Search Results - "Meuer, Stefan C."

Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo by Nuhn, Philipp, Künzli, Beat M, Hennig, René, Mitkus, Tomas, Ramanauskas, Tadas, Nobiling, Rainer, Meuer, Stefan C, Friess, Helmut, Berberat, Pascal O

“…Pancreatic cancer (PaCa) is a fatal human cancer due to its exceptional resistance to all current anticancer therapies. The cytoprotective enzyme heme…”
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Molecular detection of breast cancer metastasis in sentinel lymph nodes by reverse transcriptase polymerase chain reaction (RT-PCR): identifying, evaluating and establishing multi-marker panels by Wallwiener, Christian W., Wallwiener, Markus, Kurth, Ralf R., Röhm, Carmen, Neubauer, Hans, Banys, Malgorzata J., Staebler, Annette, Schönfisch, Birgitt, Meuer, Stefan C., Giese, Thomas, Fehm, Tanja N.

“…The potential advantage of using quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) methodology to detect metastasis in sentinel lymph…”
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Cofilin Peptide Homologs Interfere with Immunological Synapse Formation and T Cell Activation by Eibert, Sybille M., Lee, Kyeong-Hee, Pipkorn, Rüdiger, Sester, Urban, Wabnitz, Guido H., Giese, Thomas, Meuer, Stefan C., Samstag, Yvonne, Schlossman, Stuart F.

“…The formation of supramolecular activation clusters within the immunological synapse, crucial for sustained signaling and T lymphocyte activation, requires…”
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Chinese‐German Cooperation Group Tumor Immunology: Another inspiring Meeting in Deidesheim by Kabelitz, Dieter, Cao, Xuetao, Tian, Zhigang, Meuer, Stefan C.

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Pharmacodynamic cyclosporine A-monitoring: relation of gene expression in lymphocytes to cyclosporine blood levels in cardiac allograft recipients by Konstandin, Mathias H, Sommerer, Claudia, Doesch, Andreas, Zeier, Martin, Meuer, Stefan C, Katus, Hugo A, Dengler, Thomas J, Giese, Thomas

“…Recently, we established a pharmacodynamic assay to monitor immunosuppressive effectiveness of cyclosporine A (CsA) in patients on standard CsA regimen. The…”
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In Situ Expression of Interleukin-10 in Noninflamed Human Gut and in Inflammatory Bowel Disease by Autschbach, Frank, Braunstein, Jutta, Helmke, Burkhard, Zuna, Ivan, Schürmann, Guido, Niemir, Zofia I., Wallich, Reinhard, Otto, Herwart F., Meuer, Stefan C.

“…A dysregulated secretion of contra-inflammatory cytokines such as interleukin-10 (IL-10) could play a role in the pathogenesis of inflammatory bowel disease…”
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Potential role of thioredoxin in immune responses in intestinal lamina propria T lymphocytes by Sido, Bernd, Giese, Thomas, Autschbach, Frank, Lasitschka, Felix, Braunstein, Jutta, Meuer, Stefan C.

“…Thioredoxin (TRX) is a ubiquitous oxidoreductase with strong co‐cytokine, chemoattractant and anti‐apoptotic activities. TRX expression was found to be…”
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Expression of interleukin‐12‐related cytokine transcripts in inflammatory bowel disease: Elevated interleukin‐23p19 and interleukin‐27p28 in Crohn's disease but not in ulcerative colitis by Schmidt, Carsten, Giese, Thomas, Ludwig, Bianca, Mueller‐Molaian, Ina, Marth, Thomas, Zeuzem, Stefan, Meuer, Stefan C., Stallmach, Andreas

“…Background: It has been suggested that Crohn's disease (CD) is associated with an exaggerated T‐helper 1 cytokine response manifested by increased production…”
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Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn's disease by STALLMACH, Andreas, GIESE, Thomas, SCHMIDT, Carsten, LUDWIG, Bianca, MUELLER-MOLAIAN, Ina, MEUER, Stefan C

“…Immunoregulatory properties of cytokines may contribute to pathological immune reactions in inflammatory bowel disease. There is an urgent need for a simple…”
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Human monocytes downregulate innate response receptors following exposure to the microbial metabolite n‐butyrate by Lasitschka, Felix, Giese, Thomas, Paparella, Marco, Kurzhals, Stefan R., Wabnitz, Guido, Jacob, Katrin, Gras, Judith, Bode, Konrad A., Heninger, Anne‐Kristin, Sziskzai, Timea, Samstag, Yvonne, Leszinski, Cornelia, Jocher, Bettina, Al‐Saeedi, Mohammed, Meuer, Stefan C., Schröder‐Braunstein, Jutta

