Search Results - "Meuleman, Theodorus J"

Engineering a scalable and orthogonal platform for synthetic communication in mammalian cells by Makri Pistikou, Anna-Maria, Cremers, Glenn A. O., Nathalia, Bryan L., Meuleman, Theodorus J., Bögels, Bas W. A., Eijkens, Bruno V., de Dreu, Anne, Bezembinder, Maarten T. H., Stassen, Oscar M. J. A., Bouten, Carlijn C. V., Merkx, Maarten, Jerala, Roman, de Greef, Tom F. A.

“…The rational design and implementation of synthetic mammalian communication systems can unravel fundamental design principles of cell communication circuits…”
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Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis by Liu, Yongsheng, Güler, Rezan, Liao, Yunqi, Vorobyeva, Anzhelika, Widmark, Olof, Meuleman, Theodorus J, Koijen, Anna, van den Bos, Leendert J, Naasz, Robert, Bodenko, Vitalina, Orlova, Anna, Ekblad, Caroline, Tolmachev, Vladimir, Frejd, Fredrik Y

“…Targeted molecular radiation therapy is a promising emerging treatment modality in oncology, and peptide synthesis may shorten the time to reach the clinical…”
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Design and Synthesis of HCV-E2 Glycoprotein Epitope Mimics in Molecular Construction of Potential Synthetic Vaccines by Meuleman, Theodorus J, Cowton, Vanessa M, Patel, Arvind H, Liskamp, Rob M J

“…Hepatitis C virus remains a global threat, despite the availability of highly effective direct-acting antiviral (DAA) drugs. With thousands of new infections…”
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Immobilization by Surface Conjugation of Cyclic Peptides for Effective Mimicry of the HCV-Envelope E2 Protein as a Strategy toward Synthetic Vaccines by Meuleman, Theodorus J, Dunlop, James I, Owsianka, Anna M, van de Langemheen, Helmus, Patel, Arvind H, Liskamp, Rob M. J

“…Mimicry of the binding interface of antibody–antigen interactions using peptide-based modulators (i.e., epitope mimics) has promising applications for vaccine…”
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Improving the aqueous solubility of HCV‐E2 glycoprotein epitope mimics by cyclization using POLAR hinges by Meuleman, Theodorus J., Cowton, Vanessa M., Patel, Arvind H., Liskamp, Rob M.J.

“…In this research we describe the improvement of the water‐solubility of cyclic epitope mimics based on the HCV E2 glycoprotein by incorporation of suitable…”
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Approaches Towards Molecular Construction of a Synthetic Vaccine Against Hepatitis C Virus by Meuleman, Theodorus J

“…In this work, an alternative strategy involving a fully synthetic approach is being investigated toward structure-based vaccine design against HCV. The main…”
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