Search Results - "Metelitsa, L."

Expression of CD1d by myelomonocytic leukemias provides a target for cytotoxic NKT cells by METELITSA, L. S, WEINBERG, K. I, EMANUEL, P. D, SEEGER, R. C

“…Natural killer T (NKT) cells with an invariant T-cell receptor for alpha-galactosylceramide (alphaGalCer) that is presented by CD1d have been reported to be…”
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Increase of Ceramide and Induction of Mixed Apoptosis/Necrosis by N-(4-Hydroxyphenyl)- retinamide in Neuroblastoma Cell Lines by Maurer, Barry J., Metelitsa, Leonid S., Seeger, Robert C., Cabot, Myles C., Reynolds, C. Patrick

“…BACKGROUND: The synthetic retinoid N-(4-hydroxyphenyl)retinamide (4-HPR or fenretinide) is toxic to myeloid leukemia and cervical carcinoma cell lines,…”
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Human NKT Cells Mediate Antitumor Cytotoxicity Directly by Recognizing Target Cell CD1d with Bound Ligand or Indirectly by Producing IL-2 to Activate NK Cells by Metelitsa, Leonid S, Naidenko, Olga V, Kant, Anita, Wu, Hong-Wei, Loza, Matthew J, Perussia, Bice, Kronenberg, Mitchell, Seeger, Robert C

“…alpha-Galactosylceramide (alphaGalCer) stimulates NKT cells and has antitumor activity in mice. Murine NKT cells may directly kill tumor cells and induce NK…”
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Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2 by Metelitsa, Leonid S, Wu, Hong-Wei, Wang, Hong, Yang, Yujun, Warsi, Zamir, Asgharzadeh, Shahab, Groshen, Susan, Wilson, S Brian, Seeger, Robert C

“…CD1d-restricted Valpha24-Jalpha18-invariant natural killer T cells (iNKTs) are potentially important in tumor immunity. However, little is known about their…”
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Flow cytometry for natural killer T cells: multi-parameter methods for multifunctional cells by Metelitsa, Leonid S

“…Vα24-Jα18 invariant natural killer T cells (iNKT) are an evolutionary conserved sub-lineage of T cells with effector-memory phenotype that often express an NK…”
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NKT and T cells: coordinate regulation of NK‐like phenotype and cytokine production by Loza, Matthew J., Metelitsa, Leonid S., Perussia, Bice

“…A maturation‐dependent change in phenotype and cytokine production from relatively immature CD161– or CD161+, IL‐13+IL‐4+, IFN‐γ–, to mature CD161+CD56+ IFN‐γ+…”
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SPECIFICITIES OF THE SUBSET PROFILE OF PERIPHERAL BLOOD IN PATIENTS WITH GLIOBLASTOMA: PATHOGENETIC AND CLINICAL ASSESSMENTS by Chumakov, V. A., Pronina, O. A., Kachkov, I. A., Korshounov, A. G., Pineguin, B. V., Anan’eva, I. I., Elbeik, T., Metelitsa, L. S., Dorofeev, A. E., Gnouchev, N. V., Souchkov, S. V.

“…In glioblastoma (GB), it is necessary to take into consideration GB-associated secondary immunodeficiency (SID), so-called syndrome of tumor-associated SID…”
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Research on sensitivity of biomodels for initial testing potential physiologically active substances by the method of cluster analysis by Semeniuta, I. V., Metelitsa, L. A., Kalashnikova, L. E., Prokopenko, R. A.

“…The sensitivity of blood cells and functional activity of unstriped muscles to physiologically active substances of various chemical nature has been…”
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Long term follow up of subsequent malignancies in patients treated with genetically modified immune effectors by Muhsen, I.N., Steffin, D., Ahmed, N., Hegde, M., Dakhova, O., Wang, T., Wu, M., Gottschalk, S., Whittle, S., Lulla, P., Mamonkin, M., Omer, B., Rouce, R.H., Heczey, A., Metelitsa, L., Hill, L., Ramos, C.A., Rooney, C., Brenner, M., Heslop, H.

