Search Results - "Metallomics"

Cadmium in plants: uptake, toxicity, and its interactions with selenium fertilizers by Ismael, Marwa A, Elyamine, Ali Mohamed, Moussa, Mohamed G, Cai, Miaomiao, Zhao, Xiaohu, Hu, Chengxiao

“…Cd is the third major contaminant of greatest hazard to the environment after mercury and lead and is considered as the only metal that poses health risks to…”
Get full text

Targeting copper in cancer therapy: 'Copper That Cancer' by Denoyer, Delphine, Masaldan, Shashank, La Fontaine, Sharon, Cater, Michael A

“…Copper is an essential micronutrient involved in fundamental life processes that are conserved throughout all forms of life. The ability of copper to catalyze…”
Get full text

Mechanistic evaluation of translocation and physiological impact of titanium dioxide and zinc oxide nanoparticles on the tomato (Solanum lycopersicum L.) plant by Raliya, Ramesh, Nair, Remya, Chavalmane, Sanmathi, Wang, Wei-Ning, Biswas, Pratim

“…Sustainable use of nanotechnology for agricultural practice requires an understanding of the plant's life cycle and potential toxicological impacts of…”
Get full text

The elemental role of iron in DNA synthesis and repair by Puig, Sergi, Ramos-Alonso, Lucía, Romero, Antonia María, Martínez-Pastor, María Teresa

“…Iron is an essential redox element that functions as a cofactor in many metabolic pathways. Critical enzymes in DNA metabolism, including multiple DNA repair…”
Get full text

Iron homeostasis in plants - a brief overview by Connorton, James M, Balk, Janneke, Rodríguez-Celma, Jorge

“…Iron plays a crucial role in biochemistry and is an essential micronutrient for plants and humans alike. Although plentiful in the Earth's crust it is not…”
Get full text

Antibacterial mechanism of silver nanoparticles in Pseudomonas aeruginosa: proteomics approach by Yan, Xueting, He, Bin, Liu, Lihong, Qu, Guangbo, Shi, Jianbo, Hu, Ligang, Jiang, Guibin

“…Silver nanoparticles (AgNPs) are the nanomaterials most widely used as antimicrobial agents in a range of consumer products, due to the environmental release…”
Get full text

Chemistry and biology of ferritin by Plays, Marina, Müller, Sebastian, Rodriguez, Raphaël

“…Iron is an essential element required by cells and has been described as a key player in ferroptosis. Ferritin operates as a fundamental iron storage protein…”
Get full text

Selenium biochemistry and its role for human health by Roman, Marco, Jitaru, Petru, Barbante, Carlo

“…Despite its very low level in humans, selenium plays an important and unique role among the (semi)metal trace essential elements because it is the only one for…”
Get full text

The transferrin receptor: the cellular iron gate by Gammella, Elena, Buratti, Paolo, Cairo, Gaetano, Recalcati, Stefania

“…The transferrin receptor (TfR1), which mediates cellular iron uptake through clathrin-dependent endocytosis of iron-loaded transferrin, plays a key role in…”
Get full text

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells by Kell, Douglas B, Pretorius, Etheresia

“…"Serum ferritin" presents a paradox, as the iron storage protein ferritin is not synthesised in serum yet is to be found there. Serum ferritin is also a well…”
Get full text

Defining the human copper proteome and analysis of its expression variation in cancers by Blockhuys, S, Celauro, E, Hildesjö, C, Feizi, A, Stål, O, Fierro-González, J C, Wittung-Stafshede, P

“…Copper (Cu) is essential for living organisms, and acts as a cofactor in many metabolic enzymes. To avoid the toxicity of free Cu, organisms have specific…”
Get full text

Ceruloplasmin and other copper binding components of blood plasma and their functions: an update by Linder, M. C

“…We know that blood plasma contains many proteins and also other components that bind copper. The largest contributor to copper in the plasma is ceruloplasmin,…”
Get full text

Altered copper homeostasis underlies sensitivity of hepatocellular carcinoma to copper chelation by Davis, Caroline I, Gu, Xingxing, Kiefer, Ryan M, Ralle, Martina, Gade, Terence P, Brady, Donita C

“…Hepatocellular carcinoma (HCC), the most common primary liver cancer, of which ∼800 000 new cases will be diagnosed worldwide this year, portends a five-year…”
Get full text

Mechanisms of metal toxicity in plants by Küpper, Hendrik, Andresen, Elisa

“…Metal toxicity in plants is still a global problem for the environment, agriculture and ultimately human health. This review initially addresses the current…”
Get full text

First-in-class ruthenium anticancer drug (KP1339/IT-139) induces an immunogenic cell death signature in colorectal spheroids in vitro by Wernitznig, Debora, Kiakos, Konstantinos, Del Favero, Giorgia, Harrer, Nathalie, Machat, Herwig, Osswald, Annika, Jakupec, Michael A, Wernitznig, Andreas, Sommergruber, Wolfgang, Keppler, Bernhard K

“…The ruthenium complex sodium trans-[tetrachloridobis(1H-indazole)ruthenate(iii)] (KP1339/IT-139) showed preclinical activity in a variety of in vivo tumor…”
Get full text

Selenium, selenoproteins and neurodegenerative diseases by Cardoso, Bárbara Rita, Roberts, Blaine R, Bush, Ashley I, Hare, Dominic J

“…It is unsurprising that our understanding of the role of selenium in neurological function is somewhat immature, considering its relatively recent discovery as…”
Get full text

The biological fate of gadolinium-based MRI contrast agents: a call to action for bioinorganic chemists by Le Fur, Mariane, Caravan, Peter

“…Gadolinium-based contrast agents (GBCAs) are widely used with clinical magnetic resonance imaging (MRI), and 10 s of millions of doses of GBCAs are…”
Get full text

The role of vanadium in biology by Rehder, Dieter

“…Vanadium is special in at least two respects: on the one hand, the tetrahedral anion vanadate( v ) is similar to the phosphate anion; vanadate can thus…”
Get full text

Metallothionein diversity and distribution in the tree of life: a multifunctional protein by Ziller, Antoine, Fraissinet-Tachet, Laurence

“…MTs are small cysteine-rich proteins that chelate metal ions such as Cu + and Zn 2+ , and are widely distributed in several life domains, in particular the…”
Get full text

The human iron-proteome by Andreini, Claudia, Putignano, Valeria, Rosato, Antonio, Banci, Lucia

“…Organisms from all kingdoms of life use iron-proteins in a multitude of functional processes. We applied a bioinformatics approach to investigate the human…”
Get full text