Search Results - "Mett, Vadim"

Optimization and utilization of Agrobacterium-mediated transient protein production in Nicotiana by Shamloul, Moneim, Trusa, Jason, Mett, Vadim, Yusibov, Vidadi

“…Agrobacterium-mediated transient protein production in plants is a promising approach to produce vaccine antigens and therapeutic proteins within a short…”
Get full text

Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody by Frescas, David, Roux, Christelle M., Aygun-Sunar, Semra, Gleiberman, Anatoli S., Krasnov, Peter, Kurnasov, Oleg V., Strom, Evguenia, Virtuoso, Lauren P., Wrobel, Michelle, Osterman, Andrei L., Antoch, Marina P., Mett, Vadim, Chernova, Olga B., Gudkov, Andrei V.

“…Studying the phenomenon of cellular senescence has been hindered by the lack of senescence-specific markers. As such, detection of proteins informally…”
Get full text

A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized mice by Jones, R Mark, Chichester, Jessica A, Mett, Vadim, Jaje, Jennifer, Tottey, Stephen, Manceva, Slobodanka, Casta, Louis J, Gibbs, Sandra K, Musiychuk, Konstantin, Shamloul, Moneim, Norikane, Joey, Mett, Valentina, Streatfield, Stephen J, van de Vegte-Bolmer, Marga, Roeffen, Will, Sauerwein, Robert W, Yusibov, Vidadi

“…Malaria transmission blocking vaccines (TBVs) are considered an effective means to control and eventually eliminate malaria. The Pfs25 protein, expressed…”
Get full text

Mitigation of Radiation-Induced Epithelial Damage by the TLR5 Agonist Entolimod in a Mouse Model of Fractionated Head and Neck Irradiation by Toshkov, Ilia A., Gleiberman, Anatoli S., Mett, Vadim L., Hutson, Alan D., Singh, Anurag K., Gudkov, Andrei V., Burdelya, Lyudmila G.

“…Radiation treatment of head and neck cancer frequently causes severe collateral damage to normal tissues including mouth mucosa, salivary glands and skin. This…”
Get full text

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients by Eremina, Natalia V, Kazey, Vasily I, Mishugin, Sergey V, Leonenkov, Roman V, Pushkar, Dmitry Y, Mett, Vadim L, Gudkov, Andrei V

“…Toll-like receptor 5 (TLR5) controls endogenous immune responses to pathogens and is a promising target for pharmacological stimulation of anti-tumor immunity…”
Get full text

A plant‐based system for rapid production of influenza vaccine antigens by Shoji, Yoko, Farrance, Christine E., Bautista, James, Bi, Hong, Musiychuk, Konstantin, Horsey, April, Park, HeeWoo, Jaje, Jennifer, Green, Brian J., Shamloul, Moneim, Sharma, Satish, Chichester, Jessica A., Mett, Vadim, Yusibov, Vidadi

“…Please cite this paper as: Shoji et al. (2011) A plant‐based system for rapid production of influenza vaccine antigens. Influenza and Other Respiratory Viruses…”
Get full text

A Plant-Produced Pfs230 Vaccine Candidate Blocks Transmission of Plasmodium falciparum by Farrance, Christine E, Rhee, Amy, Jones, R Mark, Musiychuk, Konstantin, Shamloul, Moneim, Sharma, Satish, Mett, Vadim, Chichester, Jessica A, Streatfield, Stephen J, Roeffen, Will, van de Vegte-Bolmer, Marga, Sauerwein, Robert W, Tsuboi, Takafumi, Muratova, Olga V, Wu, Yimin, Yusibov, Vidadi

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Production of non-glycosylated recombinant proteins in Nicotiana benthamiana plants by co-expressing bacterial PNGase F by Mamedov, Tarlan, Ghosh, Ananya, Jones, R Mark, Mett, Vadim, Farrance, Christine E, Musiychuk, Konstantin, Horsey, April, Yusibov, Vidadi

“…Application of tools of molecular biology and genomics is increasingly leading towards the development of recombinant protein-based biologics. As such, it is…”
Get more information

Plant-based rapid production of recombinant subunit hemagglutinin vaccines targeting H1N1 and H5N1 influenza by Shoji, Yoko, Chichester, Jessica A., Jones, Mark, Manceva, Slobodanka D., Damon, Emily, Mett, Vadim, Musiychuk, Konstantin, Bi, Hong, Farrance, Christine, Shamloul, Moneim, Kushnir, Natasha, Sharma, Satish, Yusibov, Vidadi

“…In 2009, a novel H1N1 swine influenza virus was isolated from infected humans in Mexico and the United States, and rapidly spread around the world. Another…”
Get full text

A deimmunized and pharmacologically optimized Toll-like receptor 5 agonist for therapeutic applications by Mett, Vadim, Kurnasov, Oleg V., Bespalov, Ivan A., Molodtsov, Ivan, Brackett, Craig M., Burdelya, Lyudmila G., Purmal, Andrei A., Gleiberman, Anatoli S., Toshkov, Ilia A., Burkhart, Catherine A., Kogan, Yakov N., Andrianova, Ekaterina L., Gudkov, Andrei V., Osterman, Andrei L.

