Search Results - "Metzger, Ryan R."

Visual- and saccade-related signals in the primate inferior colliculus by Porter, Kristin Kelly, Metzger, Ryan R, Groh, Jennifer M

“…The inferior colliculus (IC) is normally thought of as a predominantly auditory structure because of its early position in the ascending auditory pathway just…”
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Risk of natalizumab-associated PML in patients with MS is reduced with extended interval dosing by Ryerson, Lana Zhovtis, Foley, John, Chang, Ih, Kister, Ilya, Cutter, Gary, Metzger, Ryan R, Goldberg, Judith D, Li, Xiaochun, Riddle, Evan, Smirnakis, Karen, Kasliwal, Rachna, Ren, Zheng, Hotermans, Christophe, Ho, Pei-Ran, Campbell, Nolan

“…OBJECTIVETo use the large dataset from the Tysabri OutreachUnified Commitment to Health (TOUCH) program to compare progressive multifocal leukoencephalopathy…”
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Effects of Reward and Behavioral Context on Neural Activity in the Primate Inferior Colliculus by Metzger, Ryan R, Greene, Nathaniel T, Porter, Kristin Kelly, Groh, Jennifer M

“…Neural activity in the inferior colliculus (IC) likely plays an integral role in the processing of various auditory parameters, such as sound location and…”
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Evaluation of natalizumab pharmacokinetics and pharmacodynamics with standard and extended interval dosing by Foley, John F., Goelz, Susan, Hoyt, Tamara, Christensen, Angelene, Metzger, Ryan R.

“…•Natalizumab blood levels vary considerably among patients receiving standard dosing.•Body weight, age, and treatment duration impact blood levels at…”
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Use of Rotterdam CT scores for mortality risk stratification in children with traumatic brain injury by Liesemer, Kate, Riva-Cambrin, Jay, Bennett, Kimberly Statler, Bratton, Susan L, Tran, Henry, Metzger, Ryan R, Bennett, Tellen D

“…The Rotterdam CT score refined features of the Marshall score and was designed to categorize traumatic brain injury type and severity in adults. The objective…”
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Lessons learned after 20 years of real-world experience with natalizumab by Khatri, Bhupendra O., Olapo, Tayo, Beals, Sara, Lindman, Emily, Perea, Toni, Van Zealand, Pamela, Metzger, Ryan R

“…•The finding of 0 PML cases in our natalizumab treatment cohort was somewhat exceptional.•Frequent clinical evaluation may have contributed to the absence of…”
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Helicopter versus ground emergency medical services for the transportation of traumatically injured children by Stewart, Camille L, Metzger, Ryan R, Pyle, Laura, Darmofal, Joe, Scaife, Eric, Moulton, Steven L

“…Abstract Background Helicopter emergency medical services (HEMS) are a common mode of transportation for pediatric trauma patients. We hypothesized that HEMS…”
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The role of focused abdominal sonography for trauma (FAST) in pediatric trauma evaluation by Scaife, Eric R, Rollins, Michael D, Barnhart, Douglas C, Downey, Earl C, Black, Richard E, Meyers, Rebecka L, Stevens, Mark H, Gordon, Sasha, Prince, Jeffrey S, Battaglia, Deborah, Fenton, Stephen J, Plumb, Jennifer, Metzger, Ryan R

“…Abstract Purpose With increasing concerns about radiation exposure, we questioned whether a structured program of FAST might decrease CT use. Methods All…”
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Pharmacodynamics of natalizumab extended interval dosing in MS by Zhovtis Ryerson, Lana, Li, Xiaochun, Goldberg, Judith D., Hoyt, Tamara, Christensen, Angel, Metzger, Ryan R., Kister, Ilya, Foley, John

“…To determine if the concentration and saturation of natalizumab (NTZ) administration at extended interval dosing (EID; every 5-8 weeks) over 18 months is able…”
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Chair Lift Falls and Injuries in Children by Glissmeyer, Eric W, Metzger, Ryan R, Bolte, Robert

“…OBJECTIVEThe objective of this study was to compare demographic injury and treatment characteristics of hospitalized pediatric cases of falls from chair lifts…”
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Differential effects of psychostimulants and related agents on dopaminergic and serotonergic transporter function by Fleckenstein, Annette E, Haughey, Heather M, Metzger, Ryan R, Kokoshka, Jerry M, Riddle, Evan L, Hanson, Jarom E, Gibb, James W, Hanson, Glen R

