Search Results - "Mesyngier, Maia"
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In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography
Published in Nature methods (01-10-2020)“…The immune system’s ability to recognize peptides on major histocompatibility molecules contributes to the eradication of cancers and pathogens. Tracking these…”
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623 Immuno-STATs: Leveraging protein engineering to expand and track antigen-specific T cells in vivo
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundImmunotherapies are highly promising and effective strategies for the treatment of cancer; however, continuing challenges persist, including 1)…”
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Targeted delivery of antigens to CD11b+ cells via nanobodies induces strong antigen-specific T cell and anti-tumor responses
Published in The Journal of immunology (1950) (01-05-2018)“…The variable regions of camelid heavy chain-only antibodies (nanobodies or VHHs) are the smallest antibody fragments that retain full antigen binding. Owing to…”
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Nanobody-Antigen Conjugates Elicit HPV-Specific Antitumor Immune Responses
Published in Cancer immunology research (01-07-2018)“…High-risk human papillomavirus-associated cancers express viral oncoproteins (e.g., E6 and E7) that induce and maintain the malignant phenotype. The viral…”
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