“…The Toll-like receptor 5 (TLR5) agonist entolimod, a derivative of Salmonella flagellin, has therapeutic potential for several indications including…”
Get full text

A launch vector for the production of vaccine antigens in plants by Musiychuk, Konstantin, Stephenson, Natalie, Bi, Hong, Farrance, Christine E., Orozovic, Goran, Brodelius, Maria, Brodelius, Peter, Horsey, April, Ugulava, Natalia, Shamloul, Abdel‐Moneim, Mett, Vadim, Rabindran, Shailaja, Streatfield, Stephen J., Yusibov, Vidadi

“…Historically, most vaccines have been based on killed or live‐attenuated infectious agents. Although very successful at immunizing populations against disease,…”
Get full text

Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity by Farrance, Christine E., Chichester, Jessica A., Musiychuk, Konstantin, Shamloul, Moneim, Rhee, Amy, Manceva, Slobodanka D., Jones, R. Mark, Mamedov, Tarlan, Sharma, Satish, Mett, Vadim, Streatfield, Stephen J., Roeffen, Will, van de Vegte-Bolmer, Marga, Sauerwein, Robert W., Wu, Yimin, Muratova, Olga, Miller, Louis, Duffy, Patrick, Sinden, Robert, Yusibov, Vidadi

“…Malaria is a serious and sometimes fatal mosquito-borne disease caused by a protozoan parasite. Each year, it is estimated that over one million people are…”
Get full text

Transient protein expression in three Pisum sativum (green pea) varieties by Green, Brian J., Fujiki, Masaaki, Mett, Valentina, Kaczmarczyk, Jon, Shamloul, Moneim, Musiychuk, Konstantin, Underkoffler, Susan, Yusibov, Vidadi, Mett, Vadim

“…The expression of proteins in plants both transiently and via permanently transformed lines has been demonstrated by a number of groups. Transient plant…”
Get full text

A non-glycosylated, plant-produced human monoclonal antibody against anthrax protective antigen protects mice and non-human primates from B. anthracis spore challenge by Mett, Vadim, Chichester, Jessica A., Stewart, Michelle L., Musiychuk, Konstantin, Bi, Hong, Reifsnyder, Carolyn J., Hull, Anna K., Albrecht, Mark T., Goldman, Stanley, Baillie, Les W. J., Yusibov, Vidadi

“…The health and economic burden of infectious diseases in general and bioterrorism in particular necessitate the development of medical countermeasures. One…”
Get full text

An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses by Shoji, Yoko, Chichester, Jessica A., Palmer, Gene A., Farrance, Christine E., Stevens, Robert, Stewart, Michelle, Goldschmidt, Lauren, Deyde, Varough, Gubareva, Larisa, Klimov, Alexander, Mett, Vadim, Yusibov, Vidadi

“…H5N1 avian influenza continues to be a potential pandemic threat. Several vaccine candidates based on potentially pandemic influenza strains and antiviral…”
Get full text

Controlled cytokinin production in transgenic tobacco using a copper-inducible promoter by McKenzie, M.J, Mett, V, Reynolds, P.H.S, Jameson, P.E

“…The cytokinin group of plant hormones regulates aspects of plant growth and development, including the release of lateral buds from apical dominance and the…”
Get full text

Copper-controllable gene expression system for whole plants by Mett, V.L, Lochhead, L.P, Reynolds, P.H.S

“…We describe a system for gene expression in plants based on the regulation mechanism of the yeast metallothionein (MT) gene. The system consists of two…”
Get full text

Anti-cancer activity of plant-produced HPV16 E7 vaccine by Massa, Silvia, Franconi, Rosella, Brandi, Rossella, Muller, Antonio, Mett, Vadim, Yusibov, Vidadi, Venuti, Aldo

“…Abstract The E7 oncoprotein from Human Papilloma Virus (HPV) is an attractive candidate for anti-cancer vaccine development. In this study, we engineered HPV16…”
Get full text

Development of a Single-Replicon miniBYV Vector for Co-expression of Heterologous Proteins by Prokhnevsky, Alex, Mamedov, Tarlan, Leffet, Brett, Rahimova, Rahila, Ghosh, Ananya, Mett, Vadim, Yusibov, Vidadi

“…In planta production of recombinant proteins, including vaccine antigens and monoclonal antibodies, continues gaining acceptance. With the broadening range of…”
Get full text

Plant-expressed HA as a seasonal influenza vaccine candidate by Shoji, Yoko, Chichester, Jessica A, Bi, Hong, Musiychuk, Konstantin, de la Rosa, Patricia, Goldschmidt, Lauren, Horsey, April, Ugulava, Natalia, Palmer, Gene A, Mett, Vadim, Yusibov, Vidadi

“…Abstract Influenza is a globally important respiratory pathogen that causes a high degree of morbidity and mortality annually. Although current vaccines are…”
Get full text