Search Results - "Metzler, Kathleen D."

A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis by Metzler, Kathleen D., Goosmann, Christian, Lubojemska, Aleksandra, Zychlinsky, Arturo, Papayannopoulos, Venizelos

“…Neutrophils contain granules loaded with antimicrobial proteins and are regarded as impermeable organelles that deliver cargo via membrane fusion. However,…”
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Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps by Papayannopoulos, Venizelos, Metzler, Kathleen D., Hakkim, Abdul, Zychlinsky, Arturo

“…Neutrophils release decondensed chromatin termed neutrophil extracellular traps (NETs) to trap and kill pathogens extracellularly. Reactive oxygen species are…”
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Neutrophil Function: From Mechanisms to Disease by Amulic, Borko, Cazalet, Christel, Hayes, Garret L, Metzler, Kathleen D, Zychlinsky, Arturo

“…Neutrophils are the most abundant white blood cells in circulation, and patients with congenital neutrophil deficiencies suffer from severe infections that are…”
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Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity by Metzler, Kathleen D., Fuchs, Tobias A., Nauseef, William M., Reumaux, Dominique, Roesler, Joachim, Schulze, Ilka, Wahn, Volker, Papayannopoulos, Venizelos, Zychlinsky, Arturo

“…The granule enzyme myeloperoxidase (MPO) plays an important role in neutrophil antimicrobial responses. However, the severity of immunodeficiency in patients…”
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Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps by Papayannopoulos, Venizelos, Metzler, Kathleen D., Hakkim, Abdul, Zychlinsky, Arturo

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