Search Results - "Metzner, H. J."

International comparative field study evaluating the assay performance of AFSTYLA in plasma samples at clinical hemostasis laboratories by St. Ledger, K., Feussner, A., Kalina, U., Horn, C., Metzner, H. J., Bensen‐Kennedy, D., Blackman, N., Veldman, A., Stowers, A., Friedman, K. D.

“…Essentials AFSTYLA exhibits ≈50% underestimation in activity when the one‐stage (OS) assay is utilized. A field study compared the performance of AFSTYLA with…”
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Extending the pharmacokinetic half-life of coagulation factors by fusion to recombinant albumin by Metzner, H J, Pipe, S W, Weimer, T, Schulte, S

“…The prophylactic treatment of haemophilia B and the management of haemophilia A or B with inhibitors demand frequent administrations of coagulation factors due…”
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Characterization of factor VIII/von Willebrand factor concentrates using a modified method of von Willebrand factor multimer analysis by Metzner, H J, Hermentin, P, Cuesta-Linker, T, Langner, S, Müller, H G, Friedebold, J

“…In order to provide patients with von Willebrand disease a factor VIII (FVIII)/von Willebrand factor (vWF) concentrate of reproducible quality, an SDS‐agarose…”
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Two non-proline cis peptide bonds may be important for factor XIII function by Weiss, Manfred S, Metzner, Hubert J, Hilgenfeld, Rolf

“…The structure of recombinant human cellular factor XIII zymogen was solved in its monoclinic crystal form and refined to an R-factor of 18.3% ( R free=23.6%)…”
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Effect of factor XIII on endothelial barrier function by Noll, T, Wozniak, G, McCarson, K, Hajimohammad, A, Metzner, H J, Inserte, J, Kummer, W, Hehrlein, F W, Piper, H M

“…The effect of factor XIII on endothelial barrier function was studied in a model of cultured monolayers of porcine aortic endothelial cells and saline-perfused…”
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Crystallization of blood coagulation factor XIII by an automated procedure by Hilgenfeld, Rolf, Liesum, Alexander, Storm, Rüdiger, Metzner, Hubert J., Karges, Hermann E.

“…Both recombinant blood coagulation factor XIII a-chain and factor XIII isolated from human placenta have been crystallized using a novel robotic system for the…”
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Determination of High-Molecular-Weight von Willebrand factor multimers and their impact on specific VWF-activities in VWF/FVIII-concentrates by Walter, O., Budde, U., Muysers, C., Metzner, H. J., Suiter, T. M.

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Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: hemostatic abnormalities in mutant mice and characterization of the coagulation deficit by Lauer, Peter, Metzner, Hubert J, Zettlmeissl, Gerd, Li, Meng, Smith, Austin G, Lathe, Richard, Dickneite, Gerhard

“…Blood coagulation factor XIII (FXIII) promotes cross-linking of fibrin during blood coagulation; impaired clot stabilization in human genetic deficiency is…”
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Therapeutic factor XIII preparations and perspectives for recombinant factor XIII by Karges, H E, Metzner, H J

“…With the increasing availability of human plasma this source was used to substitute for the production of factor XIII concentrate from placenta. Prior to…”
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The Importance of Factor XIII as a Component of Fibrin Sealants by Dickneite, Gerhard, Metzner, Hubert J., Kroez, Monika, Hein, Berndt, Nicolay, Uwe

“…Background. The need for factor XIII (FXIII) in fibrin sealant is subject to discussions. Some commercially available fibrin sealants (FS) contain high levels…”
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