Search Results - "Meszaros, J."

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy by Adapala, R K, Thoppil, R J, Ghosh, K, Cappelli, H C, Dudley, A C, Paruchuri, S, Keshamouni, V, Klagsbrun, M, Meszaros, J G, Chilian, W M, Ingber, D E, Thodeti, C K

“…Tumor vessels are characterized by abnormal morphology and hyperpermeability that together cause inefficient delivery of chemotherapeutic agents. Although…”
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Novel noncanonical regulation of soluble VEGF/VEGFR2 signaling by mechanosensitive ion channel TRPV4 by Kanugula, Anantha K., Adapala, Ravi K., Midha, Priya, Cappelli, Holly C., Meszaros, J. Gary, Paruchuri, Sailaja, Chilian, William M., Thodeti, Charles K.

“…ABSTRACT VEGF signaling via VEGF receptor‐2 (VEGFR2) is a major regulator of endothelial cell (EC) functions, including angiogenesis. Although most studies of…”
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Evidence against dopamine D1/D2 receptor heteromers by Frederick, A L, Yano, H, Trifilieff, P, Vishwasrao, H D, Biezonski, D, Mészáros, J, Urizar, E, Sibley, D R, Kellendonk, C, Sonntag, K C, Graham, D L, Colbran, R J, Stanwood, G D, Javitch, J A

“…Hetero-oligomers of G-protein-coupled receptors have become the subject of intense investigation, because their purported potential to manifest signaling and…”
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TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation by Thoppil, Roslin J., Adapala, Ravi K., Cappelli, Holly C., Kondeti, Vinay, Dudley, Andrew C., Gary Meszaros, J., Paruchuri, Sailaja, Thodeti, Charles K.

“…Endothelial cell proliferation is a critical event during angiogenesis, regulated by both soluble factors and mechanical forces. Although the proliferation of…”
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A systematic review of sensorimotor function during adolescence: a developmental stage of increased motor awkwardness? by Quatman-Yates, Catherine C, Quatman, Carmen E, Meszaros, Andrew J, Paterno, Mark V, Hewett, Timothy E

“…Although adolescent motor awkwardness and increased injury susceptibility have often been speculated and researched, studies regarding adolescent regressions…”
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TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals by Adapala, Ravi K, Thoppil, Roslin J, Luther, Daniel J, Paruchuri, Sailaja, Meszaros, J. Gary, Chilian, William M, Thodeti, Charles K

“…Abstract The phenotypic switch underlying the differentiation of cardiac fibroblasts into hypersecretory myofibroblasts is critical for cardiac remodeling…”
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Absence of Type VI Collagen Paradoxically Improves Cardiac Function, Structure, and Remodeling After Myocardial Infarction by Luther, Daniel J, Thodeti, Charles K, Shamhart, Patricia E, Adapala, Ravi K, Hodnichak, Cheryl, Weihrauch, Dorothee, Bonaldo, Paolo, Chilian, William M, Meszaros, J Gary

“…RATIONALE:We previously reported that type VI collagen deposition increases in the infarcted myocardium in vivo. To date, a specific role for this nonfibrillar…”
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PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells by Adapala, Ravi K, Talasila, Phani K, Bratz, Ian N, Zhang, David X, Suzuki, Makoto, Meszaros, J Gary, Thodeti, Charles K

“…Transient receptor potential vanilloid channel 4 (TRPV4) is a polymodally activated nonselective cationic channel implicated in the regulation of vasodilation…”
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Development and validation of technologies suitable for the decontamination and re-use of contaminated N95 filtering facepiece respirators in response to the COVID-19 pandemic by Alt, J., Eveland, R., Fiorello, A., Haas, B., Meszaros, J., McEvoy, B., Ridenour, C., Shaffer, D., Yirava, W., Ward, L.

“…Coronavirus disease 2019 (COVID-19) has brought significant challenges to society globally, particularly in the area of healthcare provision. A pressing need…”
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Non-fibrillar collagens: Key mediators of post-infarction cardiac remodeling? by Shamhart, Patricia E, Meszaros, J. Gary

“…Abstract Cardiac remodeling is accelerated during pathological conditions and several anabolic and catabolic regulators work in concert to repair the…”
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Prevalence and characterization of Salmonella infantis isolates originating from different points of the broiler chicken–human food chain in Hungary by Nógrády, N., Kardos, G., Bistyák, A., Turcsányi, I., Mészáros, J., Galántai, Zs, Juhász, Á., Samu, P., Kaszanyitzky, J.É., Pászti, J., Kiss, I.

