Search Results - "Mesulam, M."

Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer's disease by Mesulam, M.-Marsel

“…ABSTRACT The nucleus basalis is located at the confluence of the limbic and reticular activating systems. It receives dopaminergic input from the ventral…”
Get full text

Quantitative classification of primary progressive aphasia at early and mild impairment stages by MESULAM, M.-Marsel, WIENEKE, Christina, THOMPSON, Cynthia, ROGALSKI, Emily, WEINTRAUB, Sandra

“…The characteristics of early and mild disease in primary progressive aphasia are poorly understood. This report is based on 25 patients with aphasia quotients…”
Get full text

Temporopolar regions of the human brain by Mesulam, M Marsel

“…Following prolonged neglect during the formative decades of behavioural neurology, the temporopolar region has become a site of vibrant research on the…”
Get full text

The cholinergic system in the pathophysiology and treatment of Alzheimer's disease by Hampel, Harald, Mesulam, M.-Marsel, Cuello, A Claudio, Farlow, Martin R, Giacobini, Ezio, Grossberg, George T, Khachaturian, Ara S, Vergallo, Andrea, Cavedo, Enrica, Snyder, Peter J, Khachaturian, Zaven S

“…Hampel et al. review the role of the cholinergic system in cognition and how cholinergic deficits in Alzheimer's disease interact with other aspects of disease…”
Get full text

Primary progressive aphasia and the evolving neurology of the language network by Mesulam, M.-Marsel, Rogalski, Emily J., Wieneke, Christina, Hurley, Robert S., Geula, Changiz, Bigio, Eileen H., Thompson, Cynthia K., Weintraub, Sandra

“…Key Points Primary progressive aphasia (PPA) is a clinical syndrome caused by selective neurodegeneration of the language-dominant cerebral hemisphere, thus…”
Get full text

Progression of language decline and cortical atrophy in subtypes of primary progressive aphasia by ROGALSKI, E, COBIA, D, HARRISON, T. M, WIENEKE, C, WEINTRAUB, S, MESULAM, M.-M

“…To examine the longitudinal course of primary progressive aphasia (PPA) over a 2-year period and to offer quantitative ranges of expected change that could be…”
Get full text

The Wernicke conundrum and the anatomy of language comprehension in primary progressive aphasia by Mesulam, M-Marsel, Thompson, Cynthia K, Weintraub, Sandra, Rogalski, Emily J

“…Wernicke's aphasia is characterized by severe word and sentence comprehension impairments. The location of the underlying lesion site, known as Wernicke's…”
Get full text

Words and Objects at the Tip of the Left Temporal Lobe in Primary Progressive Aphasia by Mesulam, M.-Marsel, Wieneke, Christina, Hurley, Robert, Rademaker, Alfred, Thompson, Cynthia K, Weintraub, Sandra, Rogalski, Emily J

“…Eleven of 69 prospectively enrolled primary progressive aphasics were selected for this study because of peak atrophy sites located predominantly or…”
Get full text

Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia by MESULAM, M.-Marsel, WEINTRAUB, Sandra, ROGALSKI, Emily J, WIENEKE, Christina, GEULA, Changiz, BIGIO, Eileen H

“…Fifty-eight autopsies of patients with primary progressive aphasia are reported. Twenty-three of these were previously described (Mesulam et al., 2008) but had…”
Get full text

Medical characterization of cognitive SuperAgers: Investigating the medication profile of SuperAgers by Engelmeyer, Janessa R, Kerr, Alice, Makowski-Woidan, Beth A, Gill, Nathan P, Mesulam, M-Marsel, Weintraub, Sandra, Zhang, Hui, Lindquist, Lee, Rogalski, Emily J

Get full text

Is it time to revisit the classification guidelines for primary progressive aphasia? by Mesulam, M.-Marsel, Weintraub, Sandra

Get full text

Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia by GEFEN, Tamar, GASHO, Katherine, RADEMAKER, Alfred, LALEHZARI, Mona, WEINTRAUB, Sandra, ROGALSKI, Emily, WIENEKE, Christina, BIGIO, Eileen, GEULA, Changiz, MESULAM, M.-Marsel

“…Primary progressive aphasia is a neurodegenerative syndrome characterized by gradual dissolution of language but relative sparing of other cognitive domains,…”
Get full text

Network-targeted stimulation engages neurobehavioral hallmarks of age-related memory decline by Nilakantan, Aneesha S, Mesulam, M.-Marsel, Weintraub, Sandra, Karp, Erica L, VanHaerents, Stephen, Voss, Joel L

“…OBJECTIVETo test whether targeting hippocampal-cortical brain networks with high-frequency transcranial magnetic stimulation in older adults influences…”
Get full text

Memory improvement via slow-oscillatory stimulation during sleep in older adults by Westerberg, Carmen E, Florczak, Susan M, Weintraub, Sandra, Mesulam, M. -Marsel, Marshall, Lisa, Zee, Phyllis C, Paller, Ken A

“…Abstract We examined the intriguing but controversial idea that disrupted sleep-dependent consolidation contributes to age-related memory decline. Slow-wave…”
Get full text

Neural repetition suppression reflects fulfilled perceptual expectations by Egner, Tobias, Summerfield, Christopher, Trittschuh, Emily H, Monti, Jim M, Mesulam, M-Marsel

“…Stimulus-evoked neural activity is attenuated on stimulus repetition (repetition suppression), a phenomenon that is attributed to largely automatic processes…”
Get full text

Morphometric and histologic substrates of cingulate integrity in elders with exceptional memory capacity by Gefen, Tamar, Peterson, Melanie, Papastefan, Steven T, Martersteck, Adam, Whitney, Kristen, Rademaker, Alfred, Bigio, Eileen H, Weintraub, Sandra, Rogalski, Emily, Mesulam, M-Marsel, Geula, Changiz

“…This human study is based on an established cohort of "SuperAgers," 80+-year-old individuals with episodic memory function at a level equal to, or better than,…”
Get full text

Primary progressive aphasia by Mesulam, M.-Marsel

“…Primary progressive aphasia (PPA) is a focal dementia characterized by an isolated and gradual dissolution of language function. The disease starts with…”
Get full text

Asymmetry of cortical decline in subtypes of primary progressive aphasia by Rogalski, Emily, Cobia, Derin, Martersteck, Adam, Rademaker, Alfred, Wieneke, Christina, Weintraub, Sandra, Mesulam, M.-Marsel

“…OBJECTIVE:The aim of this study was to provide quantitative measures of changes in cortical atrophy over a 2-year period associated with 3 subtypes of primary…”
Get full text

Primary progressive aphasia and the language network: The 2013 H. Houston Merritt Lecture by Mesulam, M.-Marsel

“…OBJECTIVE:Review of clinical and biological features of primary progressive aphasia (PPA). RESULTS AND CONCLUSIONS:The PPA syndrome arises when…”
Get full text

Variations in Acetylcholinesterase Activity within Human Cortical Pyramidal Neurons Across Age and Cognitive Trajectories by Janeczek, Monica, Gefen, Tamar, Samimi, Mehrnoosh, Kim, Garam, Weintraub, Sandra, Bigio, Eileen, Rogalski, Emily, Mesulam, M -Marsel, Geula, Changiz

“…Abstract We described an extensive network of cortical pyramidal neurons in the human brain with abundant acetylcholinesterase (AChE) activity. Emergence of…”
Get full text