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AUTOIMMUNE MYOCARDITIS: PERIPHERAL BLOOD ARCHITECTONICS AND CLINICAL COURSE FEATURES by Z. S. Shogenov, K. A. Akhmedilova, N. N. Kekenadze, M. M. Agirov, O. A. Pronina, B. V. Pinegin, T. Elbeik, L. S. Metelitsa, S. B. Suchkov, P. Kh. Dzhanashiya

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Synthesis of N-(phosphonomethyl)glycine derivatives and studies of their immunotropic activity by Shevchuk, M. V., Metelitsa, L. A., Charochkina, L. L., Mogilevich, S. E., Rusanov, E. B., Sorochinsky, A. E., Khilya, V. P., Romanenko, V. D., Kukhar, V. P.

“…The Petasis reaction between glyoxylic acid, α-amino phosphonates, and organylboronic acid afforded N -phosphonomethyl-α-amino acids. This method has an…”
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Ganglioside GM2/GD2 Synthetase mRNA Is a Marker for Detection of Infrequent Neuroblastoma Cells in Bone Marrow by Hoon, Dave S.B., Kuo, Christine T., Wen, Shenghua, Wang, Hong, Metelitsa, Leonid, Reynolds, C. Patrick, Seeger, Robert C.

“…GalNAcβ1-4(NeuAcα2-3)Galβ1-4Glcβ1-Cer (GM2)/GalNAcβ1-4(NeuAcα2-8NeuAcα2-3)Galβ1-4Glcβ1-1Cer (GD2) synthetase [β-1,4- N-acetyl-galactosaminyl transferase…”
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Integrins alpha(v)beta3 and alpha(v)beta5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide by Erdreich-Epstein, A, Shimada, H, Groshen, S, Liu, M, Metelitsa, L S, Kim, K S, Stins, M F, Seeger, R C, Durden, D L

“…Inhibition of the RGD-binding integrins, alpha(v)beta3 and alpha(v)beta5, prevents endothelial cell anchorage and induces endothelial apoptosis, which results…”
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Integrins αvβ3 and αvβ5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide by ERDREICH-EPSTEIN, A, SHIMADA, H, GROSHEN, S, MING LIU, METELITSA, L. S, KWANG SIK KIM, STINS, M. F, SEEGER, R. C, DURDEN, D. L

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Antidisialoganglioside/granulocyte macrophage–colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcγRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis by Metelitsa, Leonid S., Gillies, Stephen D., Super, Michael, Shimada, Hiroyuki, Reynolds, C. Patrick, Seeger, Robert C.

“…Polymorphonuclear leukocytes (PMNs) mediate antibody-dependent cellular cytotoxicity (ADCC), which is increased by the addition of granulocyte-macrophage…”
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Regulation of the phagocyte activity of polymorphonuclear leukocytes by several medical agents by Metelitsa, L A, Mogilevich, S E, Luĭk, A I

“…Effects of some drugs on different levels of phagocytic activity of polymorphonuclear leukocytes (PMNL) of human peripheral blood were studied in vitro. The…”
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Effects of drugs on the results of passive hemagglutination test by Metelitsa, L A, Mogilevich, S E, Luĭk, A I

“…Study on the effects of some drugs on the results of passive hemagglutination test used for the detection of antitetanus antibodies in the blood serum showed…”
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Application of topological indexes to predict immunomodulating activity of new peptides by Kholodovich, V. V., Tanchuk, V. Yu, Kovalishin, V. V., Tetko, I. V., Poyarkova, S. A., Metelitsa, L. A., Luik, A. I.

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Immunomodulating effect of berlithione in clean-up workers of the Chernobyl nuclear plant accident by Zueva, N A, Metelitsa, L A, Kovalenko, A N, Efimov, A S

“…Effects of the antioxidant berlithione (alpha-lipoic acid) on indices for the immune system, such as complement titer, C3-component of the complement, reaction…”
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Use of parameters of E-rosette formation and electrophoretic mobility for comprehensive evaluation of the functional state of leukocytes by Metelitsa, L A, Kalashnikova, L E, Mogilevich, S A, Luĭk, A I

“…The influence of some drugs on E-rosette formation by lymphocytes and on electrophoretic mobility of neutrophilic leukocytes has been studied. It has been…”
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