Search Results - "Metcalfe, J. C"

Isolation of Gene Markers of Differentiated and Proliferating Vascular Smooth Muscle Cells by Shanahan, Catherine M, Weissberg, Peter L, Metcalfe, James C

“…To isolate specific markers of both differentiated and proliferating vascular smooth muscle cells (VSMCs), we used the technique of differential cDNA screening…”
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The complex polyploid genome architecture of sugarcane by Healey, A. L., Garsmeur, O., Lovell, J. T., Shengquiang, S., Sreedasyam, A., Jenkins, J., Plott, C. B., Piperidis, N., Pompidor, N., Llaca, V., Metcalfe, C. J., Doležel, J., Cápal, P., Carlson, J. W., Hoarau, J. Y., Hervouet, C., Zini, C., Dievart, A., Lipzen, A., Williams, M., Boston, L. B., Webber, J., Keymanesh, K., Tejomurthula, S., Rajasekar, S., Suchecki, R., Furtado, A., May, G., Parakkal, P., Simmons, B. A., Barry, K., Henry, R. J., Grimwood, J., Aitken, K. S., Schmutz, J., D’Hont, A.

“…Sugarcane, the world’s most harvested crop by tonnage, has shaped global history, trade and geopolitics, and is currently responsible for 80% of sugar…”
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High expression of genes for calcification-regulating proteins in human atherosclerotic plaques by Shanahan, C M, Cary, N R, Metcalfe, J C, Weissberg, P L

“…Calcification is common in atheromatous plaques and may contribute to plaque rupture and subsequent thrombosis. However, little is known about the mechanisms…”
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Centromere Dynamics and Chromosome Evolution in Marsupials by O'Neill, R. J., Eldridge, M. D. B., Metcalfe, C. J.

“…The eukaryotic centromere poses an interesting evolutionary paradox: it is a chromatin entity indispensable to precise chromosome segregation in all…”
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Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice by Grainger, David J, Kemp, Paul R, Liu, Alexander C, Lawn, Richard M, Metcalfe, James C

“…A HIGH concentration of serum lipoprotein(a) is a risk factor for atherosclerosis. Lipoprotein(a) consists of low-density lipoprotein with the additional…”
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Combretastatin-A4 disrupts neovascular development in non-neoplastic tissue by GRIGGS, J, HESKETH, R, SMITH, G. A, BRINDLE, K. M, METCALFE, J. C, THOMAS, G. A, WILLIAMS, E. D

“…Combretastatin-A4 phosphate (cis-CA-4) is a tubulin-binding agent currently undergoing clinical trials as an anti-tumour drug. We have investigated whether…”
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Molecular evidence of symbiotic activity between Symbiodinium and Tridacna maxima larvae by Mies, Miguel, Van Sluys, M. A., Metcalfe, C. J., Sumida, P. Y. G.

“…Dinoflagellates in the genus Symbiodinium (zooxanthellae) provide the photosynthesis that sustains the majority of primary production in coral reefs. They…”
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Mechanisms of pHi Recovery After Global Ischemia in the Perfused Heart by Vandenberg, Jamie I, Metcalfe, James C, Grace, Andrew A

“…A Na -HCO3 coinflux carrier and the Na -H antiport have both been shown to contribute to recovery from intracellular acidosis in cardiac tissue. We have…”
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Proliferation of Human Smooth Muscle Cells Promoted by Lipoprotein(a) by Grainger, David J., Kirschenlohr, Heide L., Metcalfe, James C., Weissberg, Peter L., Wade, David P., Lawn, Richard M.

