Search Results - "Metcalf, Julia"

Interleukin-15 (IL-15) Strongly Correlates with Increasing HIV-1 Viremia and Markers of Inflammation by Swaminathan, Sanjay, Qiu, Ju, Rupert, Adam W, Hu, Zonghui, Higgins, Jeanette, Dewar, Robin L, Stevens, Randy, Rehm, Catherine A, Metcalf, Julia A, Sherman, Brad T, Baseler, Michael W, Lane, H Clifford, Imamichi, Tomozumi

“…IL-15 has been postulated to play an important role in HIV-1 infection, yet there are conflicting reports regarding its expression levels in these patients. We…”
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Pre-ART levels of inflammation and coagulation markers are strong predictors of death in a South African cohort with advanced HIV disease by Ledwaba, Lotty, Tavel, Jorge A, Khabo, Paul, Maja, Patrick, Qin, Jing, Sangweni, Phumele, Liu, Xiao, Follmann, Dean, Metcalf, Julia A, Orsega, Susan, Baseler, Beth, Neaton, James D, Lane, H Clifford

“…Levels of high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), and D-dimer predict mortality in HIV patients on antiretroviral therapy (ART) with…”
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ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia by Maldarelli, Frank, Palmer, Sarah, King, Martin S, Wiegand, Ann, Polis, Michael A, Mican, JoAnn, Kovacs, Joseph A, Davey, Richard T, Rock-Kress, Diane, Dewar, Robin, Liu, Shuying, Metcalf, Julia A, Rehm, Catherine, Brun, Scott C, Hanna, George J, Kempf, Dale J, Coffin, John M, Mellors, John W

“…Current antiretroviral therapy is effective in suppressing but not eliminating HIV-1 infection. Understanding the source of viral persistence is essential for…”
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HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion by Maldarelli, Frank, Kearney, Mary, Palmer, Sarah, Stephens, Robert, Mican, JoAnn, Polis, Michael A, Davey, Richard T, Kovacs, Joseph, Shao, Wei, Rock-Kress, Diane, Metcalf, Julia A, Rehm, Catherine, Greer, Sarah E, Lucey, Daniel L, Danley, Kristen, Alter, Harvey, Mellors, John W, Coffin, John M

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The benefit of immediate compared with deferred antiretroviral therapy on CD4+ cell count recovery in early HIV infection by Sharma, Shweta, Schlusser, Katherine E, de la Torre, Pola, Tambussi, Giuseppe, Draenert, Rika, Pinto, Angie N, Metcalf, Julia A, Neaton, James D, Laeyendecker, Oliver

“…OBJECTIVE:To assess the impact of immediate vs. deferred antiretroviral therapy (ART) on CD4 recovery among individuals early in HIV infection. DESIGN:Using…”
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The association between serum biomarkers and disease outcome in influenza A(H1N1)pdm09 virus infection: results of two international observational cohort studies by Davey, Jr, Richard T, Lynfield, Ruth, Dwyer, Dominic E, Losso, Marcello H, Cozzi-Lepri, Alessandro, Wentworth, Deborah, Lane, H Clifford, Dewar, Robin, Rupert, Adam, Metcalf, Julia A, Pett, Sarah L, Uyeki, Timothy M, Bruguera, Jose Maria, Angus, Brian, Cummins, Nathan, Lundgren, Jens, Neaton, James D

“…Prospective studies establishing the temporal relationship between the degree of inflammation and human influenza disease progression are scarce. To assess…”
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Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy by Migueles, Stephen A, Weeks, Kristin A, Nou, Eric, Berkley, Amy M, Rood, Julia E, Osborne, Christine M, Hallahan, Claire W, Cogliano-Shutta, Nancy A, Metcalf, Julia A, McLaughlin, Mary, Kwan, Richard, Mican, JoAnn M, Davey, Jr, Richard T, Connors, Mark

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Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors by Zonios, Dimitrios I., Falloon, Judith, Bennett, John E., Shaw, Pamela A., Chaitt, Doreen, Baseler, Michael W., Adelsberger, Joseph W., Metcalf, Julia A., Polis, Michael A., Kovacs, Stephen J., Kovacs, Joseph A., Davey, Richard T., Lane, H. Clifford, Masur, Henry, Sereti, Irini

“…Idiopathic CD4+ lymphocytopenia (ICL) is a rare non–HIV-related syndrome with unclear natural history and prognosis. This prospective natural history cohort…”
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The effects of storage temperature on PBMC gene expression by Yang, Jun, Diaz, Norma, Adelsberger, Joseph, Zhou, Xueyuan, Stevens, Randy, Rupert, Adam, Metcalf, Julia A, Baseler, Mike, Barbon, Christine, Imamichi, Tomozumi, Lempicki, Richard, Cosentino, Louis M

“…Cryopreservation of peripheral blood mononuclear cells (PBMCs) is a common and essential practice in conducting research. There are different reports in the…”
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Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-Experienced Patients Are Missed by Standard Genotype Analysis by PALMER, Sarah, KEARNEY, Mary, METCALF, Julia A, HAMMER, Scott, MELLORS, John W, COFFIN, John M, MALDARELLI, Frank, HALVAS, Elias K, BIXBY, Christian J, BAZMI, Holly, ROCK, Diane, FALLOON, Judith, DAVEY, Richard T, DEWAR, Robin L

