of this study is to evaluate the effectiveness of TachoSil sponge on distal pancreatectomy remnant stump in reducing the rate and…”
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Preparation of Tetradentate Copper Chelators as Potential Anti‐Alzheimer Agents by Zhang, Weixin, Huang, Daya, Huang, Meijie, Huang, Ju, Wang, Dean, Liu, Xingguo, Nguyen, Michel, Vendier, Laure, Mazères, Serge, Robert, Anne, Liu, Yan, Meunier, Bernard

“…The uncontrolled redox activity of metal ions, especially copper, in the brains of patients with Alzheimer's disease (AD) should be considered the origin of…”
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Metalloporphyrins as versatile catalysts for oxidation reactions and oxidative DNA cleavage by Meunier, Bernard

“…It is shown that metalloporphytins are very versatile oxidation catalysts that can be used in many different oxidation reactions. Recent data on the catalytic…”
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Open versus laparoscopically-assisted oesophagectomy for cancer: a multicentre randomised controlled phase III trial - the MIRO trial by Briez, Nicolas, Piessen, Guillaume, Bonnetain, Franck, Brigand, Cécile, Carrere, Nicolas, Collet, Denis, Doddoli, Christophe, Flamein, Renaud, Mabrut, Jean-Yves, Meunier, Bernard, Msika, Simon, Perniceni, Thierry, Peschaud, Frédérique, Prudhomme, Michel, Triboulet, Jean-Pierre, Mariette, Christophe

“…Open transthoracic oesophagectomy is the standard treatment for infracarinal resectable oesophageal carcinomas, although it is associated with high mortality…”
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Selection of a trioxaquine as an antimalarial drug candidate by Coslédan, Frédéric, Fraisse, Laurent, Pellet, Alain, Guillou, François, Mordmüller, Benjamin, Kremsner, Peter G, Moreno, Alicia, Mazier, Dominique, Maffrand, Jean-Pierre, Meunier, Bernard

“…Trioxaquines are antimalarial agents based on hybrid structures with a dual mode of action. One of these molecules, PA1103/SAR116242, is highly active in vitro…”
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Distribution in Rat Blood and Brain of TDMQ20, a Copper Chelator Designed as a Drug-Candidate for Alzheimer's Disease by Huang, Lan, Zeng, Yaoxun, Li, Yongliang, Zhu, Yingshan, He, Yan, Liu, Yan, Robert, Anne, Meunier, Bernard

“…(1) Background: TDMQ20 is a specific regulator of copper homeostasis in the brain, able to inhibit cognitive impairment in the early stages of Alzheimer's…”
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Is signet-ring cell carcinoma a specific entity among gastric cancers? by Voron, Thibault, Messager, Mathieu, Duhamel, Alain, Lefevre, Jérémie, Mabrut, Jean-Yves, Goere, Diane, Meunier, Bernard, Brigand, Cecile, Hamy, Antoine, Glehen, Olivier, Mariette, Christophe, Paye, François

“…Background The prognosis and chemoresistance of signet-ring cell (SRC) gastric adenocarcinoma have been reported and debated, and the utility of perioperative…”
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Epithelial cell adhesion molecule is a prognosis marker for intrahepatic cholangiocarcinoma by Sulpice, Laurent, MD, PhD, Rayar, Michel, MD, Turlin, Bruno, MD, PhD, Boucher, Eveline, MD, Bellaud, Pascale, MD, Desille, Mireille, PhD, Meunier, Bernard, MD, Clément, Bruno, PhD, Boudjema, Karim, MD, PhD, Coulouarn, Cédric, PhD

“…Abstract Background Recently, we identified a gene signature of intrahepatic cholangiocarcinoma (ICC) stroma and demonstrated its clinical relevance for…”
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