Search Results - "Metabolites"

NMR Spectroscopy for Metabolomics Research by Emwas, Abdul-Hamid, Roy, Raja, McKay, Ryan T, Tenori, Leonardo, Saccenti, Edoardo, Gowda, G A Nagana, Raftery, Daniel, Alahmari, Fatimah, Jaremko, Lukasz, Jaremko, Mariusz, Wishart, David S

“…Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the three principal analytical techniques used in metabolomics (the other two…”
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MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics by Pang, Zhiqiang, Chong, Jasmine, Li, Shuzhao, Xia, Jianguo

“…Liquid chromatography coupled to high-resolution mass spectrometry platforms are increasingly employed to comprehensively measure metabolome changes in systems…”
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A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery by Anand, Uttpal, Jacobo-Herrera, Nadia, Altemimi, Ammar, Lakhssassi, Naoufal

“…The war on multidrug resistance (MDR) has resulted in the greatest loss to the world's economy. Antibiotics, the bedrock, and wonder drug of the 20th century…”
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Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics by Blaženović, Ivana, Kind, Tobias, Ji, Jian, Fiehn, Oliver

“…The annotation of small molecules remains a major challenge in untargeted mass spectrometry-based metabolomics. We here critically discuss structured…”
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Systems Biology and Multi-Omics Integration: Viewpoints from the Metabolomics Research Community by Pinu, Farhana R, Beale, David J, Paten, Amy M, Kouremenos, Konstantinos, Swarup, Sanjay, Schirra, Horst J, Wishart, David

“…The use of multiple omics techniques (i.e., genomics, transcriptomics, proteomics, and metabolomics) is becoming increasingly popular in all facets of life…”
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MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools by Ernst, Madeleine, Kang, Kyo Bin, Caraballo-Rodríguez, Andrés Mauricio, Nothias, Louis-Felix, Wandy, Joe, Chen, Christopher, Wang, Mingxun, Rogers, Simon, Medema, Marnix H, Dorrestein, Pieter C, van der Hooft, Justin J J

“…Metabolomics has started to embrace computational approaches for chemical interpretation of large data sets. Yet, metabolite annotation remains a key…”
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Glucagon-Like Peptide-1 Receptor Agonists for Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: An Updated Meta-Analysis of Randomized Controlled Trials by Mantovani, Alessandro, Petracca, Graziana, Beatrice, Giorgia, Csermely, Alessandro, Lonardo, Amedeo, Targher, Giovanni

“…To assess the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for treatment of nonalcoholic fatty liver disease (NAFLD) or steatohepatitis…”
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MetaboAnalystR 2.0: From Raw Spectra to Biological Insights by Chong, Jasmine, Yamamoto, Mai, Xia, Jianguo

“…Global metabolomics based on high-resolution liquid chromatography mass spectrometry (LC-MS) has been increasingly employed in recent large-scale multi-omics…”
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Machine Learning Applications for Mass Spectrometry-Based Metabolomics by Liebal, Ulf W, Phan, An N T, Sudhakar, Malvika, Raman, Karthik, Blank, Lars M

“…The metabolome of an organism depends on environmental factors and intracellular regulation and provides information about the physiological conditions…”
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L-Carnitine and Acylcarnitines: Mitochondrial Biomarkers for Precision Medicine by McCann, Marc R, George De la Rosa, Mery Vet, Rosania, Gus R, Stringer, Kathleen A

“…Biomarker discovery and implementation are at the forefront of the precision medicine movement. Modern advances in the field of metabolomics afford the…”
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The Effects of Plant-Associated Bacterial Exopolysaccharides on Plant Abiotic Stress Tolerance by Morcillo, Rafael, Manzanera, Maximino

“…Plant growth-promoting rhizobacteria (PGPR) are beneficial soil microorganisms that can stimulate plant growth and increase tolerance to biotic and abiotic…”
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Metabolomics in the Context of Plant Natural Products Research: From Sample Preparation to Metabolite Analysis by Salem, Mohamed A, Perez de Souza, Leonardo, Serag, Ahmed, Fernie, Alisdair R, Farag, Mohamed A, Ezzat, Shahira M, Alseekh, Saleh

“…Plant-derived natural products have long been considered a valuable source of lead compounds for drug development. Natural extracts are usually composed of…”
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Vitamin D Sources, Metabolism, and Deficiency: Available Compounds and Guidelines for Its Treatment by Dominguez, Ligia J, Farruggia, Mario, Veronese, Nicola, Barbagallo, Mario

“…Studies on vitamin/hormone D deficiency have received a vast amount of attention in recent years, particularly concerning recommendations, guidelines, and…”
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Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target by Behbodikhah, Jennifer, Ahmed, Saba, Elyasi, Ailin, Kasselman, Lora J., De Leon, Joshua, Glass, Amy D., Reiss, Allison B.

“…Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two major isoforms: apoB48 and apoB100. ApoB48 is found in…”
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CFM-ID 3.0: Significantly Improved ESI-MS/MS Prediction and Compound Identification by Djoumbou-Feunang, Yannick, Pon, Allison, Karu, Naama, Zheng, Jiamin, Li, Carin, Arndt, David, Gautam, Maheswor, Allen, Felicity, Wishart, David S

“…Metabolite identification for untargeted metabolomics is often hampered by the lack of experimentally collected reference spectra from tandem mass spectrometry…”
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Yeast Protein as an Easily Accessible Food Source by Jach, Monika Elżbieta, Serefko, Anna, Ziaja, Maria, Kieliszek, Marek

“…In recent years, the awareness and willingness of consumers to consume healthy food has grown significantly. In order to meet these needs, scientists are…”
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Antifungal Drugs by Houšť, Jiří, Spížek, Jaroslav, Havlíček, Vladimír

“…We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved…”
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Unraveling Arbuscular Mycorrhiza-Induced Changes in Plant Primary and Secondary Metabolome by Kaur, Sukhmanpreet, Suseela, Vidya

“…Arbuscular mycorrhizal fungi (AMF) is among the most ubiquitous plant mutualists that enhance plant growth and yield by facilitating the uptake of phosphorus…”
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Biostimulants for Plant Growth and Mitigation of Abiotic Stresses: A Metabolomics Perspective by Nephali, Lerato, Piater, Lizelle A, Dubery, Ian A, Patterson, Veronica, Huyser, Johan, Burgess, Karl, Tugizimana, Fidele

“…Adverse environmental conditions due to climate change, combined with declining soil fertility, threaten food security. Modern agriculture is facing a pressing…”
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Glutathione Metabolism in Plants under Stress: Beyond Reactive Oxygen Species Detoxification by Dorion, Sonia, Ouellet, Jasmine C., Rivoal, Jean

“…Glutathione is an essential metabolite for plant life best known for its role in the control of reactive oxygen species (ROS). Glutathione is also involved in…”
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