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New Real-Time Reverse Transcriptase-Initiated PCR Assay with Single-Copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in Plasma by PALMER, Sarah, WIEGAND, Ann P, MELLORS, John W, COFFIN, John M, MALDARELLI, Frank, BAZMI, Holly, MICAN, Joann M, POLIS, Michael, DEWAR, Robin L, PLANTA, Angeline, SHUYING LIU, METCALF, Julia A

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Plasma interleukin-27 (IL-27) levels are not modulated in patients with chronic HIV-1 infection by Swaminathan, Sanjay, Hu, Zonghui, Rupert, Adam W, Higgins, Jeanette M, Dewar, Robin L, Stevens, Randy, Chen, Qian, Rehm, Catherine A, Metcalf, Julia A, Baseler, Michael W, Lane, H Clifford, Imamichi, Tomozumi

“…IL-27 is an immunomodulatory cytokine with potent anti-HIV properties in PBMCs, CD4+ T cells, macrophages and immature dendritic cells. Previous smaller…”
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Systemic Inflammation, Coagulation, and Clinical Risk in the START Trial by Baker, Jason V, Sharma, Shweta, Grund, Birgit, Rupert, Adam, Metcalf, Julia A, Schechter, Mauro, Munderi, Paula, Aho, Inka, Emery, Sean, Babiker, Abdel, Phillips, Andrew, Lundgren, Jens D, Neaton, James D, Lane, H Clifford

“…Abstract Background The Strategic Timing of AntiRetroviral Treatment (START) trial demonstrated that immediate (at CD4+ >500 cells/µL) vs deferred (to CD4+…”
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Influence of sample collection tube method, anticoagulant-containing plasma versus serum, on influenza virus hemagglutination inhibition titer and microneutralization titer serological assays by Morrison, Brian J, Martin, Nicholas J, Rehman, Tauseef, Ewing, Dan, Dewar, Robin L, Metcalf, Julia, Sun, Peifang, Beigel, John, Luke, Thomas C, Raviprakash, Kanakatte

“…The hemagglutination-inhibition (HAI) assay is a critical component for measurement of immunogenicity in influenza vaccine development. It is unknown if the…”
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Comparison of Self-report to Biomarkers of Recent HIV Infection: Findings from the START Trial by Schlusser, Katherine E., Sharma, Shweta, de la Torre, Pola, Tambussi, Giuseppe, Draenert, Rika, Pinto, Angie N., Metcalf, Julia A., German, Danielle, Neaton, James D., Laeyendecker, Oliver

“…Identifying individuals with recent HIV infection is critical to research related to viral reservoirs, outbreak investigations and intervention applications. A…”
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Human Immunodeficiency Virus Viremia Induces Plasmacytoid Dendritic Cell Activation In Vivo and Diminished Alpha Interferon Production In Vitro by TILTON, John C, MANION, Maura M, LIFSON, Jeffrey D, METCALF, Julia A, LEMPICKI, Richard A, CONNORS, Mark, LUSKIN, Marlise R, JOHNSON, Alison J, PATAMAWENU, Andy A, HALLAHAN, Claire W, COGLIANO-SHUTTA, Nancy A, MICAN, Joann M, DAVEY, Richard T, KOTTILIL, Shyam

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HIV-1 infected monozygotic twins: a tale of two outcomes by Tazi, Loubna, Imamichi, Hiromi, Hirschfeld, Steven, Metcalf, Julia A, Orsega, Susan, Pérez-Losada, Marcos, Posada, David, Lane, H Clifford, Crandall, Keith A

“…Replicate experiments are often difficult to find in evolutionary biology, as this field is inherently an historical science. However, viruses, bacteria and…”
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Tuberculosis risk factors and mortality for HIV-infected persons receiving antiretroviral therapy in South Africa by KOMATI, Stephanus, SHAW, Pamela A, STUBBS, Nomso, MATHIBEDI, Monkwe J, MALAN, Lizette, SANGWENI, Phumelele, METCALF, Julia A, MASUR, Henry, HASSIM, Shaheen

“…To determine important risk factors for and impact of tuberculosis on survival in HIV-infected patients starting antiretroviral therapy (ART) in South Africa…”
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Changes in Paracrine Interleukin-2 Requirement, CCR7 Expression, Frequency, and Cytokine Secretion of Human Immunodeficiency Virus-Specific CD4+ T Cells Are a Consequence of Antigen Load by TILTON, John C, LUSKIN, Marlise R, JOHNSON, Alison J, MANION, Maura, HALLAHAN, Claire W, METCALF, Julia A, MCLAUGHLIN, Mary, DAVEY, Richard T, CONNORS, Mark

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Detection of a Substantial Rate of Multidrug-Resistant Tuberculosis in an HIV-Infected Population in South Africa by Active Monitoring of Sputum Samples by Hassim, Shaheen, Shaw, Pamela A., Sangweni, Phumelele, Malan, Lizette, Ntshani, Ella, Mathibedi, Monkwe Jethro, Stubbs, Nomso, Metcalf, Julia A., Eckes, Risa, Masur, Henry, Komati, Stephanus

“…Background Tuberculosis (TB) coinfection with human immunodeficiency virus (HIV) is a substantial problem in South Africa. There has been a presumption that…”
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