“…Elevated blood concentrations of lipoprotein(a) [Lp(a)] and its constituent, apolipoprotein(a) [apo(a)], constitute a major risk factor for atherosclerosis,…”
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Tamoxifen: Teaching an old drug new tricks? by Grainger, David J, Metcalfe, James C

“…Tamoxifen is the most widely studied member of a class of molecules called the triphenylethylenes (TPEs). These molecules were developed by successive chemical…”
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Nov Gene Encodes Adhesion Factor for Vascular Smooth Muscle Cells and Is Dynamically Regulated in Response to Vascular Injury by Ellis, Peter D, Chen, Qin, Barker, Patrick J, Metcalfe, James C, Kemp, Paul R

“…Nephroblastoma overexpressed (NOV) is a member of the CCN family (connective tissue growth factor, CYR61, and NOV) of proteins that are involved in regulating…”
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Tamoxifen decreases cholesterol sevenfold and abolishes lipid lesion development in apolipoprotein E knockout mice by RECKLESS, J, METCALFE, J. C, GRAINGER, D. J

“…Apolipoprotein E (apo E) knockout mice develop severe vascular lipid lesions resembling human atherosclerotic plaques, irrespective of the fat content of their…”
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No Effect of 60 Hz Electromagnetic Fields on MYC or β-Actin Expression in Human Leukemic Cells by Lacy-Hulbert, Adam, Wilkins, Roger C., Hesketh, T. Robin, Metcalfe, James C.

“…Epidemiological studies have shown weak correlations between exposure to extremely low-frequency electromagnetic fields (ELF EMFs) and the incidence of several…”
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Increased PAI activity and PAI-1 antigen occurring with an oral fat load: associations with PAI-1 genotype and plasma active TGF- β levels by Byrne, C.D, Wareham, N.J, Martensz, N.D, Humphries, S.E, Metcalfe, J.C, Grainger, D.J

“…Whether the post-prandial lipemic response is linked to potentially pro-atherogenic and/or prothrombotic changes in plasminogen activator inhibitor (PAI) and…”
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Monocyte chemoattractant protein-1 but not tumor necrosis factor-α is correlated with monocyte infiltration in mouse lipid lesions by RECKLESS, J, RUBIN, E. M, VERSTUYFT, J. B, METCALFE, J. C, GRAINGER, D. J

“…Apolipoprotein (apo)(a) transgenic mice and C57BL/6 mice fed a high fat diet develop similar-sized lipid lesions, but lesions in apo(a) mice are devoid of…”
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A Transforming Growth Factor beta 1 Signal Peptide Variant Increases Secretion in Vitro and Is Associated with Increased Incidence of Invasive Breast Cancer by Dunning, A M, Ellis, P D, McBride, S, Kirschenlohr, H L, Healey, C S, Kemp, PR, Luben, R N, Chang-Claude, J, Mannermaa, A, Kataja, V, Pharoah, PDP, Easton, D F, Ponder, BAJ, Metcalfe, J C

“…There is evidence that transforming growth factor (TGF) beta acts as a suppressor of tumor initiation but also as a promoter of tumor progression when the…”
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Genetic control of the circulating concentration of transforming growth factor type beta 1 by Grainger, D J, Heathcote, K, Chiano, M, Snieder, H, Kemp, PR, Metcalfe, J C, Carter, N D, Spector, T D

“…The concentration of transforming growth factor beta (TGF- beta ) in plasma has been correlated with the development of several diseases, including…”
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The mechanism of the calcium signal and correlation with histamine release in 2H3 cells by Beaven, M A, Rogers, J, Moore, J P, Hesketh, T R, Smith, G A, Metcalfe, J C

“…Rat basophil leukemic (2H3) cells ( Siraganian , R.P., McGivney , A., Barsumian , E. L., Crews, F. T., Hirata , F., and Axelrod , J. (1982) Fed. Proc. 41,…”
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Biological responses to electromagnetic fields by Lacy-Hulbert, A, Metcalfe, J C, Hesketh, R

“…Electrification in developed countries has progressively increased the mean level of extremely low-frequency electromagnetic fields (ELF-EMFs) to which…”
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Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes by Hesketh, T R, Smith, G A, Moore, J P, Taylor, M V, Metcalfe, J C

“…The effects of the lectins concanavalin A, succinylated concanavalin A, and wheat germ agglutinin on the free cytoplasmic Ca2+ concentration in mouse…”
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