Search Results - "Messias‐Reason, Iara"

Chagas Disease: From Discovery to a Worldwide Health Problem by Lidani, Kárita Cláudia Freitas, Andrade, Fabiana Antunes, Bavia, Lorena, Damasceno, Flávia Silva, Beltrame, Marcia Holsbach, Messias-Reason, Iara J, Sandri, Thaisa Lucas

“…Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in his honor, just over a century ago. He described the clinical aspects of…”
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Autoimmunity in Chronic Chagas Disease: A Road of Multiple Pathways to Cardiomyopathy? by De Bona, Elidiana, Lidani, Kárita Cláudia Freitas, Bavia, Lorena, Omidian, Zahra, Gremski, Luiza Helena, Sandri, Thaisa Lucas, de Messias Reason, Iara J

“…Chagas disease (CD), a neglected tropical disease caused by the protozoan , affects around six million individuals in Latin America. Currently, CD occurs…”
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Association of a new FCN3 haplotype with high ficolin-3 levels in leprosy by Andrade, Fabiana Antunes, Beltrame, Marcia Holsbach, Bini, Valéria Bumiller, Gonçalves, Letícia Boslooper, Boldt, Angelica Beate Winter, de Messias-Reason, Iara Jose

“…Leprosy is a chronic inflammatory disease caused by Mycobacterium leprae that mainly affects the skin and peripheral nervous system, leading to a high…”
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Association of L-ficolin levels and FCN2 genotypes with chronic Chagas disease by Luz, Paola R, Boldt, Angelica B W, Grisbach, Caroline, Kun, Jürgen F J, Velavan, Thirumalaisamy P, Messias-Reason, Iara J T

“…L-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the…”
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Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy by Kretzschmar, Gabriela Canalli, Oliveira, Luana Caroline, Nisihara, Renato Mitsunori, Velavan, Thirumalaisamy P, Stinghen, Sérvio Túlio, Stahlke, Ewalda R S, Petzl-Erler, Maria Luiza, Messias-Reason, Iara José T de, Boldt, Angelica Beate Winter

“…Pathophysiological mechanisms are still incompletely understood for leprosy, an urgent public health issue in Brazil. Complement receptor 1 (CR1) binds…”
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The lectin pathway of complement and rheumatic heart disease by Beltrame, Marcia Holsbach, Catarino, Sandra Jeremias, Goeldner, Isabela, Boldt, Angelica Beate Winter, de Messias-Reason, Iara José

“…The innate immune system is the first line of host defense against infection and is comprised of humoral and cellular mechanisms that recognize potential…”
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Ficolin‐3 in chronic Chagas disease: Low serum levels associated with the risk of cardiac insufficiency by Lidani, Kárita Cláudia Freitas, Andrade, Fabiana Antunes, Beltrame, Marcia Holsbach, Chakravarti, Indira, Tizzot, Maria Regina, Cavalcanti, Edneia Oliveira, Sandri, Thaisa Lucas, Luz, Paola Rosa, Messias‐Reason, Iara J.

“…Aims To investigate whether FCN3 polymorphisms and circulating ficolin‐3 levels were associated with clinical forms of chronic Chagas disease (CD) and to…”
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Serum pentraxin 3 levels are negatively associated with carotid intima media thickness in non-obese rheumatoid arthritis patients by Kahlow, Barbara Stadler, Petisco, Roberta, Skare, Thelma Larocca, Goeldner, Isabela, Nisihara, Renato M, Messias-Reason, Iara J.T

“…Abstract Background Pentraxin-3 (PTX3) is a long pentraxin that is supposed to participate in the inflammatory process and in atherosclerosis. Aim To study…”
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Mannose binding lectin and susceptibility to rheumatoid arthritis in Brazilian patients and their relatives by Goeldner, Isabela, Skare, Thelma L, Utiyama, Shirley R, Nisihara, Renato M, Tong, Hoang van, Messias-Reason, Iara J T, Velavan, Thirumalaisamy P

“…Rheumatoid arthritis (RA) is a commonly occurring systemic inflammatory auto immune disease and is believed to be associated with genetic factors. The innate…”
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Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels by Weinschutz Mendes, Hellen, Boldt, Angelica Beate Winter, von Rosen Seeling Stahlke, Ewalda, Jensenius, Jens Christian, Thiel, Steffen, Messias-Reason, Iara J Taborda

“…Deposition of complement factors on Mycobacterium leprae may enhance phagocytosis. Such deposition may occur through the lectin pathway of complement. Three…”
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MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease by Boldt, Angelica B.W, Luz, Paola R, Messias-Reason, Iara J.T

“…Abstract Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-associated serine protease 2 (MASP2). We haplotyped six MASP2…”
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Impact of VSIG4 gene polymorphisms on susceptibility and functional status of rheumatoid arthritis by Andrade, Fabiana, Eibofner, Isabela, Pieczarka, Cristhine, van Tong, Hoang, Sena, Leia, Skare, Thelma, Utiyama, Shirley, Messias‐Reason, Iara, Velavan, Thirumalaisamy

