Search Results - "Metjian, Ara"

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura by Scully, Marie, Cataland, Spero R, Peyvandi, Flora, Coppo, Paul, Knöbl, Paul, Kremer Hovinga, Johanna A, Metjian, Ara, de la Rubia, Javier, Pavenski, Katerina, Callewaert, Filip, Biswas, Debjit, De Winter, Hilde, Zeldin, Robert K

“…Among patients with thrombotic thrombocytopenic purpura, the addition of caplacizumab, an anti–von Willebrand factor humanized, bivalent variable-domain-only…”
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Caplacizumab in adult patients with acquired thrombotic thrombocytopenic purpura by Hanlon, Ashley, Metjian, Ara

“…Thrombotic thrombocytopenic purpura (TTP) is usually a fatal disease caused by a deficiency of the metalloproteinase, ADAMTS13, often due to autoimmunity. This…”
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rVWF: treatment finally reaches the modern age by Metjian, Ara D.

“…In this issue of Blood, Gill et al describe the results of the first phase 3 clinical trial evaluating recombinant von Willebrand factor (rVWF) for the…”
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Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis by Peyvandi, Flora, Cataland, Spero, Scully, Marie, Coppo, Paul, Knoebl, Paul, Kremer Hovinga, Johanna A., Metjian, Ara, de la Rubia, Javier, Pavenski, Katerina, Minkue Mi Edou, Jessica, De Winter, Hilde, Callewaert, Filip

“…The efficacy and safety of caplacizumab in individuals with acquired thrombotic thrombocytopenic purpura (aTTP) have been established in the phase 2 TITAN and…”
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Use of a Thrombopoietin Mimetic for Chronic Immune Thrombocytopenic Purpura in Pregnancy by Patil, Avinash S., Dotters-Katz, Sarah K., Metjian, Ara D., James, Andra H., Swamy, Geeta K.

“…BACKGROUND:Romiplostim, a thrombopoietin mimetic, is a novel therapeutic option for patients with chronic immune thrombocytopenic purpura. We report on the…”
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Validation of the high-dose heparin confirmatory step for the diagnosis of heparin-induced thrombocytopenia by Whitlatch, Nicole L., Kong, David F., Metjian, Ara D., Arepally, Gowthami M., Ortel, Thomas L.

“…The diagnosis of heparin-induced thrombocytopenia (HIT) requires detection of antibodies to the heparin/platelet factor 4 (PF4) complexes via enzyme-linked…”
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iTTP: more long-term consequences by Metjian, Ara

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THE ROLE OF ADAMTS13 ACTIVITY LEVELS ON DISEASE EXACERBATION OR RELAPSE IN PATIENTS WITH IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA: POST HOC ANALYSIS OF THE PHASE 3 HERCULES AND POST-HERCULES STUDIES by Johanna KREMER HOVINGA, Javier DE LA RUBIA, Katerina PAVENSKI, Ara METJIAN, Paul KNÖBL, Flora PEYVANDI, Spero CATALAND, Paul COPPO, Umer KHAN, Laurel A. MENAPACE, Ana PAULA MARQUES, Sriya GUNAWARDENA, Marie SCULLY

“…Objective: The management of exacerbations and disease relapse is important for patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP)…”
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Human Leukocyte Antigen Sensitization in Solid Organ Transplantation: A Primer on Terminology, Testing, and Clinical Significance for the Apheresis Practitioner by Abbes, Sarah, Metjian, Ara, Gray, Alice, Martinu, Tereza, Snyder, Laurie, Chen, Dong‐feng, Ellis, Matthew, Arepally, Gowthami M., Onwuemene, Oluwatoyosi

“…The human leukocyte antigen (HLA) system is an important immunologic barrier that must be considered for successful solid organ transplantation. Formation of…”
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LONG-TERM OUTCOMES OF PATIENTS TREATED WITH CAPLACIZUMAB FOR IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA (ITTP): THE POST-HERCULES STUDY by Özgür Pektaş, Marie Scully, Javier de la Rubia, Katerina Pavenski, Ara Metjian, Paul Knöbl, Flora Peyvandi, Spero Cataland, Paul Coppo, Johanna A. Kremer Hovinga, Jessica Minkue Mi Edou, Rui de Passos Sousa, Sriya Gunawardena, Julie Lin

