Search Results - "Metzler‐Nolte, Nils"
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Iridium(I) Compounds as Prospective Anticancer Agents: Solution Chemistry, Antiproliferative Profiles and Protein Interactions for a Series of Iridium(I) N-Heterocyclic Carbene Complexes
Published in Chemistry : a European journal (22-08-2016)“…A series of structurally related mono‐ and bis‐NHC–iridium(I) (NHC: N‐heterocyclic carbene) complexes have been investigated for their suitability as potential…”
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Synthetic Approaches towards Peptide‐Conjugates of Pt(II) Compounds with an (O,S) Chelating Moiety
Published in European journal of inorganic chemistry (20-12-2023)“…Metal‐containing peptide (bio−)conjugates have received continuous interest due to their enormous potential for bioinorganic and medicinal research. In many…”
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3
Vectorization via Siderophores Increases Antibacterial Activity of K(RW) 3 Peptides against Pseudomonas aeruginosa
Published in Chemistry : a European journal (06-09-2023)“…A series of new conjugates comprised from a small synthetic antimicrobial peptide (AMP) and a siderophore-type vector component was designed and tested for…”
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4
Unveiling Luminescent IrI and RhI N‐Heterocyclic Carbene Complexes: Structure, Photophysical Specifics, and Cellular Localization in the Endoplasmic Reticulum
Published in Chemistry : a European journal (16-04-2021)“…Complexes of RhI and IrI of the [M(COD)(NHC)X] type (where M=Rh or Ir, COD=1,5‐cyclooctadiene, NHC=N‐heterocyclic carbene, and X=halide) have recently shown…”
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Cytotoxic Activity of Some Half‐sandwich Rhodium(III) Complexes Containing 4,4’‐disubstituted‐2,2’‐bipyridine Ligands
Published in Zeitschrift für anorganische und allgemeine Chemie (1950) (02-01-2024)“…The synthesis and characterization of three compounds [Rh(η5‐C5Me5)Cl(N^N)]PF6 (N^N=4,4’‐disubstituted‐2,2’‐bipyridines, 1–3) are described. The cationic…”
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6
Iron Metal-Organic Frameworks MIL-88B and NH2-MIL-88B for the Loading and Delivery of the Gasotransmitter Carbon Monoxide
Published in Chemistry : a European journal (17-05-2013)“…Crystals of MIL‐88B‐Fe and NH2‐MIL‐88B‐Fe were prepared by a new rapid microwave‐assisted solvothermal method. High‐purity, spindle‐shaped crystals of…”
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7
Label-Free Imaging of Metal-Carbonyl Complexes in Live Cells by Raman Microspectroscopy
Published in Angewandte Chemie (International ed.) (26-04-2010)“…A new kid in town: 3D Raman intensity images of a HT29 colon cancer cell incubated with an aqueous solution of the CO‐releasing metal–carbonyl complex 1 show…”
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Synthesis, Characterization and Cytotoxic Activities of Half‐sandwich Pentamethylcyclopentadienyl Iridium(III) Complexes Containing 4,4'‐substituted 2,2'‐Bipyridine Ligands
Published in Zeitschrift für anorganische und allgemeine Chemie (1950) (14-03-2023)“…The synthesis and characterization of six new organometallic half‐sandwich iridium(III) compounds containing modified 4,4'‐substituted 2,2'‐bipyridines as the…”
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9
Siderophore‐Linked Ruthenium Catalysts for Targeted Allyl Ester Prodrug Activation within Bacterial Cells
Published in Chemistry : a European journal (07-02-2023)“…Due to rising resistance, new antibacterial strategies are needed, including methods for targeted antibiotic release. As targeting vectors, chelating molecules…”
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10
Biometal Corrole Active Esters and Their Amino Acid and Peptide Conjugates
Published in European journal of inorganic chemistry (31-08-2020)“…The synthesis of a series of A2B‐corroles with 4‐carboxyphenyl substituent is described. The macrocycles are prepared from dipyrromethanes and 4‐formylbenzoic…”