“…The complement receptor of the immunoglobulin superfamily (CRIg, encoded by the VSIG4 gene) is a macrophage receptor involved in the clearance of immune…”
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IL-4 haplotype -590T, -34T and intron-3 VNTR R2 is associated with reduced malaria risk among ancestral indian tribal populations by Jha, Aditya Nath, Singh, Vipin Kumar, Kumari, Namrata, Singh, Ashish, Antony, Justin, van Tong, Hoang, Singh, Sakshi, Pati, Sudhanshu S, Patra, Pradeep K, Singh, Rajender, Toan, Nguyen L, Song, Le H, Assaf, Amal, Messias-Reason, Iara J T, Velavan, Thirumalaisamy P, Singh, Lalji, Thangaraj, Kumarasamy

“…Interleukin 4 (IL-4) is an anti-inflammatory cytokine, which regulates balance between T(H)1 and T(H)2 immune response, immunoglobulin class switching and…”
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Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease by Sandri, Thaisa Lucas, Andrade, Fabiana Antunes, Lidani, Kárita Cláudia Freitas, Einig, Elias, Boldt, Angelica Beate Winter, Mordmüller, Benjamin, Esen, Meral, Messias-Reason, Iara J

“…Chagas Disease (CD) is an anthropozoonosis caused by Trypanosoma cruzi. With complex pathophysiology and variable clinical presentation, CD outcome can be…”
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Nutrition and Cancercapsaicin Treatment Reduces Tumor Growth, Tumor Cell Proliferation Ex Vivo and Partially Reverses Cancer Cachexia in Walker 256 Tumor-Bearing Rats by Ricardo de Brito Bello, Sérgio, Naliwaiko, Katya, Vicentini, Mariana Scudeller, Rossetti, Francini Xavier, Claudio Fernandes, Luiz, Messias-Reason, Iara José de

“…Capsaicin (trans-8-methyl-n-vanillyl-6-nonenamide) is the main pungent component found in hot peppers. Aim: In this study, we investigated the effect of…”
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Leprosy association with low MASP-2 levels generated by MASP2 haplotypes and polymorphisms flanking MAp19 exon 5 by Boldt, Angelica Beate Winter, Goeldner, Isabela, Stahlke, Ewalda R S, Thiel, Steffen, Jensenius, Jens Christian, de Messias-Reason, Iara José Taborda

“…The gene MASP2 (mannan-binding lectin (MBL)-associated serine protease 2) encodes two proteins, MASP-2 and MAp19 (MBL-associated protein of 19 kDa), bound in…”
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The Second Highest Prevalence of Celiac Disease Worldwide: Genetic and Metabolic Insights in Southern Brazilian Mennonites by Oliveira, Luana Caroline, Dornelles, Amanda Coelho, Nisihara, Renato Mitsunori, Bruginski, Estevan Rafael Dutra, Santos, Priscila Ianzen Dos, Cipolla, Gabriel Adelman, Boschmann, Stefanie Epp, Messias-Reason, Iara José de, Campos, Francinete Ramos, Petzl-Erler, Maria Luiza, Boldt, Angelica Beate Winter

“…Celiac disease (CD), despite its high morbidity, is an often-underdiagnosed autoimmune enteropathy. Using a modified version of the Brazilian questionnaire of…”
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Genetically Determined MBL Deficiency Is Associated with Protection against Chronic Cardiomyopathy in Chagas Disease by Luz, Paola Rosa, Miyazaki, Márcia I, Chiminacio Neto, Nelson, Padeski, Marcela C, Barros, Ana Cláudia M, Boldt, Angelica B W, Messias-Reason, Iara J

“…Chagas disease (CD) is caused by Trypanosoma cruzi, whose sugar moieties are recognized by mannan binding lectin (MBL), a soluble pattern-recognition molecule…”
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Association of MASP-2 levels and MASP2 gene polymorphisms with rheumatoid arthritis in patients and their relatives by Goeldner, Isabela, Skare, Thelma, Boldt, Angelica B W, Nass, Flavia R, Messias-Reason, Iara J, Utiyama, Shirley R

“…Mannan-binding lectin-associated serine protease 2 (MASP-2) is a key protein of the lectin pathway of complement. MASP-2 levels have been associated with…”
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Ficolin-1 and Ficolin-3 Plasma Levels Are Altered in HIV and HIV/HCV Coinfected Patients From Southern Brazil by Tizzot, Maria Regina, Lidani, Kárita Cláudia Freitas, Andrade, Fabiana Antunes, Mendes, Hellen Weinschutz, Beltrame, Marcia Holsbach, Reiche, Edna, Thiel, Steffen, Jensenius, Jens C, de Messias-Reason, Iara J

“…The complement system is a key component of the innate immune system, participating in the surveillance against infectious agents. Once activated by one of the…”
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