Search Results - "Mett, Igor L"

Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally by Varfolomeev, Eugene E, Schuchmann, Marcus, Luria, Victor, Chiannilkulchai, Nuchanard, Beckmann, Jacques S, Mett, Igor L, Rebrikov, Denis, Brodianski, Vadim M, Kemper, Oliver C, Kollet, Orit, Lapidot, Tsvee, Soffer, Dror, Sobe, Tama, Avraham, Karen B, Goncharov, Tanya, Holtmann, Helmut, Lonai, Peter, Wallach, David

“…Homozygous targeted disruption of the mouse Caspase 8 ( Casp8) gene was found to be lethal in utero. The Caspase 8 null embryos exhibited impaired heart muscle…”
Get full text

A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain (∗) by Boldin, Mark P., Varfolomeev, Eugene E., Pancer, Zeev, Mett, Igor L., Camonis, Jacques H., Wallach, David

“…Signaling for cell death by Fas/APO1 occurs via a distinct region in its intracellular domain. This region contains a conserved sequence motif, the death…”
Get full text

Self-association of the “Death Domains” of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects (∗) by Boldin, Mark P., Mett, Igor L., Varfolomeev, Eugene E., Chumakov, Irina, Shemer-Avni, Yonat, Camonis, Jacques H., Wallach, David

“…Signaling by the p55 tumor necrosis factor (TNF) receptor and by the structurally related receptor Fas/APO1 is initiated by receptor clustering. Data presented…”
Get full text

The yeast two-hybrid screening technique and its use in the study of protein-protein interactions in apoptosis by Wallach, David, Boldin, Mark P, Kovalenko, Andrei V, Malinin, Nikolai L, Mett, Igor L, Camonis, Jacques H

“…The yeast two-hybrid technique provides a general approach for cloning cDNAs merely by exploiting the ability of their encoded proteins to bind to a protein of…”
Get full text

A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its ‘death domain’ by Boldin, Mark P., Mett, Igor L., Wallach, David

“…A novel protein that binds specifically to the intracellular domain of the p55 tumor necrosis factor (TNF) receptor was cloned by two-hybrid screening of a…”
Get full text