“…During the 10-month study period Salmonella contamination of broiler houses and the flocks reared in three farms (A, B and C), the slaughter houses where the…”
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Inhibition of Cardiac Myofibroblast Formation and Collagen Synthesis by Activation and Overexpression of Adenylyl Cyclase by Swaney, James S., Roth, David M., Olson, Erik R., Naugle, Jennifer E., Meszaros, J. Gary, Insel, Paul A., Seegmiller, J. Edwin

“…Transformation of fibroblasts to myofibroblasts, characterized by expression of α-smooth muscle actin (α-SMA) and production of extracellular matrix (ECM)…”
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Disruption of TRPV1-mediated coupling of coronary blood flow to cardiac metabolism in diabetic mice: role of nitric oxide and BK channels by Guarini, Giacinta, Ohanyan, Vahagn A, Kmetz, John G, DelloStritto, Daniel J, Thoppil, Roslin J, Thodeti, Charles K, Meszaros, J Gary, Damron, Derek S, Bratz, Ian N

“…We have previously shown transient receptor potential vanilloid subtype 1 (TRPV1) channel-dependent coronary function is compromised in pigs with metabolic…”
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From farm to fork follow-up of thermotolerant campylobacters throughout the broiler production chain and in human cases in a Hungarian county during a ten-months period by Damjanova, I., Jakab, M., Farkas, T., Mészáros, J., Galántai, Zs, Turcsányi, I., Bistyák, A., Juhász, Á., Pászti, J., Kiss, I., Kardos, G.

“…A study tracking thermotolerant campylobacters from the setting of the broilers throughout the whole rearing period, slaughter and sale of chicken products in…”
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Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signaling by Stockand, James D, Meszaros, J Gary

“…Aldosterone plays a pathological role in cardiac fibrosis by directly affecting cardiac fibroblasts. Understanding of the cellular mechanisms of aldosterone…”
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Overexpressing superoxide dismutase 2 induces a supernormal cardiac function by enhancing redox-dependent mitochondrial function and metabolic dilation by Kang, Patrick T, Chen, Chwen-Lih, Ohanyan, Vahagn, Luther, Daniel J, Meszaros, J. Gary, Chilian, William M, Chen, Yeong-Renn

“…Abstract During heightened cardiac work, O2 consumption by the heart benefits energy production via mitochondria. However, some electrons leak from the…”
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Pomegranate phytoconstituents blunt the inflammatory cascade in a chemically induced rodent model of hepatocellular carcinogenesis by Bishayee, Anupam, Thoppil, Roslin J, Darvesh, Altaf S, Ohanyan, Vahagn, Meszaros, J. Gary, Bhatia, Deepak

“…Liver cancer, predominantly hepatocellular carcinoma (HCC), represents a complex and fatal malignancy driven primarily by oxidative stress and inflammation…”
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Angiotensin II–Induced Extracellular Signal–Regulated Kinase 1/2 Activation Is Mediated by Protein Kinase Cδ and Intracellular Calcium in Adult Rat Cardiac Fibroblasts by Olson, Erik R, Shamhart, Patricia E, Naugle, Jennifer E, Meszaros, J Gary

“…Angiotensin II (Ang II)–induced proliferation of cardiac fibroblasts is a major contributing factor to the pathogenesis of cardiac fibrosis. Ang II activates…”
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Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol by Olson, Erik R, Naugle, Jennifer E, Zhang, Xiaojin, Bomser, Joshua A, Meszaros, J Gary

“…Cardiac fibroblasts (CFs) regulate myocardial remodeling by proliferating, differentiating, and secreting extracellular matrix proteins. Prolonged activation…”
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A TRP to cardiac fibroblast differentiation by Thodeti, Charles K., Paruchuri, Sailaja, Meszaros, J. Gary

“…The differentiation of cardiac fibroblasts to myofibroblasts is one of the key events during cardiac remodeling, however, the molecular mechanism underlying…”
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