“…Objective: The efficacy and safety of caplacizumab (CPLZ) for patients (pts) with immune-mediated thrombotic thrombocytopenic purpura (iTTP; also known as…”
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INTEGRATED EFFICACY RESULTS FROM THE PHASE 2 AND PHASE 3 STUDIES WITH CAPLACIZUMAB IN PATIENTS WITH ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA by Flora Peyvandi, Spero Cataland, Marie Scully, Paul Coppo, Paul Knoebl, Johanna A. Kremer Hovinga, Ara Metjian, Javier de la Rubia, Katerina Pavenski, Jessica Minkue Mi Edou, Filip Callewaert, Hilde De Winter

“…Objective: An integrated analysis based on the Phase 2 TITAN (NCT01151423) and Phase 3 HERCULES (NCT02553317) studies with caplacizumab (CPLZ) in acquired…”
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Indications for and outcomes of therapeutic plasma exchange after cardiac transplantation: A single center retrospective study by Onwuemene, Oluwatoyosi A., Grambow, Steven C., Patel, Chetan B., Mentz, Robert J., Milano, Carmelo A., Rogers, Joseph G., Metjian, Ara D., Arepally, Gowthami M., Ortel, Thomas L.

“…Introduction Limited data are available describing indications for and outcomes of therapeutic plasma exchange (TPE) in cardiac transplantation. Methods In a…”
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Waldenström Macroglobulinemia in Hepatitis C: Case Report and Review of the Current Literature by Metjian, Ara, Pishko, Allyson, Mitchell, Aaron, Nipp, Ryan

“…Recent literature has associated hepatitis C virus with the development of non-Hodgkin lymphoma. Hepatitis C virus infection appears to promote…”
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Cytoskeletal Reorganization by G Protein-Coupled Receptors Is Dependent on Phosphoinositide 3-Kinase γ, a Rac Guanosine Exchange Factor, and Rac by Ma, Alice D., Metjian, Ara, Bagrodia, Shubha, Taylor, Stephen, Abrams, Charles S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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New advances in the treatment of adult chronic immune thrombocytopenic purpura : role of thrombopoietin receptor-stimulating agents by Metjian, Ara, Abrams, Charles S

“…Notes that decades of basic science and clinical research have led to an increased understanding of the pathophysiology of immune thrombocytopenic purpura…”
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FAST4TMA - Rapid Hospital-Based and out-Patient ADAMTS13 Testing by Martin, Clare, Metjian, Ara, Lewis, Bradley, Stromsness, Bjorn, Ero, Mike

“…Introduction: Immune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy caused by the severe deficiency of ADAMTS13 (…”
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A rare CALR variant mutation and a review of CALR in essential thrombocythemia by Diep, Robert, Metjian, Ara

“…Essential thrombocythemia (ET) is an indolent myeloproliferative neoplasm characterized by megakaryocyte hyperplasia, thrombocytosis, thrombotic and…”
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Adjuvant low-dose rituximab and plasma exchange for acquired TTP by Zwicker, Jeffrey I., Muia, Joshua, Dolatshahi, Leili, Westfield, Lisa A., Nieters, Patricia, Rodrigues, Anita, Hamdan, Ayad, Antun, Ana G., Metjian, Ara, Sadler, J. Evan

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Efficacy and safety of open‐label caplacizumab in patients with exacerbations of acquired thrombotic thrombocytopenic purpura in the HERCULES study by Knoebl, Paul, Cataland, Spero, Peyvandi, Flora, Coppo, Paul, Scully, Marie, Kremer Hovinga, Johanna A., Metjian, Ara, Rubia, Javier, Pavenski, Katerina, Minkue Mi Edou, Jessica, De Winter, Hilde, Callewaert, Filip

“…Background Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life‐threatening autoimmune thrombotic microangiopathy. Caplacizumab, an anti‐von…”
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Novel therapeutic approaches for thrombotic thrombocytopenic purpura by Tanhehco, Yvette C, Arepally, Gowthami, Metjian, Ara

“…PURPOSE OF REVIEWAcquired thrombotic thrombocytopenic purpura is an immune-mediated thrombotic microangiopathy caused by antibodies to ADAMTS13 (A Disintegrin…”
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