“…High-dose administrations of amphetamine, methamphetamine, cathinone, methcathinone or methylenedioxymethamphetamine rapidly decrease dopamine and serotonin…”
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Preventable transfers in pediatric trauma: A 10-year experience at a level I pediatric trauma center by Fenton, Stephen J, Lee, Justin H, Stevens, Austin M, Kimbal, Kyle C, Zhang, Chong, Presson, Angela P, Metzger, Ryan R, Scaife, Eric R

“…Abstract Background Injured children are often treated at one facility then transferred to another that specializes in pediatric trauma care. The purpose of…”
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Cervical spine computed tomography utilization in pediatric trauma patients by Adelgais, Kathleen M, Browne, Lorin, Holsti, Maija, Metzger, Ryan R, Murphy, Shannon Cox, Dudley, Nanette

“…Abstract Background Guidelines for evaluating the cervical spine in pediatric trauma patients recommend cervical spine CT (CSCT) when plain radiographs suggest…”
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Risk factors for traumatic blunt cerebrovascular injury diagnosed by computed tomography angiography in the pediatric population: a retrospective cohort study by Ravindra, Vijay M, Riva-Cambrin, Jay, Sivakumar, Walavan, Metzger, Ryan R, Bollo, Robert J

“…OBJECT Computed tomography angiography (CTA) is frequently used to examine patients for blunt cerebrovascular injury (BCVI) after cranial trauma, but the…”
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Inhibitory effect of reserpine on dopamine transporter function by Metzger, Ryan R, Brown, Jeffrey M, Sandoval, Verónica, Rau, Kristi S, Elwan, Mohamed A, Miller, Gary W, Hanson, Glen R, Fleckenstein, Annette E

“…Previous studies indicate that reserpine may disrupt dopamine transporter activity. Results presented herein reveal that it also inhibits potently synaptosomal…”
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Impact of newly adopted guidelines for management of children with isolated skull fracture by Metzger, Ryan R, Smith, Julia, Wells, Matthew, Eldridge, Lesley, Holsti, Maija, Scaife, Eric R, Barnhart, Douglas C, Rollins, Michael D

“…Abstract Purpose In an effort to standardize practices and reduce unnecessary hospital resource utilization, we implemented guidelines for management of…”
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Temporal response profiles of serum ubiquitin C-terminal hydrolase-L1 and the 145-kDa alpha II-spectrin breakdown product after severe traumatic brain injury in children by Metzger, Ryan R, Sheng, Xiaoming, Niedzwecki, Christian M, Bennett, Kimberly S, Morita, Denise C, Zielinski, Brandon, Schober, Michelle E

“…Traumatic brain injury (TBI) is the leading cause of acquired disability among children. Brain injury biomarkers may serve as useful diagnostic and prognostic…”
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Alpha II Spectrin breakdown products in immature Sprague Dawley rat hippocampus and cortex after traumatic brain injury by Schober, Michelle E, Requena, Daniela F, Davis, Lizeth J, Metzger, Ryan R, Bennett, Kimberly S, Morita, Denise, Niedzwecki, Christian, Yang, Zhihui, Wang, Kevin K.W

“…Abstract After traumatic brain injury (TBI), proteolysis of Alpha II Spectrin by Calpain 1 produces 145 Spectrin breakdown products (SBDPs) while proteolysis…”
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High-dose barbiturates for refractory intracranial hypertension in children with severe traumatic brain injury by Mellion, Sarah A, Bennett, Kimberly Statler, Ellsworth, German L, Moore, Kevin, Riva-Cambrin, Jay, Metzger, Ryan R, Bratton, Susan L

“…To evaluate high-dose barbiturates as a second-tier therapy for pediatric refractory intracranial hypertension complicating severe traumatic brain injury. This…”
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Pediatric liver lacerations and intensive care: evaluation of ICU triage strategies by Fremgen, Heather E, Bratton, Susan L, Metzger, Ryan R, Barnhart, Douglas C

“…To compare PICU admission criteria following blunt traumatic liver laceration based on CT grade and/or physiologic instability with actual practice to improve…”
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