“…Introduction Hyporesponsiveness of human lamina propria immune cells to microbial and nutritional antigens represents one important feature of intestinal…”
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The serine phosphatases PP1 and PP2A associate with and activate the actin‐binding protein cofilin in human T lymphocytes by Ambach, Andreas, Saunus, Jochen, Konstandin, Mathias, Wesselborg, Sebastian, Meuer, Stefan C., Samstag, Yvonne

“…Cofilin, an actin‐depolymerizing protein, is essential for the functional dynamics of the actin cytoskeleton and for cell viability. In unstimulated human…”
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Predictive value of mucosal TNF‐α transcripts in steroid‐refractory Crohn's disease patients receiving intensive immunosuppressive therapy by Schmidt, Carsten, Giese, Thomas, Hermann, Eva, Zeuzem, Stefan, Meuer, Stefan C., Stallmach, Andreas

“…Background: Concentrations of proinflammatory cytokines are increased in the intestinal mucosa of patients with active Crohn's disease (CD). In a prospective…”
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A Prominent Role for Mucosal Cystine/Cysteine Metabolism in Intestinal Immunoregulation by Sido, Bernd, Lasitschka, Felix, Giese, Thomas, Gassler, Nikolaus, Funke, Benjamin, Schröder–Braunstein, Jutta, Brunnemer, Ulf, Meuer, Stefan C, Autschbach, Frank

“…Background & Aims: T-cell receptor reactivity of intestinal lamina propria T cells (LP-T) critically depends on the capacity of local accessory cells to…”
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Severe anaphylactic reaction to infliximab: successful treatment with adalimumab – report of a case by Stallmach, Andreas, Giese, Thomas, Schmidt, Carsten, Meuer, Stefan C, Zeuzem, Stefan S

“…Treatment with the anti-tumour necrosis factor alpha chimeric monoclonal antibody infliximab is highly effective in the treatment of refractory and fistulising…”
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Dephosphorylation of Serine 3 Regulates Nuclear Translocation of Cofilin by Nebl, G, Meuer, S C, Samstag, Y

“…Signal transduction processes in T-cells and other cell types alter the phosphorylation state of cofilin, an actin-binding phosphoprotein. Whether reversible…”
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Activation of β1 integrins mediates proliferation and inhibits apoptosis of intestinal CD4‐positive lymphocytes by Stallmach, Andreas, Giese, Thomas, Pfister, Kerstin, Wittig, Bianca M., Künne, Sven, Humphries, Martin, Zeitz, Martin, Meuer, Stefan C.

“…A characteristic of lamina propria lymphocytes (LPL) is their low proliferative response to stimuli of the CD3 pathway. β1 integrins were expressed on LPL;…”
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Differential effects on innate versus adaptive immune responses by WF10 by Giese, Thomas, McGrath, Michael S., Stumm, Susanne, Schempp, Harald, Elstner, Erich, Meuer, Stefan C.

“…Oxidative compounds that are physiologically generated in vivo can induce natural defense mechanisms to enhance the elimination of pathogens and to limit…”
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Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn's disease by AUTSCHBACH, Frank, GIESE, Thomas, OTTO, Herwart F, MEUER, Stefan C, GASSLER, Nikolaus, SIDO, Bernd, HEUSCHEN, Gundi, HEUSCHEN, Udo, ZUNA, Ivan, SCHULZ, Patricia, WECKAUF, Helgard, BERGER, Irina

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Association of CD2 and CD45 on human T lymphocytes by Schraven, Burkhart, Samstag, Yvonne, Altevogt, Peter, Meuer, Stefan C

“…At least two membrane receptors have been defined through which human T lymphocytes can be induced to proliferate and differentiate, namely the CD3-Ti antigen…”
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Expression of different CD8 isoforms on distinct human lymphocyte subpopulations by Moebius, U, Kober, G, Griscelli, A L, Hercend, T, Meuer, S C

“…Human CD8+ lymphocyte subpopulations were analyzed for their expression of CD8 alpha and CD8 beta subunits. Investigations with uncloned peripheral blood…”
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