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Cytotoxic Activities of Half‐sandwich M(III) Complexes (M=Rh, Ir) Bearing Chloro‐substituted Bidentate‐coordinated Phenanthroline or Terpyridine Ligands
Published in Zeitschrift für anorganische und allgemeine Chemie (1950) (01-08-2023)“…The synthesis and characterization of four compounds [M(η5‐C5Me5)(N^N)Cl]PF6 [N^N=4,7‐dichloro‐1,10‐phenanthroline with M=Rh, 1, and M=Ir, 2, and…”
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Cytotoxic Activities of Bis‐cyclometalated M(III) Complexes (M=Rh, Ir) Containing 5‐substituted 1,10‐Phenanthroline or 4,4’‐substituted 2,2’‐Bipyridine Ligands
Published in Zeitschrift für anorganische und allgemeine Chemie (1950) (15-11-2022)“…The synthesis and characterization of eight new bis‐cyclometalated compounds [M(ptpy)2(N^N)]PF6 (ptpy=2‐(p‐tolyl)pyridinato; N^N=5‐chloro‐1,10‐phenanthroline:…”
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Luminescent Bimetallic IrIII/AuI Peptide Bioconjugates as Potential Theranostic Agents
Published in Chemistry : a European journal (21-09-2020)“…Diverse iridium peptide bioconjugates and the corresponding iridium/gold bimetallic complexes have been synthesized starting from a cyclometallated carboxylic…”
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Structural Insights into Antibacterial Payload Release from Gold Nanoparticles Bound to E. coli Peptide Deformylase
Published in ChemMedChem (15-03-2024)“…The lack of new antibiotics and the rapidly rising number of pathogens resistant to antibiotics pose a serious problem to mankind. In bacteria, the cell…”
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15
A Solid Support‐Based Synthetic Strategy for the Site‐Selective Functionalization of Peptides with Organometallic Half‐Sandwich Moieties
Published in Chemistry : a European journal (24-02-2022)“…The number of donor atoms available on peptides that can competitively coordinate to metal centers renders the site‐selective generation of advanced…”
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A Remarkably Simple Class of Imidazolium-Based Lipids and Their Biological Properties
Published in Chemistry : a European journal (19-10-2015)“…A series of imidazolium salts bearing two alkyl chains in the backbone of the imidazolium core were synthesized, resembling the structure of lipids. Their…”
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A Reinvestigation of the Role of the Sorbic Acid Tail on the Antibacterial and Anti‐Tuberculosis Properties of Moiramide B
Published in ChemMedChem (01-06-2023)“…Due to worldwide increasing resistances, there is a considerable need for antibacterial compounds with modes of action not yet realized in commercial…”
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Metal and Substituent Influence on the Cytostatic Activity of Cationic Bis‐cyclometallated Iridium and Rhodium Complexes with Substituted 1,10‐Phenanthrolines as Ancillary Ligands
Published in Zeitschrift für anorganische und allgemeine Chemie (1950) (15-07-2020)“…Synthesis and characterization of the new cyclometalated complex salts [Rh(ptpy)2(5.6‐dimethyl‐1,10‐phenanthroline)]PF6 (1a)…”
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Luminescent Bimetallic IrIII/AuI Peptide Bioconjugates as Potential Theranostic Agents
Published in Chemistry : a European journal (21-09-2020)“…Invited for the cover of this issue are Vanesa Fernández‐Moreira, Nils Metzler‐Nolte, M. Concepción Gimeno and co‐workers at Universidad de Zaragoza and…”
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20
Bis‐cyclometalated Rhodium and Iridium Chloride Complexes Yield Different Products Upon Reaction With 9,10‐Diaminophenanthrene
Published in Zeitschrift für anorganische und allgemeine Chemie (1950) (13-09-2019)“…The reaction of 9.10‐diaminophenanthrene with [{Rh(μ‐Cl)(ptpy)2}2] yields – quite unexpected – the new cyclometalated complex salts…”
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